DR. NIYIKIZA
`Dee paar.
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`NEPTUNE DX - 212
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`
`Dee paar.
`
`
`NEPTUNE DX - 212
`
`
`
`Dr. Niyikiza
`Dr. Niyikiza Testimony
`
`Source: Ex. 2116 at 4-712:8-11; Paper 48 at 30.
`
`NEPTUNE DX - 213
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`
`
`Dr. Niyikiza
`Dr. Niyikiza Testimony
`
`Source: Ex. 2116 at 4-744:10-4-745-15; Paper 48 at 30-31.
`
`NEPTUNE DX - 214
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`
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`DR. BLEYER
`DR. BLEYER
`
`
`NEPTUNE DX - 215
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶69; Paper 48 at 8-9.
`
`NEPTUNE DX - 216
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶69; Paper 48 at 8-9.
`
`NEPTUNE DX - 217
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶69; Paper 48 at 8-9.
`
`NEPTUNE DX - 218
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶69; Paper 48 at 8-9.
`
`NEPTUNE DX - 219
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶69; Paper 48 at 8-9.
`
`NEPTUNE DX - 220
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶70; Paper 48 at 8-10.
`
`NEPTUNE DX - 221
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶70; Paper 48 at 8-10.
`
`NEPTUNE DX - 222
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶70; Paper 48 at 8-10.
`
`NEPTUNE DX - 223
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶70; Paper 48 at 8-10.
`
`NEPTUNE DX - 224
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶70; Paper 48 at 8-10.
`
`NEPTUNE DX - 225
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶71; Paper 48 at 8-9.
`
`NEPTUNE DX - 226
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶71; Paper 48 at 8-9.
`
`NEPTUNE DX - 227
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶71; Paper 48 at 8-9.
`
`NEPTUNE DX - 228
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶16; Paper 48 at 8-9.
`
`NEPTUNE DX - 229
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶19(a-c); Paper 48 at 8-9.
`
`NEPTUNE DX - 230
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶20(a-b); Paper 48 at 8-9.
`
`NEPTUNE DX - 231
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶20(c-d); Paper 48 at 8-9.
`
`NEPTUNE DX - 232
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶22(a-b); Paper 48 at 8-9.
`
`NEPTUNE DX - 233
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶23(b-f); Paper 48 at 8-9.
`
`NEPTUNE DX - 234
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶24(a-d); Paper 48 at 8-9.
`
`NEPTUNE DX - 235
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶24(e-h); Paper 48 at 8-9.
`
`NEPTUNE DX - 236
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶24(i); Paper 48 at 8-9.
`
`NEPTUNE DX - 237
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶37(a-b)-38; Paper 48 at 8-9.
`
`NEPTUNE DX - 238
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶28(a-c); Paper 48 at 8-9.
`
`NEPTUNE DX - 239
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶28(d-f); Paper 48 at 8-9.
`
`NEPTUNE DX - 240
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶28(g); Paper 48 at 8-9.
`
`NEPTUNE DX - 241
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶50; Paper 48 at 8-9.
`
`NEPTUNE DX - 242
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶45; Paper 48 at 8-9.
`
`NEPTUNE DX - 243
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶27(a); Paper 48 at 16.
`
`NEPTUNE DX - 244
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶29; Paper 48 at 17.
`
`NEPTUNE DX - 245
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶29(a-e); Paper 48 at 17.
`
`NEPTUNE DX - 246
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶29(f-j); Paper 48 at 17.
`
`NEPTUNE DX - 247
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶30; Paper 48 at 18.
`
`NEPTUNE DX - 248
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶31; Paper 48 at 18.
`
`NEPTUNE DX - 249
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶40(a-b); Paper 48 at 18, 20.
`
`NEPTUNE DX - 250
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶40(c-d); Paper 48 at 18, 20, 22.
`
`NEPTUNE DX - 251
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶40(e-f); Paper 48 at 18, 20, 22.
`
`NEPTUNE DX - 252
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶47(a-c); Paper 48 at 20.
`
`NEPTUNE DX - 253
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶47(d-e); Paper 48 at 20.
`
`NEPTUNE DX - 254
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶47(f-g); Paper 48 at 20.
`
`NEPTUNE DX - 255
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶47(h); Paper 48 at 20.
`
`NEPTUNE DX - 256
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶51(a-b); Paper 48 at 20-27, 29.
`
`NEPTUNE DX - 257
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶51(c-d); Paper 48 at 20-27, 29.
`
`NEPTUNE DX - 258
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶62(a-c); Paper 48 at 20.
`
`NEPTUNE DX - 259
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶64(a-b); Paper 48 at 20.
`
`NEPTUNE DX - 260
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶53; Paper 48 at 21.
`
`NEPTUNE DX - 261
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶14(a-b); Paper 48 at 22.
`
`NEPTUNE DX - 262
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶14(c); Paper 48 at 22.
`
`NEPTUNE DX - 263
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶52; Paper 48 at 23.
`
`NEPTUNE DX - 264
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶63(a-c); Paper 48 at 25.
`
`NEPTUNE DX - 265
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶65; Paper 48 at 25.
`
`NEPTUNE DX - 266
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶66(a-b), 67; Paper 48 at 25.
`
`NEPTUNE DX - 267
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶54(a-c); Paper 48 at 27.
`
`NEPTUNE DX - 268
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶57; Paper 48 at 28.
`
`NEPTUNE DX - 269
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶41(a-b); Paper 48 at 29.
`
`NEPTUNE DX - 270
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶41(c-d); Paper 48 at 29.
`
`NEPTUNE DX - 271
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶¶41(e-f); Paper 48 at 29.
`
`NEPTUNE DX - 272
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1077 at ¶42; Paper 48 at 29.
`
`NEPTUNE DX - 273
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`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 1025 at ¶¶147, 152, 158-159; Paper 48 at 30.
`
`NEPTUNE DX - 274
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`
`
`DR. MASON
`DR. MASON
`
`
`NEPTUNE DX - 275
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶22-26; Paper 48 at 12.
`
`NEPTUNE DX - 276
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶27-30; Paper 48 at 12.
`
`NEPTUNE DX - 277
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`
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`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶31-32; Paper 48 at 12.
`
`NEPTUNE DX - 278
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶33-35; Paper 48 at 12.
`
`NEPTUNE DX - 279
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶46; Paper 48 at 12-13.
`
`NEPTUNE DX - 280
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶40-42; Paper 48 at 13.
`
`NEPTUNE DX - 281
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶43-45; Paper 48 at 13.
`
`NEPTUNE DX - 282
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶84-86; Paper 48 at 20, 22.
`
`NEPTUNE DX - 283
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶87, 94; Paper 48 at 20, 22.
`
`NEPTUNE DX - 284
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶80-82; Paper 48 at 22.
`
`NEPTUNE DX - 285
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶91; Paper 48 at 22.
`
`NEPTUNE DX - 286
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶58-61; Paper 48 at 26.
`
`NEPTUNE DX - 287
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶62-66; Paper 48 at 26.
`
`NEPTUNE DX - 288
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶67; Paper 48 at 26.
`
`NEPTUNE DX - 289
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶76-77; Paper 48 at 26.
`
`NEPTUNE DX - 290
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶73; Paper 48 at 26.
`
`NEPTUNE DX - 291
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶52, 54; Paper 48 at 27.
`
`NEPTUNE DX - 292
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶75; Paper 48 at 27.
`
`NEPTUNE DX - 293
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶53, 55-56; Paper 48 at 27.
`
`NEPTUNE DX - 294
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶70; Paper 48 at 30.
`
`NEPTUNE DX - 295
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶¶68, 71; Paper 48 at 31.
`
`NEPTUNE DX - 296
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`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 1078 at ¶90; Paper 48 at 31.
`
`NEPTUNE DX - 297
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`
`
`DR. FEIGAL
`Dee cre
`
`
`NEPTUNE DX - 298
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`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 1080 at ¶¶ 27-28; Paper 48 at 16.
`
`NEPTUNE DX - 299
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 1080 at ¶¶39(a-d); Paper 48 at 33.
`
`NEPTUNE DX - 300
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 1080 at ¶¶40-41; Paper 48 at 33.
`
`NEPTUNE DX - 301
`
`
`
`PETITION
`PETITION
`
`
`NEPTUNE DX - 302
`
`
`
`Petition
`
`-00240 Petition
`
`Source: Paper 01 at 19 (-00240); Paper 48 at 18-19.
`
`NEPTUNE DX - 303
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`
`
`PATENT OWNER’S
`A eaae
`RESPONSE
`RESPONSE
`
`
`NEPTUNE DX - 304
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`
`
`Patent Owner’s Response
`Patent Owner’s Response
`
`Source: Paper 33 at 5; Paper 48 at 16.
`
`NEPTUNE DX - 305
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`
`
`Patent Owner’s Response
`Patent Owner’s Response
`
`Source: Paper 33 at 10; Paper 48 at 12.
`
`NEPTUNE DX - 306
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`
`
`Patent Owner’s Response
`Patent Owner’s Response
`
`Source: Paper 33 at 26; Paper 48 at 16.
`
`NEPTUNE DX - 307
`
`
`
`Patent Owner’s Response
`Patent Owner’s Response
`
`Source: Paper 33 at 10-11; Paper 48 at 18-19.
`
`NEPTUNE DX - 308
`
`
`
`Patent Owner’s Response
`Patent Owner’s Response
`
`Source: Paper 33 at 2; Paper 48 at 23.
`
`NEPTUNE DX - 309
`
`
`
`Patent Owner’s Response
`Patent Owner’s Response
`
`Source: Paper 33 at 7; Paper 48 at 27.
`
`NEPTUNE DX - 310
`
`
`
`Patent Owner’s Response
`Patent Owner’s Response
`
`Source: Paper 33 at 42; Paper 48 at 21.
`
`NEPTUNE DX - 311
`
`
`
`FEDERAL CIRCUIT
`FEDERAL CIRCUIT
`DECISION
`DECISION
`
`
`NEPTUNE DX - 312
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`IPR Evidence Not Before Federal Circuit:
`
`vs.
`
`Source: Paper 63 at 15; Paper 33 at 55.
`
`NEPTUNE DX - 313
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`IPR Evidence Not Before Federal Circuit:
`
`vs.
`
`Source: Paper 63 at 15; Ex. 2121 at 1-2; Ex. 1075 at 9:4-5, 23-24.
`
`NEPTUNE DX - 314
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`IPR Evidence Not Before Federal Circuit:
`
`vs.
`
`Source: Paper 63 at 15; Ex. 2121 at 1-2; Ex. 1057 at 1, 4, 18.
`
`NEPTUNE DX - 315
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`IPR Evidence Not Before Federal Circuit:
`
`Source: Paper 63 at 15; Paper 13 at 19; Paper 14 at 19 (IPR2016-00240).
`
`NEPTUNE DX - 316
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit
`Ruling:
`
`IPR Evidence Not
`Before Federal
`Circuit:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 26; Ex. 1076 at 116:12-20; Paper 48 at 24.
`
`NEPTUNE DX - 317
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit Ruling:
`
`IPR Evidence Not Before Fed. Cir.: EP 005:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 26-27; Ex. 1010 at 4, 9; Paper 48 at 21-22.
`
`NEPTUNE DX - 318
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit Ruling:
`
`IPR Evidence Not Before Fed. Cir.: EP 005:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 27; Ex. 1010 at 4, 9; Paper 48 at 21-22.
`
`NEPTUNE DX - 319
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit Ruling:
`
`IPR Evidence Not Before Federal Circuit:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 27; Ex. 1063 at 1277S-78S; Paper 48 at 21-22.
`
`NEPTUNE DX - 320
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit Ruling:
`
`IPR Evidence Not Before Federal Circuit:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 27; Ex. 1063 at 1277S-78S; Ex. 1099 at 190 Paper 48 at 21-22.
`
`NEPTUNE DX - 321
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit
`Ruling:
`
`IPR Evidence Not
`Before Federal
`Circuit: EP 005
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 27; Ex. 1010 at 8; Paper 48 at 35.
`
`NEPTUNE DX - 322
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit Ruling:
`
`IPR Evidence Not Before
`Federal Circuit: EP 005:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 27; Ex. 1010 at 4, 8-9; Paper 48 at 21-22, 35.
`
`NEPTUNE DX - 323
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit Ruling:
`
`IPR Evidence Not Before Federal Circuit:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 27; Ex. 2135 at 333:6-16; 336:25-337:11; Paper 64 at 12.
`
`NEPTUNE DX - 324
`
`
`
`Federal Circuit Decision
`Lilly’s Sur-Reply Argument:
`
`Federal Circuit Ruling:
`
`IPR Evidence Not Before Federal Circuit:
`
`Source: Paper 63 at 15; Fed. Cir. Slip Op. at 27; Ex. 2135 at 331:11-15, 332:8-13; Paper 64 at 12.
`
`NEPTUNE DX - 325
`
`
`
`OPPOSITION TO
`OPPOSITION TO
`MOTIONS FOR
`MOTIONS FOR
`OBSERVATION
`OBSERVATION
`
`
`NEPTUNE DX - 326
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 42:22-43:4, 43:19-45:12; Paper 64 at 2.
`
`NEPTUNE DX - 327
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 51:4-11; Paper 64 at 3.
`
`NEPTUNE DX - 328
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 54:4-10, 59:19-24; Paper 64 at 5.
`
`NEPTUNE DX - 329
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 344:11-25, 345:23-346:22; Paper 64 at 4.
`
`NEPTUNE DX - 330
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 59:4-18; Paper 64 at 4.
`
`NEPTUNE DX - 331
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 65:5-23, 67:9-68:12; Paper 64 at 4.
`
`NEPTUNE DX - 332
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 68:18-69:9; Paper 64 at 6.
`
`NEPTUNE DX - 333
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 149:19-150:4; Paper 64 at 7.
`
`NEPTUNE DX - 334
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 216:22-217:23; Paper 64 at 7.
`
`NEPTUNE DX - 335
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 121:23-24; Paper 64 at 7.
`
`NEPTUNE DX - 336
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 338:13-18, 339:2-23; Paper 64 at 7-8.
`
`NEPTUNE DX - 337
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 147:13-148:15, 155:20-156:2, 157:7-17; Paper 64 at 8.
`
`NEPTUNE DX - 338
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 156:17-23; Paper 64 at 8.
`
`NEPTUNE DX - 339
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 152:23-154:25; Paper 64 at 10.
`
`NEPTUNE DX - 340
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 164:23-167:7; Paper 64 at 11.
`
`NEPTUNE DX - 341
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 238:4-239:25; Paper 64 at 12.
`
`NEPTUNE DX - 342
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 240:2-241:20; Paper 64 at 12.
`
`NEPTUNE DX - 343
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 241:21-242:6; Paper 64 at 12.
`
`NEPTUNE DX - 344
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 331:11-332:24; Paper 64 at 12.
`
`NEPTUNE DX - 345
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 333:3-334:25; Paper 64 at 12.
`
`NEPTUNE DX - 346
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 335:2-337:15; Paper 64 at 12.
`
`NEPTUNE DX - 347
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 300:25-301:6; Paper 64 at 13.
`
`NEPTUNE DX - 348
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 257:22-258:5; Paper 64 at 13.
`
`NEPTUNE DX - 349
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 259:12-14; Paper 64 at 13.
`
`NEPTUNE DX - 350
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 258:14-19, 329:5-23, 334:25-335:13; Paper 64 at 14.
`
`NEPTUNE DX - 351
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 272:10-18; Paper 64 at 14.
`
`NEPTUNE DX - 352
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 273:5-8; Paper 64 at 14.
`
`NEPTUNE DX - 353
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 278:7-12; Paper 64 at 15.
`
`NEPTUNE DX - 354
`
`
`
`Dr. Bleyer
`Dr. Bleyer’s Testimony
`
`Source: Ex. 2135 at 274:2-8; Paper 64 at 15.
`
`NEPTUNE DX - 355
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 146:7-20; Paper 66 at 2-3.
`
`NEPTUNE DX - 356
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 182:11-14; Paper 66 at 3.
`
`NEPTUNE DX - 357
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 126:22-129:11; Paper 66 at 3.
`
`NEPTUNE DX - 358
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 126:22-129:11; Paper 66 at 3.
`
`NEPTUNE DX - 359
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 129:12-130:17; Paper 66 at 3.
`
`NEPTUNE DX - 360
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 140:18-141:7; Paper 66 at 3.
`
`NEPTUNE DX - 361
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 122:7-15; Paper 66 at 3.
`
`NEPTUNE DX - 362
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 21:10-21; Paper 66 at 4.
`
`NEPTUNE DX - 363
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 32:12-14; Paper 66 at 4.
`
`NEPTUNE DX - 364
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 186:17-21; Paper 66 at 5.
`
`NEPTUNE DX - 365
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 47:24-48:11; Paper 66 at 6.
`
`NEPTUNE DX - 366
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 65:12-22; Paper 66 at 6.
`
`NEPTUNE DX - 367
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 165:20-166:7; Paper 66 at 9.
`
`NEPTUNE DX - 368
`
`
`
`Dr. Mason
`Dr. Mason’s Testimony
`
`Source: Ex. 2134 at 170:25-171:22; Paper 66 at 10.
`
`NEPTUNE DX - 369
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 16:13-20; Paper 69 at 2.
`
`NEPTUNE DX - 370
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 18:3-14; Paper 69 at 2-3.
`
`NEPTUNE DX - 371
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 21:23-22:20; Paper 69 at 3.
`
`NEPTUNE DX - 372
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 18:22-19:4; Paper 69 at 3.
`
`NEPTUNE DX - 373
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 19:6-20:13; Paper 69 at 3-4.
`
`NEPTUNE DX - 374
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 93:14-18; Paper 69 at 4.
`
`NEPTUNE DX - 375
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 94:10-95:4; Paper 69 at 4.
`
`NEPTUNE DX - 376
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 96:3-20; Paper 69 at 4.
`
`NEPTUNE DX - 377
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 26:7-27:21; Paper 69 at 6.
`
`NEPTUNE DX - 378
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 69:10-20; Paper 69 at 6.
`
`NEPTUNE DX - 379
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 9:13-23, 11:10-12:2; Paper 69 at 7-8.
`
`NEPTUNE DX - 380
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 26:7-27:21; Paper 69 at 8.
`
`NEPTUNE DX - 381
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 41:19-43:25; Paper 69 at 9.
`
`NEPTUNE DX - 382
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 44:1-46:12; Paper 69 at 9.
`
`NEPTUNE DX - 383
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 52:21-53:10; Paper 69 at 9.
`
`NEPTUNE DX - 384
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 57:16-58:21; Paper 69 at 8-9.
`
`NEPTUNE DX - 385
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 78:22-79:25; Paper 69 at 8-9.
`
`NEPTUNE DX - 386
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 80:1-81:25; Paper 69 at 8-9.
`
`NEPTUNE DX - 387
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 82:1-83:25; Paper 69 at 8-9.
`
`NEPTUNE DX - 388
`
`
`
`Dr. Feigal
`Dr. Feigal’s Testimony
`
`Source: Ex. 2133 at 84:1-85:9; Paper 69 at 8-9.
`
`NEPTUNE DX - 389
`
`
`
`LEGAL AUTHORITY
`LEGAL AUTHORITY
`
`
`NEPTUNE DX - 390
`
`
`
`Legal Authority
`Hoffman-LaRocheInc. v. Apotex, Inc.
`
`Source: Hoffman-LaRoche Inc. v. Apotex, Inc., 748 F.3d 1326, 1331 (Fed. Cir. 2014); Paper 48 at 3.
`
`NEPTUNE DX - 391
`
`
`
`Legal Authority
`Thomas & Betts Corp. v. Litton Sys., Inc.
`
`Source: Thomas & Betts Corp. v. Litton Sys., Inc., 720 F.2d 1572, 1580-81 (Fed. Cir.1983); Paper 48 at 6.
`
`NEPTUNE DX - 392
`
`
`
`Legal Authority
`Ex Parte Raychem
`
`Source: Ex Parte Raychem, 1992 Pat. App. LEXIS 21, *10-11 & n. 4 (Bd. Pat. App. & Interferences June 30, 1992); Paper 48 at 7.
`
`NEPTUNE DX - 393
`
`
`
`Legal Authority
`Ex Parte Raychem
`
`Source: Ex Parte Raychem, 1992 Pat. App. LEXIS 21, *19-21 (Bd. Pat. App. & Interferences June 30, 1992); Paper 48 at 7.
`
`NEPTUNE DX - 394
`
`
`
`Legal Authority
`Ex Parte McGaughey
`
`Source: Ex Parte McGaughey, 1988 Pat. App. LEXIS 2, 13-15 (Bd. Pat. App. & Interferences Mar. 4, 1988); Paper 48 at 7.
`
`NEPTUNE DX - 395
`
`
`
`Legal Authority
`Fed. R. Evid. 801(d)(2)
`
`Source: Fed. R. Evid. 801(d)(2); Paper 48 at 7.
`
`NEPTUNE DX - 396
`
`
`
`Legal Authority
`Medichem S.A. v. RolaboS.I.
`
`Source: Medichem S.A. v. Rolabo S.I., 437 F.3d 1157, 1165 (Fed. Cir. 2006); Paper 48 at 15.
`
`NEPTUNE DX - 397
`
`
`
`Legal Authority
`Randall Mfg. v. Rea
`
`Source: Randall Mfg. v. Rea, 733 F.3d 1355, 1362 (Fed. Cir. 2013); Paper 48 at 19.
`
`NEPTUNE DX - 398
`
`
`
`Legal Authority
`
`In re Fulton
`
`Source: In re Fulton, 391 F.3d 1195, 1202 (Fed. Cir. 2004); Paper 48 at 25.
`
`NEPTUNE DX - 399
`
`
`
`Legal Authority
`In re Applied Materials, Inc.
`
`Source: In re Applied Materials, Inc., 692 F.3d 1289, 1295 (Fed. Cir. 2012); Paper 1 at 39-40.
`
`NEPTUNE DX - 400
`
`
`
`Legal Authority
`In re Peterson
`
`Source: In re Peterson, 315 F.3d 1325, 1329–30 (Fed. Cir. 2003); Paper 1 at 43.
`
`NEPTUNE DX - 401
`
`
`
`Legal Authority
`Sciele Pharma, Inc. v. LupinLtd.
`
`Source: Sciele Pharma, Inc. v. Lupin Ltd., 684 F.3d 1253, 1259 (Fed. Cir. 2012); Paper 1 at 44.
`
`NEPTUNE DX - 402
`
`
`
`Legal Authority
`ViiV Healthcare UK Ltd. v. LupinLtd.
`
`Source: ViiV Healthcare UK Ltd. v. Lupin Ltd., 6 F. Supp. 3d 461, 497 (D. Del. 2013); Paper 48 at 32.
`
`NEPTUNE DX - 403
`
`
`
`Legal Authority
`Bayer Healthcare Pharms., Inc. v. Watson Pharms., Inc.
`
`Source: Bayer Healthcare Pharms., Inc. v. Watson Pharms., Inc., 713 F.3d 1369, 1377 (Fed. Cir. 2013); Paper 48 at 33.
`
`NEPTUNE DX - 404
`
`
`
`Legal Authority
`Pharmastem Therapeutics, Inc. v. Viacell, Inc.
`
`Source: Pharmastem Therapeutics, Inc. v. Viacell, Inc., 491 F.3d 1342; Paper 48 at 11, 32, 33.
`
`NEPTUNE DX - 405
`
`
`
`Legal Authority
`In re CopaxoneConsol. Cases
`
`Source: In re Copaxone Consol. Cases, 2017 U.S. Dist. LEXIS 12168 at *58-59 (D. Del. Jan. 30, 2017); Paper 57 at 4-5.
`
`NEPTUNE DX - 406
`
`
`
`Legal Authority
`In re CopaxoneConsol. Cases
`
`Source: In re Copaxone Consol. Cases, 2017 U.S. Dist. LEXIS 12168 at *78 (D. Del. Jan. 30, 2017); Paper 57 at 4-5.
`
`NEPTUNE DX - 407
`
`
`
`Legal Authority
`In re CopaxoneConsol. Cases
`
`Source: In re Copaxone Consol. Cases, 2017 U.S. Dist. LEXIS 12168 at *82-83, 86 (D. Del. Jan. 30, 2017); Paper 57 at 4-5.
`
`NEPTUNE DX - 408
`
`
`
`Legal Authority
`In re CopaxoneConsol. Cases
`
`Source: In re Copaxone Consol. Cases, 2017 U.S. Dist. LEXIS 12168 at *92-94 (D. Del. Jan. 30, 2017); Paper 57 at 4-5.
`
`NEPTUNE DX - 409
`
`
`
`Legal Authority
`NovenPharm., Inc. v. Novartis AG
`
`Source: Noven Pharm., Inc. v. Novartis AG, IPR2014-00550, Paper 77 at 4 n.8; Paper 74 at 1.
`
`NEPTUNE DX - 410
`
`
`
`Legal Authority
`
`In re Wilson
`
`Source: In re Wilson, 311 F.2d 266, 268-69 (C.C.P.A. 1962); Paper 48 at 6.
`
`NEPTUNE DX - 411
`
`
`
`Legal Authority
`
`In re Hogan
`
`Source: In re Hogan, 559 F.2d 595, 605 & n. 17 (C.C.P.A. 1977); Paper 48 at 7.
`
`NEPTUNE DX - 412
`
`
`
`Legal Authority
`Ex Parte Erlich
`
`Source: Ex Parte Erlich, 1992 Pat. App. Lexis 2, *6 (Bd. Pat. App. & Interferences Jan. 16 1992); Paper 48 at 7.
`
`NEPTUNE DX - 413
`
`
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