CAS REGISTRY and CAS Registry Number FAQs
`
`What is CAS REGISTRYSM?
`What is a CAS Registry Number® (CAS RN®)?
`What does a CAS Registry Number look like?
`How does CAS assign Registry Numbers?
`What kinds of compounds does the CAS REGISTRY contain?
`How frequently is the CAS REGISTRY updated?
`Why have CAS Registry Numbers become the world standard?
`Why do regulatory agencies rely on CAS Registry Numbers?
`Where can I find CAS Registry Numbers?
`Why do some substances in CAS REGISTRY have zero associated
`references? How can I learn more about these substances?
`How can I obtain or request assignment of a CAS Registry Number?
`Why is it important to come to CAS for Registry Numbers?
`
`What is CAS
`REGISTRY?
`
`CAS REGISTRYSM is the most authoritative collection of
`disclosed chemical substance information, containing more
`than 122 million organic and inorganic substances and 66 million
`sequences (view current numbers).
`CAS REGISTRY covers substances identified from the scientific
`literature from 1957 to the present, with additional substances
`going back to the early 1900s.
`
`What is a CAS
`Registry
`Number (CAS
`RN)?
`
`Each CAS Registry Number® (CAS RN®) identifier:
`Is a unique numeric identifier
`Designates only one substance
`Has no chemical significance
`Is a link to a wealth of information about a specific chemical
`substance
`
`What does a
`CAS Registry
`Number look
`like?
`
`How does
`CAS assign
`Registry
`Numbers?
`
`What kinds of
`compounds
`does the CAS
`REGISTRY
`contain?
`
`A CAS Registry Number is a numeric identifier that can contain
`up to 10 digits, divided by hyphens into three parts.
`The right-most digit is a check digit used to verify the validity and
`uniqueness of the entire number.
`For example, 58-08-2 is the CAS Registry Number for caffeine.
`
`A CAS Registry Number is assigned to a substance when it
`enters the CAS REGISTRY database. Numbers are assigned in
`sequential order to unique, new substances identified by CAS
`scientists for inclusion in the database.
`
`CAS REGISTRY contains a wide variety of substances, including
`the world's largest collection of:
`Organic compounds
`Inorganic compounds
`Metals
`Alloys
`Minerals
`Coordination compounds
`Organometallics
`Elements
`
`ARGENTUM Exhibit 1085
` Argentum Pharmaceuticals LLC v. Research Corporation Technologies, Inc.
`IPR2016-00204
`
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`How
`frequently is
`the CAS
`REGISTRY
`database
`updated?
`Why have
`CAS Registry
`Numbers
`become the
`world
`standard?
`
`Why do
`regulatory
`agencies rely
`on CAS
`Registry
`Numbers?
`
`Where can I
`find CAS
`REGISTRY
`Numbers?
`
`Isotopes
`Nuclear particles
`Proteins and nucleic acids
`Polymers
`Nonstructurable materials (UVCBs)
`
`Approximately 15,000 new substances are added each day.
`See the most up-to-date CAS REGISTRY figures.
`
`Since CAS Registry Numbers are not dependent upon any
`system of chemical nomenclature, they can:
`Provide a reliable common link between the various
`nomenclature terms used to describe substances
`Serve as an international resource for chemical substance
`identifiers used by scientists, industry and regulatory bodies
`
`Chemical compounds can be described in many different ways:
`Molecular formula
`Structure diagram
`Systematic names
`Generic names
`Proprietary or trade names
`Trivial names
`A CAS Registry Number, however, is unique and specific to only
`one substance regardless of how many other ways the substance
`can be described.
`Governmental agencies have found CAS Registry Numbers ideal
`for keeping track of substances because
`They are unique
`They can be validated quickly and reliably
`They are internationally recognized
`
`Find CAS Registry Numbers in:
`SciFinder®
`STN® databases
`CAS publications
`Other publications
`Governmental regulatory agency commercial
`chemical inventories
`Selected Elsevier databases
`Handbooks, guides and technical reports
`Other printed reference works
`Chemical catalogs
`In a hurry? Contact CAS Registry Number Lookup Service and
`ask for 24-hour turnaround (Mon-Fri).
`
`Why do some
`substances in
`CAS
`REGISTRY
`have zero
`references?
`How can I
`learn more
`about these
`substances?
`
`Records in REGISTRY represent substances indexed for the
`CAS databases (CASM/CAplusSM, CASREACT®, CHEMCATS®,
`CHEMLIST®, MARPAT®) and other databases in products such
`as SciFinder® and STN®. Substances that come from sources
`other than literature or patent publications may not contain any
`references. CAS indexes these substances to support
`registration policies, chemical libraries, chemical catalogs, web
`sources, reaction databases and data collections not represented
`in STN.
`To learn more about a substance in REGISTRY that does not
`have any literature or patent references consult the Source of
`
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`

`
`How can I
`obtain or
`request
`assignment of
`a CAS
`Registry
`Number?
`Why is it
`important to
`come to CAS
`for Registry
`Numbers?
`
`Registration (SR) and Class Identifier (CI) fields in STN.
`
`CAS Client Services offers you several options for confirming and
`assigning CAS Registry Numbers and obtaining CA Index
`Names. Note that there is a fee associated with this service.
`
`While printed publications may contain outdated information, the
`CAS REGISTRY database is updated daily providing your best
`source for the latest CAS Registry Number information.
`CAS is the source and final authority for CAS Registry Numbers.
`Other resources may have associated an incorrect CAS Registry
`Number with a compound, and use of that incorrect CAS Registry
`Number in searches could lead you to irrelevant or inappropriate
`information.
`
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