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UNITED STATES PATENT AND TRADEMARK OFFICE
`
`BEFORE THE PATENT TRIAL AND APPEAL BOARD
`
`ARGENTUM PHARMACEUTICALS LLC, MYLAN
`PHARMACEUTICALS INC., BRECKENRIDGE PHARMACEUTICAL,
`INC., and ALEMBIC PHARMACEUTICALS, LTD.,
`Petitioners,
`
`v.
`
`RESEARCH CORPORATION TECHNOLOGIES, INC.
`Patent Owner
`
`Case IPR2016-002041
`Patent RE38,551 E
`
`Declaration of Dr. Binghe Wang
`
`ARGENTUM Exhibit 1217
`Argentum Pharmaceuticals LLC v. Research Corporation Technologies, Inc.
`IPR2016-00204
`
`1 Case IPR2016-01101, Case IPR2016-01242, and Case IPR2016-01245 have been
`joined with this proceeding.
`
`Page 00001
`
`

`
`I, Binghe Wang, do declare as follows:
`
`1.
`
`I am over the age of eighteen (18) and otherwise competent to
`
`make this declaration.
`
`2.
`
`I submit the present declaration to respond to particular points
`
`raised by the Patent Owner regarding certain exhibits referenced in my
`
`declaration.
`
`3.
`
`My background and qualifications are set forth in my Opening
`
`Declaration. My curriculum vitae was attached as an appendix to my Opening
`
`Declaration. I have reviewed that information, and it remains substantially the
`
`same and is still accurate. Exhibit 1002.
`
`4.
`
`Exhibit 1085 is webpage regarding the FAQs of CAS Registry
`
`Numbers that is referenced in my declaration, which was submitted in the
`
`above referenced IPR in conjunction with Petitioner’s Reply.
`
`5.
`
`Exhibit 1085 is a true and correct copy of the document obtained
`
`from the website of CAS, a Division of the American Chemical Society at:
`
`http://www.cas.org/content/chemical-substances/faqs.
`
`6.
`
`Having reviewed this document and this website, I have no
`
`reason to question the authenticity or accuracy of the above-listed exhibit.
`
`7.
`
`This document obtained from the CAS website contains
`
`2
`
`Page 00002
`
`

`
`information that appears accurate. Further, the exhibit is the type of document
`
`an expert in medicinal chemistry would typically consider when assessing the
`
`issues discussed in my declaration.
`
`8.
`
`Exhibit 1104 is a table summarizing the PI values of all of the
`
`FAA compounds mentioned in Dr. Kohn’s references. Exhibit 1218 is the
`
`amended version of Exhibit 1104, which now contains some PI values that
`
`were not included in the original exhibit. In Exhibit 1218, I have also
`
`corrected the PI values that the Patent Owner has listed as inaccurate. The
`
`values included in Exhibit 1218 and Exhibit 1104 are based on the data
`
`disclosed in the exhibits cited in my declaration and Dr. Roush’s declaration.
`
`9.
`
`I hereby declare that all statements made herein are true and that
`
`all statements made on information and belief are believed to be true; and
`
`further that these statements were made with the knowledge that willful false
`
`statements and the like so made are punishable by fine or imprisonment, or
`
`both, under Section 1001 of Title 18 of the United States Code.
`
`__________
`__
`Binghe Wang, Ph.D.
`
`3
`
`Page 00003

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