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`EXHIBIT 2004EXHIBIT 2004
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`www.bloodjournal.org
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`by guest For personal use only.on July 23, 2015.
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`CEPHALON, INC. -- EXHIBIT 2004
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`71 33 Fludarabine
`71 33 Fludarabine
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`103 (cid:9)
`63 Fludarabine + Prednisone
`
`p= .06
`= .06
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`4-
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`0 12 24 36 48 60 72 84 96 108 120 0 12 24 36 48 60 72 84 96 108 120
`MONTHS
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`CEPHALON, INC. -- EXHIBIT 2004
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`by guest For personal use only.on July 23, 2015.
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`CEPHALON, INC. -- EXHIBIT 2004
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`by guest For personal use only.on July 23, 2015.
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`www.bloodjournal.orgFrom
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`CEPHALON, INC. -- EXHIBIT 2004
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`www.bloodjournal.orgFrom
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`by guest For personal use only.on July 23, 2015.
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`CD4
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`ABSOLUTE CD4 and CD8 COUNT/ pi
`ABSOLUTE CD4 and CD8 COUNT/ pi
`
`
`0 3 6 12 18 24 >24 (cid:9)0 3 6 12 18 24 >24 (cid:9)
`
`0 3 6 12 18 24 >24 0 3 6 12 18 24 >24
`
`MONTHS (±3 ► SINCE START OF FLUDARA MONTHS (±3 ► SINCE START OF FLUDARA
`
`lEE 25%-75%
`lEE 25%-75%
`
`q Median value q Median value
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`⬍
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`⫹
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`⬍ ⬎
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`CEPHALON, INC. -- EXHIBIT 2004
`
`(cid:9)
`(cid:9)
`
`
`
`
`www.bloodjournal.orgFrom
`
`
`
`
`
`by guest For personal use only.on July 23, 2015.
`
`
`
`⫹
`
`
`
`CEPHALON, INC. -- EXHIBIT 2004
`
`
`
`
`
`
`www.bloodjournal.orgFrom
`
`
`
`by guest For personal use only.on July 23, 2015.
`
`
`
`
`
`CEPHALON, INC. -- EXHIBIT 2004
`
`
`
`From
`
`www.bloodjournal.org
`
`
`
`
`
`by guest For personal use only.on July 23, 2015.
`
`
`
`ood
`ood 1998(cid:160)92: 1165-1171
`
`(cid:160)(cid:160)
`
`(cid:160)
`Long-Term Follow-Up of Patients With Chronic Lymphocytic Leukemia
`CLL) Receiving Fludarabine Regimens as Initial Therapy
`
`(cid:160)(
`
`M.J. Keating, S. O'Brien, S. Lerner, C. Koller, M. Beran, L.E. Robertson, E. J Freireich, E. Estey and H.
`Kantarjian
`
`Updated information and services can be found at:
`http://www.bloodjournal.org/content/92/4/1165.full.html
`Articles on similar topics can be found in the following Blood collections
`
`
`(cid:160)(cid:160)(cid:160) (4137 articles)Clinical Trials and Observations
`
`Information about reproducing this article in parts or in its entirety may be found online at:
`http://www.bloodjournal.org/site/misc/rights.xhtml#repub_requests
`
`Information about ordering reprints may be found online at:
`http://www.bloodjournal.org/site/misc/rights.xhtml#reprints
`
`Information about subscriptions and ASH membership may be found online at:
`http://www.bloodjournal.org/site/subscriptions/index.xhtml
`
`Blood (print ISSN 0006-4971, online ISSN 1528-0020), is published weekly by the American Society of
`Hematology, 2021 L St, NW, Suite 900, Washington DC 20036.
`Copyright 2011 by The American Society of Hematology; all rights reserved.
`(cid:160)
`
`CEPHALON, INC. -- EXHIBIT 2004
`
`
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