`
`PROTOCOL NUMBER:
`
`109MS30 1
`
`STUDY PHASE:
`
`3
`
`·-
`
`I
`1·
`I
`I
`
`14 Cambridge Center
`Cambridge, MA 02142, USA
`TEL: 1-6 17-079-2000
`FAX: 1-617-079-3518
`
`5200 Research Place
`San Diego, CA 921 22, USA
`TEL: 1-858-401-8500
`FAX: 1-858-401-8750
`
`Thames House
`Foundation Park
`Maidenhead, Berkshire SL6 3UD
`United Kingdom
`TEL: 44-1628-501000
`FAX: 44·1628·501010
`
`PROTOCOL TITLE:
`
`A Randomized, Multicenter, Double-Blind, Placebo(cid:173)
`Controlled, Dose-Comparison Study to Determine the Efficacy
`and Safety ofBG00012 in Subjects with Relapsing-Remitting
`Multiple Sclerosis
`
`EUDRACTNO:
`
`2006-003696-12
`
`DATE:
`
`24 October 2006
`Version 2
`FINAL
`
`I approve this document in accordance with Biogen Idee's
`current policies and procedures
`
`•
`
`Carmen Bozic, Vice President
`Drug Safety and Risk Management, Biogen Idee
`
`CONFIDENllAL
`The information contained herein may not be used. disclosed, or published without the written consent ofl3iogen Idee Inc.
`I
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`Biogen Exhibit 2230
`Coalition v. Biogen
`IPR2015-01993
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