`
`PROTOCOL NUJViBER:
`
`l09MS30l
`
`STUDY PHASE:
`
`3
`
`14 Cambridge Center
`Cambridge, MA 02142, USA
`TEL: 1-617-679-2000
`F .AX: 1-617 -679·3518
`
`5200 Research Place
`San Diego, CA 92122, USA
`TEL: 1-858-401·8500
`FAX: 1-858-401 · 8750
`
`Thames House
`Foundation Park
`Maidenhead, Berkshire SL6 .3UD
`United Kingdom
`TEL: 44-1628-501000
`FAX : 44·1628-501010
`
`PROTOCOL TITLE:
`
`A Randomized, Multicenter, Double-Blind, Placebo(cid:173)
`Controlled, Dose-Comparison Study to Detennine tbe Safety
`and Efficac~' of DOOOO 12 in Subjects with Relapsing·
`Remitting Multiple Sclerosis
`
`EUDRACTNO:
`
`2006-003696-12
`
`DATE:
`
`21 September 2006
`Ver.sion l
`FINAL
`
`1 approve this document in accordance with Siogen Idee's
`current polictes and procedures
`
`'""~ ~~ !.A£)
`
`Carmen Bozic. Vice P1estdent
`Orug Safely end Risk Managern.ent Biogen Idee
`
`~)- d-1 1 "2-oo 6 .
`
`Date
`
`CONPIDENTIAL
`11le ioformal.jon oomained hereit111la) not be used, dillclused. or published '' ithouL the wriucn cw1~ent ofBiogcJ) ld~~ Inc.
`I
`
`Page 1 of94
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`Biogeo Exhibit 2229
`Coalition v. Biogeo
`IPR2015-01993
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