`(numbers provide the date of the month on which a given range either began or ended)
`
`Daily* Dosing Date Ranges
`
`M
`
`mmj
`2007
`
`2008
`
`P00012-04-06 (6-month rat study)
`See Ex. 2273 at1,10,16
`
`P00012-04-11 (2-year rat study)
`See Ex. 2375 at 18; Ex. 2274 at 1, 10, 20
`
`C-1900 (Phase II clinical Trial)
`See Ex. 2312 at 27; Ex. 2092 at 1, 5, 23, 24
`
`P00012-05-03 (2-year mouse study)
`See Ex. 2375 at 26; Ex. 2377 at 1, 10, 18, 19
`
`P00012-05-05 (11-month dog study)
`See Ex. 2275 at1,9, 14-16
`
`P00012-05-08 (1 -year monkey study)
`See Ex. 2276 at 1, 9-11
`
`*
`
`Due to inclement weather, animals in Study Nos. P00012-04-06 and P00012-04-11 were not dosed on either December 23, 2004 or
`January 6, 2005, and animals in Study No. P00012-05-03 were not dosed on Feb. 14, 2007.
`
`** Daily dosing for P00012-04-06 (6 month rat study) began on Aug. 17, 2004
`
`Page 1 0‘ 1
`
`- Human Phase II & III Clinical Trials
`
`- Non-Clinical Animal Studies
`
`Biogen Exhibit 2033
`Coalition v. Biogen
`IPR2015—01993
`
`
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