CFAD v. Anacor, IPR2015-01776
`ANACOR EX. 2015 - 1/3
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`Senior Managing Editor: Maureen Barlow Pugh
`Managing Editor: Barbara Werner
`New Terms Editor: Thomas W. Filardo, MD
`Copy Editors.’ Peter W. Binns, Linda G. Francis, Raymond Lnkens, Bonnie Montgomery
`Ct‘n‘ef0n-Line Editor: Barbara L. Ferretti
`Orr-Line Editors: Kathryn J. Cadle, Dana Workman
`Proofreaders: Peter W. Binns; David A. Bloom, MD; Alfred J. Bullet, MD; Ted Burk; Regina Lavette
`Davis; John A. Day, Jr., MD, FCCP; Richard Diamanti; John H. Dirckx, MD; Thomas
`W. Filardo, MD; Linda G. Francis; John M. Last, MD, FRACP, FRCPC; Raymond
`Lukens; Kate Mason, CMT; Joan Sarchese
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`A rt Director." Jonathan Dimes
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`Mikki Senkarik, Michael Schenk, Larry Ward
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`Design: Dan Pfisterer
`
`Copyright © 2000 Lippincott Williams & Wilkins
`351 West Camden Street
`Baltimore, Maryland 21201-2436 USA
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`
`Copyright © by William Wood and Company: 1911, lsted.; 1912, 2nd ed.; 1914, 3rd ed.; i916, 4th ed.;
`1918, 5th ed.; 1920, 6th ed.; 1922, 7th ed.; 1924, 8th ed.; 1926, 9th ed.; I928, 10th ed.; 1930, I 1th ed.
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`Copyright © by Williams & Wilkins: 1933, 12th ed.; 1935, 13th ed.; 1939, 14th ed.; 1942, lSth ed.; 1946,
`16th ed.; 1949, l7th ed.; 1953, 18th ed.; 1957', 19th ed.; I961, 20th ed.; 1966, 21st ed.; l9'F2, 22nd ed.;
`1976, 23rd ed.; 1982, 24th ed.; 1990, 25th ed.; 1995, 26th ed.
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`All rights reserved. This book is protected by copyright. No part of this book may be reproduced in any
`form or by any means, including photocopying, or utilized by any information storage and retrieval sysw
`tern without written permission from the copyright owner.
`
`Stedrmm '3 is a registered trademark of Lippincott Williams 8: Wilkins.
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`The publisher is not responsible (as a matter of product liability, negligence or otherwise) for any injury
`resulting from any material contained herein. This publication contains information relating to general
`principles of medical care which should not be construed as specific instructions for individual patients.
`Manufacturers‘ product information and package inserts should be reviewed for current information, in-
`cluding contrainclications, dosages and precautions.
`
`Database design by Lexi—Comp Inca, Hudson, OH
`Printed in the Urttted States afAmerico by World Cotor. Inc:
`
`Library of Congress Cataloging-in-Publication Data
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`Stedman, Thomas Lathrop, 1853-1933.
`Stedrnan's medical dictionary.—2Tr'th ed.
`p.; cm.
`ISBN 0—683—40007-X (regular)—lSBN 0-683-40008-3 {deluxe}
`l. Medicine—Dictionaries.
`I. Title: Medical dictionary.
`1!. Title.
`[DNLM:
`l. Mcclieine—Dictionary—English. W 13 S8l2m I999]
`Rl2l .S3 l999
`6 1 0’ .3—dc2 I
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`99-056094
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`000102030405
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`ANACOR EX. 2015 - 2/3
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`recorded increase in skin temperature (feedback) ind
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`specific thought complex or action has produced the d
`iological response.
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`icatfis
`eSifed
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`Pm
`EMG b., a form of b. that uses an electromyographic m
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`muscle tension as the physical symptom to be deconditiu ea‘!-I
`as tension in the frontalis muscle in the head which ‘led.-'
`headaches.
`can or
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`biofla-vo-noids (bi—o-fliiv’on-oydz).
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` “[1115
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`having the activity of the so—called vitamin P, notam), run _'
`esculin.
` Jtley
`bi~0-gen-(3-sis (bi-ft-jen’é-sis).
`1. Term given by H“
`3' and
`principle that life originates from preexisting life am
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`from nonliving material. SEE spontaneous generation, we _
`tion rhea:-_\s, 2. SYN l‘Il(I.‘§_\-'Il|l'IC.‘ilS.
`[bio- -I— G. genesis, m.ig.:'P1
`
`mitochondrial b., the process by which I'l'tll0CI1IJnd[-ja i
`their ability to make adenosine triphosphate by synthesizin
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`3
`tional respiratory enzyme complexes.
`biogenet-ic (bi"6—je—net’ik). Relating to biogene5i5_
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`bi-o~gel't-ic (bi’t'i-jen-ik). Produced by a living organism
`bi-o-ge-o-chem-islry (bT'o—jé—6-kem’is—tre). The studs;
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`influence of living organisms and life processes on the ch:
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`structure and history of the earth.
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`bi-ovgrav-ics (bi-o-grav'iks). That field of study dealing wt"
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`effect on living organisms (particularly humans) of
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`gravitational effects produced. e.g.. by acceleration or by frag
`in the former case, heavier than normal weight is induced‘ '
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`the latter weightlessness. [bio- + L. gravis, weight]
`bioinfonnatics. A scientific discipline encompassing 3]]
`of biologic information acquisition, processing. storage, '..-1.5
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`tion, analysis, and interpretation that combines the tools an ‘
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`niques of mathematics, computer science, and biology "wt
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`aim of understanding the biologic significance of a v‘ "
`data.
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`hioaeoustics
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`204
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`effects of sound fields or mechanical vibrations on living orga-
`nisms.
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`bioaetive (bi'EI—:‘ik'tiv). Referring to a substance that can be
`acted upon by a living organism or by an extract from a living
`organism.
`hi-0-as-Say (bi-o-as’a). Determination of the potency or concen-
`tration of a compound by its effect upon animals, isolated tissues,
`or microorganisms. as compared with an analysis of its chemical
`or physical properties.
`bi-o-as-tro-nau-ties (bi’o—as—tr6-naw’tiks). The study of the ef-
`fects of space travel and space habitation on living organisms.
`bi-o~a~vail-a-biI~i-ty (bro-a-val’a-biI’i—te).
`The physiological
`availability of a given amount of a drug. as distinct from its
`chern.ica[ potency; proportion of the administered dose which is
`absorbed into the bloodstream.
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`lJi~0~bllr-den (bi’t'J-ber’den). Degree of microbial contamination
`or microbial load: the number of microorganisms contaminating
`an object.
`bi-0-cat-3-Iyst {bi‘r‘J—kat—£i—list). A substance of biologic origin
`that can catalyze a reaction: e.g., an enzyme.
`bivovce-no-sis (bi-6-se-no’sis). An assemblage of species living in
`a particular biotope. s\'N biotic community.
`[bio- + G.
`.Ii(UfIir).\‘,
`common]
`bi-ochem-i-eal {bi—6—kem’i—kfil). Relating to biochemistry.
`bi-oehem-isttry (bT—6—kem’is—tre). The chemistry of living orga-
`nisms and of the chemical, molecular. and physical changes oc-
`curring therein. SYN biologic chemistry, physiologic chemistry.
`bi-0-chem-DI'~phic (bi'o-kem-or'fik). Denoting the relationship
`between biologic action and chemical structure, as in food and
`drugs.
`bi-o-chrome (bra-kram).
`cltrorrm, color]
`bivovcidial (bi—o—si’dal). Destructive of life: particularly pertaining
`to microorganisms. [bio- + L. made. to kill]
`bivt]-cli-ma-tol-0-gy (bT‘o—kli—mii—tol’6—jE). The science of the re-
`lationship of climatic factors to the distribution, numbers. and
`types of living organisms: an aspect of ecology.
`bioeompatibility {bi'6—kom—pat-i-bil'i-té). The relative ability of
`a material to interact favorably with a biological system. [bio- +
`compatibility]
`bi-ovcy-bet’-net-its (bi‘o—si—ber—net’iks), The science of commu-
`nication and control within it living organism, particularly on a
`molecular basis.
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`SYN natural
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`,r::',i,-:ru':rr.
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`[bio- + G.
`
`biocy-tin (bi—o—si’tin). E-N~Biotinyl-L-lysine; biotin condensed
`through its carboxyl group with the 8—amino group of a lysyl
`residue in the apoenzymes to which biotin is the coenzyme; the
`predominant linkage in which biotin is found. svn biotirtyllysine.
`bi-0-cytinvase (bi-6-si’tin-as). An enzyme in blood that catalyzes
`the hydrolysis of biocytin to biotin and lysine (or, lysyl residue if
`die lysine is in a protein).
`bi-o-de-gradtatble (bi’6-de-grz'td’a-bl). Denoting a substance that
`can be chemically degraded or decomposed by natural effectors
`(e.g., weather, soil bacteria, plants, animals).
`bio-de-gra-dattion. SYN hintr:insforIn:Ition.
`bi-o-dy-nam-ic (bi'o—di—nam’ik). Relating to biodynamics.
`bi-o-dy-nam-ics (bi’o—di~nam’iks). The science dealing with the
`force or energy of living matter. [bio- + G. d_vmtmr'.r. force]
`bi-o-e-cology (bi—6—E—koI’o—je).
`svm ccr.:lo:__-_y.
`bi-o-el-entent (bi'o—el’é~tnent). An element required by a living
`organism.
`1. The study of energy
`bi-oen-er-get-ies (bi'fi—en-er-jet’iks).
`changes involved in the chemical reactions within living tissue. 22
`The study of energy exchanges between living organisms and
`their environments.
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`bi-0-En~gi-neer-ing (bT'o—en—jin—ér’ing). SEE biomedical c.rr_r,rinr'er—
`mg.
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`bivovfeed-back (bi-6-fed'hak). A training technique that enables
`an individual
`to gain sortie element of voluntary control over
`autonomic body functions; based on the teaming principle that a
`desired response is learned when received information such as a
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`hl'0‘iII‘SlI‘l.l'l'I'lEl:III (bI"'6—in’stroo-ment). A sensor or dew‘
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`ally attached to or embedded in the human body or other
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`animal to record and to transmit physiologic data to a -.
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`and monitoring station.
`bi~0~ki-net-ics (bi‘o-ki-net’iks). The study of the growthe
`and movements that developing organisms undergo. [bi
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`king‘-.ri'.i-, motion]
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`bi-o-log-ic, bi-o-lug-i-cat (bi’r':-loj’ik, -loj’i—ldSl). Relating
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`ogy.
`bi-ol-o-gist (bi—ol'6—jist). A specialist or expert in biology.
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`bi-ol-o»gy (bi—ol'o—jé). The science concerned with the ph
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`of life and living organisms. [bio- + G. logos. study]
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`cellular b., svm L-_vmIugy_
`molecular b., study of phenomena in terms of b. mole
`chemical) interactions: traditionally, the focus of molecul
`more specific than biochemistry in that it has an emph
`chemical
`interactions involved in the replication of D
`“transcription“ into RNA, and its "translation" into or ex
`in protein. i.e., in the chemical reactions connecting geno
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`phenotype.
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`oral b., that aspect of b. devoted to the study of biologl
`nomena associated with the oral cavity in health and di5°“.
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`dental caries, mastication. periodontal disease).
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`pharmaceutical b.. SYN pIiai'ni:nc0gI1osy.
`.
`radiation b., field of science that studies the biological " .
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`ionizing radiation.
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`bi»ovlu-mi-nes-certee {bi’(’)—loo—min—es’ens). 1. Li ght P’°d-
`cerlain organisms from the oxidation of Iuciferins Imp"
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`action of luciferases and with negligible production.-
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`chemical energy being converted directly into light 9"
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`cold light { I ). 2. Any light produced by a living orgill1l5“'
`L. imtten {~r‘a.".r), light]
`E‘.E."
`bi-Olvy-sis {bT—ol’i—sis). Disintegration of organic Infill?‘
` + C3 -r-:
`the chemical action of living organisms. [bio-
`lion]
`[bT—fi-lit’ik).
`bi-0-lyt-it:
`destroying life.
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`l. Relating to biolysis. 2- Ca
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`ANACOR EX. 2015 - 3/3