DECLARATION or ARTHUR RIGGS
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`15
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`m -rm-: tmm-.n sr/was PATENT AND TRADEMARK -ctrrzcs
`sax»-one -ms aonnn or rm-ran-r APPEALS AND um-smrmzwcss
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`lnterrerenee No. 102.572
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`Exlminenin-Cltief
`Mary F. Domtey
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`3 )
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`Cabilly at
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`ll
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`v.
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`Bou et al
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`Efl&Afl
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`1.
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`I. Arthur Riggs. declare end state that
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`I am a citizen of the United States
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`residing in LaVemc.. Callfornln. My Cur:-lculttm Vilne is attached It Cehilly et el
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`I an I co-inventor of the United States Pllent 4.816.361 entltled
`Exhibit No. 1.
`ltnmunoglobultn Prepu-atlone'.
`I
`‘Recombinant
`2.
`I hve been employed by the City of Hope in Duerte. Cllifomle from
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`June I969 to the present as Director. Department of Blology.
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`‘
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`3-
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`Dmin! the period of July 1980 through September 1980.
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`I was at
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`Geoenteeh on etbbotleel
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`from the City of Hope. My lntentlou was to explore the
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`‘- ponibllity of producing Antibodies in bnetedn. Alter my say at Geumeeh.
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`I
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`returned to the City of Hope where l
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`formulated 1 propoul whereby Oenenteoh would
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`gum in the funding of this pro}eet (cebilly Exhibit No. 2).
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`The pyopengl was bend in
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`l zubmtttott
`part on eonverutlons between Dr." Heynokcr. slmmel Cebilly the mraelf.
`shit proposal
`for revlew by Genentooh on October 5. 1981.
`Included in this propoeel
`wu : research plea for
`the cloning. bectetlel expression. and tltet-mien of both
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`heavy and light ehlitt genes
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`from a monoclonal
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`tntibody direetett
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`cg-duet humus
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`cerclnoembryonie antigen (CEA).
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`Ftmlterrnot-e.
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`I
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`suggested in the. proposal
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`that
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`(Cebllly Exhibit No. 2. Bite: No. 00922) a single bgcterlgl gt;-gln could be’ ebnltnteted.
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`which oonttlnetl both heavy and llght eheln genes
`dltcuued during our earlier convenntlons,
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`for co-expreeeiatt. an idea
`V
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`-4.
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`My experimental plan included the coluboratlon of Dr. Shmtrel Cabilly.
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`fellow in my laboratory M the City of Hope. end Dr.
`a post doctoral
`5 Senior Scientist at Genentech.
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`t-Ierbert Heynelzer.
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`GNE-MED-02012
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`GNE—CSK0000’341 5
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`GNE-HGS 00082026
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`SANOFI v. GENENTECH
`SANOF1 V~ GENENTECH
`IPR2015-01624
`IPR2015-01624
`EXHIBIT 2026
`EXHIBITZOZ6 GNE-REG00080759
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`GNE-LILLY-BMS oooso75
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`.
`DECLARATION OF ARTHUR RIGGS
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`‘
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`16
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`lahn Shiveli “'55 15¢-C5‘? 01'
`I discussed this propcsed project with Dr.
`S.
`Hope. who was involved in the’ study of and-CEA antibodies.
`I 1-equated hum him a
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`hybridoml. cefl
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`tine that expressed lhcst‘. antibodies.
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`2
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`received this 69" 1130
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`(CE.A.65-E3) on or about February. 1981.
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`5.
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`During the period of these studies 1 worked clasely with Dr. Csbllin who
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`wax undct my dim: supervisien.
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`In addition.
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`I maintained regulu contact with Dr.
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`Heyneker.
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`_
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`_
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`7.
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`I further dectare that all statements made of my 0% 1=M'‘''¢4I¢ 499 ‘N’
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`and that all statements made on information and belief are believed 16 be tune: and
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`further um these suxemenzs were met}: with the knovledte that willhll mu
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`statement: and the like :6 and»: are punishable by fine or
`under Section 1001 of Tm: 28 of the United sates Code.
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`imprisonment. or both.
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` nma:
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`/_",Z.2fA/2}’
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`GNE-MED-02013
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`GNE—(GSKOO0()'3416
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`GNE-HGS 00082027
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`GNE-LILLY-BMS 00080760
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`GNE-REG00080760