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` Vessel Sealing /j
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`Consistent, Reliable, Trusted Vessel Sealing
`
`Since irsinrioouciion tolhe martrelin 1993, Ligasure" technologyhassetlhe industry
`standard brvesel sealing. 1'hetechnology hasbeen used in more than 10 million
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`procedures worldwide. and issupporhd by an ever-growing bodyotevidence-based
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`The clinical ellicacy, consistency and reliability orLigaSure"' pmduds is delivered through
`a variety of instruments for use in both laparoscopir: and open procedures.
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`Ligasure" Technology - Delivering Pertomrance Beyond Expectations
`Across the range ofproducts and procedures, LigaSure"'
`technology delivers a unique corrbination of pressure and
`energylo create a consistent seal with each application.
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`Get M079 '"f°"“ati°"
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`C ontact A Rep
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`- Provides a combination otpressure and energy It create
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`o Pemranentty luses vessels up to and including 7 mm in
`diameterand tissue bundles withoutdissection or isolation " ]
`- Average seal cycle is 2 to 4 seconds, when used with the
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`ForceTn‘ad"' energy platform
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`- sealswithstandlhreetimesnormalsystoliclnood pressure
`. Feedback-controlled response system aubmatically dlscontinues energy delivery when the seal
`cycle is complete, eliminating the guesswork
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`Ligasurem instruments have been found to:
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`. Have the highest burst pressure, tasuast sealing time and were highest rated overall compared b
`Gyms PK""', Hamronic AcE"" and ENSFJL ""‘
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`. Reduce blood loss compared to sutures and clips
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`Access 3 dmica. Wblicamn mat compares
`Ligasure" technology to three other vessel sealing
`technologies.
`
`. Reduce procedure ime compared to sutures”
`. Reduce patient length otstay compared b sutures 3
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`[ Learn More 1
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`compared 10 mechanical ligation techniques, Ligasure“ IGCIIIIOIOQY has been shown
`10:
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`. significantly reduce operative blood loss in coloiectal, gynecologic and urologic surgery “
`0 Significantly reduce perioperative N000 ll3fISlIlSlOfl5 in gynecologic, urologic and general surgery ‘
`II II
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`. significantly reduce procedure time in coloredal, gynecologic and urologic surgery '~°~’-9- '1 '3
`. significantly reduce length of hospital stay in gynecologic and urologic surgery ‘* ”
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`compared to other energy-based modalities, Ligasure“ technology has been shown
`to:
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`o significantly reduce operative blood loss in colorectal and gynecologic surgery ‘“7
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`. Significantly reduce procedure lime in colorectal and gynecologic surgery “- "
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`What is ‘I'issueFect“‘ sensing IOCIIIIOIOIIV?
`Page 1 of3
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`TissueFect™ sensing technology is the control system for the ForceTriad™ energy platform, designed to
`precisely manage energy delivery, creating a range of options for desired tissue effect. TissueFect™ sensing
`technology monitors changes in tissue impedance 3,333 times a second, and adjusts energy output
`accordingly to deliver the appropriate amount of energy for the desired tissue effect.
`What is LigaSure™ tissue fusion?
`
`LigaSure™ vessel sealing technology has been updated and improved in the ForceTriad™ energy platform,
`controlled by TissueFect™ sensing technology. LigaSure™ tissue fusion, like LigaSure™ vessel sealing, uses
`the body’s own collagen and elastin to create a permanent fusion zone. This technology can fuse vessels up to
`and including 7 mm, lymphatics, tissue bundles and pulmonary vasculature, and has an average seal cycle of
`two to four seconds in most surgical situations.
`
`1 Lamberton GR, Hsi RS, Jin DH, Lindler TU, JellisonFC, Baldwin DD. Prospective comparison of four laparoscopic vessel ligation
`devices. J Endourol. 2008;22(10):2307­2312.
`
`2 Ding Z, Wable G, Rane A. Use of LigaSure bipolar diathermy system in vaginal hysterectomy. J Obstet Gynaecol. 2005;25(1):
`49­51.
`
`3 Levy B, Emery L. Randomized trial of suture versus electrosurgical bipolar vessel sealing in vaginal hysterectomy. Obstet
`Gynecol. 2003;102(1):147­151.
`
`4 Targarona, et al. A prospective randomized comparison of conventional electrosurgery, biopolar computer­controlled
`electrosurgery and ultrasonic dissection. Operative Outcome and Cost analysis. Surgical Innovation. 2005 Dec;12(4):339­344.
`
`5 Manouras, et al. Sutureless open low anterior resection with total mesorectal excision for rectal cancer with the use of the
`electrothermal bipolar vessel sealing system. 2007. Med Sci Monit; 13(5): CR224­230.
`
`6 Ding Z, et al. Use of LigaSure bipolar diathermy system in vaginal hysterectomy. Journal of Obstetrics Gynaecology. 2005
`Jan;25(1):49­51.
`
`7 Levy B, Emery L. Randomized Trial of Suture Versus Electrosurgical Bipolar Vessel Sealing in Vaginal Hysterectomy. Obstetrics
`and Gynecology. 2003 Jul;102(1):147­151.
`
`8 Tamussino K, et al. Electrosurgical bipolar vessel sealing for radical abdominal hysterectomy. Gynecologic Oncology. 2005 Feb;
`96(2):320­322.
`
`9 Leonardo C, et al. Laparoscopic nephrectomy using LigaSure system: preliminary experience. Journal of Endourology. 2005
`Oct;19(8):976­8.
`
`10 Daskalopoulos G et al. Electrothermal bipolar coagulation for radical prostatectomies and cystectomies: a preliminary case­
`controlled study. International Urology and Nephrology. 2004;36(2):181­185.
`
`11 Romano F, et al. Laparoscopic Splenectomy: LigaSure versus EndoGIA: A Comparative Study. J Laparoendoscopic & Adv
`Surg Techniques. 2007. Vol. 17, No. 6.
`
`12 Cronje HS, et al. Electrosurgical bipolar vessel sealing during vaginal hysterectomy. Int J Gynaecol Obstet. 2005 Dec;91(3):243­
`5.
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`13 Metzelder ML, et al. Laparoscopic nephroureterectomy in children: a prospective study on LigaSure versus Clip/Ligation. Eur J
`Pediatr Surg. 2006 Aug;16(4):241­4.
`
`14 Araki Y, et al. Clipless hand­assisted laparoscopic total colectomy using LigaSure Atlas. Kurume Medical Journal.
`2004;51(2):105­8.
`
`15 Campagnacci R, et al. Electrothermal bipolar vessel sealing device vs. ultrasonic coagulating shears in laparoscopic
`colectomies: a comparative study. Surg Endosc. 2007 Feb 8.
`
`16 Takada et al. Comparative study of electrothermal bipolar vessel sealer and ultrasonic coagulating shears in laparoscopic
`colectomy. Surgical Endoscopy. 2005;19:226­228.
`
`17 Demirturk F, et al. Comparison of the use of electrothermal bipolar vessel sealer with harmonic scalpel in total laparoscopic
`hysterectomy. J Obst Gynaecol Res. 2007; 33 (3):341­345.
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