William B. Trattler, MD
`
`The Center for Excellence in Eye Care
`8940 North Kendall Drive, Suite 400E
`Miami, Florida 33176
`(305) 598-2020
`wtrattler@gmail.com
`NPI # 1093730996
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`CERTIFICATION
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`10/98
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`EDUCATION
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`7/96-7/97
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`7/93- 7/96
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`7/92-6/93
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`9/88-5/92
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`9/84-6/88
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`EMPLOYMENT
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`7/97-Present
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`7/02-7/06
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`7/97-7/01
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`1/1/2009:
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`BOARD CERTIFIED IN OPHTHALMOLOGY
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`Recertified (expires 12/31/2018)
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`UNIVERSITY OF TEXAS- SOUTHWESTERN MEDICAL SCHOOL, Dallas, Texas
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`Cornea and External Disease Fellowship
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`UNIVERSITY OF PENNSYLVANIA/ SCHEIE EYE INSTITUTE
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`Ophthalmology Residency
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` MOUNT SINAI MEDICAL CENTER, Miami Beach, Florida
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`Internal Medicine Internship
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`UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, Miami, Florida
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`M.D. Degree with Research Distinction
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`DARTMOUTH COLLEGE, Hanover, New Hampshire
`Bachelor of Arts in Biology, cum laude
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`THE CENTER FOR EXCELLENCE IN EYE CARE, Miami, Florida
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`Private Practice; Subspecialty: Cornea, External Disease, & Refractive Surgery
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`BASCOM PALMER EYE INSTITUTE; Miami, FL (3 half days per month)
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`Supervised Residents in the Bascom Palmer Eye Emergency Department
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`Instructed residents in anterior segment surgery (cataract and corneal surgery)
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`V.A. HOSPITAL, Miami, Florida
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`Surgical Staff: Supervising University of Miami ophthalmology residents in surgery & clinic
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`ACADEMIC APPOINTMENTS
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`1/2012-Present
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`7/2000-Present
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`Volunteer in the Department of Ophthalmology, Herbert Wertheim College of Medicine,
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`Florida International University
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`Volunteer Assistant Professor of Ophthalmology, Bascom Palmer Eye Institute
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`AWARDS AND HONORS
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`November 2013
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`Senior Achievement Award, American Academy of Ophthalmology
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`Jan 9, 2012
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`Best Paper of Session, 6th Annual International Military Refractive Surgery Symposium; Jan 2012
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`1
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`PAGE 1 OF 36
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`SENJU EXHIBIT 2051
`LUPIN v SENJU
`IPR2015-01100
`
`

`
`William B. Trattler, MD
`
`Best Paper of the Day, Hawaiian Eye 2012 Meeting; Maui, Hawaii; Jan 2012
`
`PS250: Identified by the publishers and editors of Premier Surgeon as one of the 250 top innovators
`in premium IOL implant surgery.
`
`Chief Medical Editor, Advanced Ocular Care
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`website: http://bmctoday net/advancedocularcare/
`
`Jan 2012
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`
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`4/10
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`1/10 to present:
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`4/09 to present:
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` Medical Editor: Eyetube net.
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`
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`4/09
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`
`12/07 to 7/2013
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`11/06
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`05/06
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`04/06
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`Best Paper of Session; Quantitative Measurement of Accommodation in Phakic Eyes with a Wavefront
`Aberrometer; ASCRS 2009
`
`Trusted LASIK Surgeons: Qualified and Listed at Trusted LASIK Surgeons, a LASIK directory service
`that screens surgeons based on experience, premier patient care, and professional credentials
`
`Poster 664: Delayed Epithelial Healing With Nepafenac Ophthalmic Solution was “selected as one of the
`best posters at the 2006 Meeting of the American Academy of Ophthalmology”, Las Vegas, NV; Nov 13
`2006
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`Achievement Award; American Academy of Ophthalmology
`
`Top 50 Cataract & Refractive Surgery Opinion Leaders, as voted on by readers of Cataract & Refractive
`Surgery Today.
`
`2006, ‘08-11, ‘13-14 Aspen Invitational Refractive Symposium: Ski Race Champion
`
`2002
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`Curtis D. Benton, Jr., MD Outstanding Young Ophthalmologist Leadership Award; This award is
`presented by the Florida Society of Ophthalmology (FSO) to a Florida ophthalmologist who has
`demonstrated leadership, service, competence and devotion to the high ethical and professional standards
`of the FSO.
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`1993-94 & 1995-96 Scheie Eye Institute Teaching Award
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`1994
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`1991
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`1989
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`Walter Stark, MD Award: “First Place Downhill Racer”, Current Concepts in Ophthalmology meeting,
`Vail, Colorado
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`Alpha Omega Alpha, Medical Honor Society
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`John H. Fomon Memorial Research Fellowship, American Cancer Society: Support for ocular
`immunology research
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`1987
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`Raynolds Expedition Fund Grant: Supported shark research in Bimini, Bahamas
`
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`RESEARCH POSITIONS/CLINICAL TRIALS
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`01/11 to 04/11
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`Insite Vision protocol C-10-303-001: Randomized Double Masked 14 day Study to Compare ISV-303
`(0.075% Bromfenac in Durasite) to Vehicle and Xibrom in Post Cataract Surgery Volunteers.
`
`07/10 to present
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`Corneal Collagen crosslinking with riboflavin for Keratoconus, Pellucid, RK, and Post-LASIK ectasia in
`patients as young as 12 years old; Sponsored by CXLUSA
`
`07/10 to present
`
`Multicenter Comparison of Tecnis Multifocal One Piece IOL to Restor D1 Multifocal Intraocular Lens;
`Sponsored by Abbott Medical Optics
`
`07/10 to present
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`Multicenter, Randomized, Masked Comparison of Bromfenac and Besifloxacin BID with Either
`Prednisolone BID or Loteprednol 0.5% BID for Prevention of Retinal Thickening and CME Following
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`2
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`PAGE 2 OF 36
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`

`
`William B. Trattler, MD
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`Phacoemulsification; Unrestricted Grant provided by Bausch and Lomb: Clinicaltrials.gov identifier:
`NCT01193504
`
`Vistakon CR1649: A Randomized, Double-Masked, Placebo-Controlled Dose-Response Study of the
`Safety and Efficacy of Two Dosage Strengths of the Bimatoprost Punctal Plug Delivery System (BPPDS)
`Compared to Placebo, Followed by an Open-Label, Single-Dose Bimatoprost 0.03% Ophthalmic
`Solution (LUMIGAN®) Challenge; Sponsored by Vistakon
`
`RPS ADENO DETECTOR IV™ STUDY PROTOCOL; To compare the sensitivity and specificity of the
`RPS Adeno Detector IV™ at detecting the presence of adenovirus to Cell Culture; Sponsored by Rapid
`Pathogen Screening (RPS)
`
`RPS HSV DETECTOR STUDY PROTOCOL; To compare the sensitivity and specificity of the RPS
`HSV Detector at detecting the presence of HSV related keratitis to both cell culture and PCR. Sponsored
`by Rapid Pathogen Screening (RPS)
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`11/09 to 02/10:
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`11/09 to 6/10:
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`11/09 to 02/10:
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`10/09 to 02/10:
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`Tecnis Multifocal IOL vs Restor Pilot Study: Sponsored by Abbott Medical Optics
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`10/09 to present
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`Corneal Collagen crosslinking with riboflavin for Keratoconus, Pellucid, RK, and Post-LASIK ectasia;
`Sponsored by CXLUSA; Clinicaltrials.gov identifier: NCT01024322
`
`10/09 to 07/10
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`Measurement of accommodation with the COAS High Definition Wavefront Aberrometer; Sponsored by
`Abbott Medical Optics
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`06/09 to 07/10
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`The PHACO Study (Prospective Health Assessment of Cataract Patients’ Ocular Surface); Multicenter
`Study, funded by Allergan
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`06/09 to 10/09
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`Determine the Presence of Belpharitis in Patients undergoing Cataract Surgery; Multicenter study,
`funded by Inspire.
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`03/09 to 08/09
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`02/09 to 10/09:
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`2/09 to 7/09
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`2/09 to 5/09
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`2/09 to 6/09
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`A Randomized, Multi-Center, Double-Blind, Placebo-Controlled, Parallel-Group Safety and Efficacy
`Study of Azithromcyin Ophthalmic Solution, 1% versus Placebo for Four Weeks in Subjects with
`Blepharitis (protocol # 044-102): study sponsored by Inspire Pharmaceuticals
`
`A three-month, investigator-masked, randomized, multicenter, parallel, clinical trial comparing the
`efficacy of Combigan® (fixed combination of 0.2% brimonidine tartrate and 0.5% timolol maleate
`ophthalmic solution) versus Xalatan® (latanoprost 0.005% ophthalmic solution) in subjects with ocular
`hypertension or open-angle glaucoma. (Study #: GMA-COM-08-008); sponsored by Allergan
`
`A Multi-Center, Parallel-Group, Double-Masked, Randomized, Placebo-Controlled Study of the Effects
`of diquafosol tetrasodium Ophthalmic Solution, 2% in Subjects with Dry Eye Disease and a Central
`Corneal Staining Score of 3 (NEI Scale). (protocol # 03-113): study sponsored by Inspire
`Pharmaceuticals
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`An Open-Label Study To Assess The Efficacy Of A Combination Povidone-Iodine 0,4%
`(w/w)/Dexamethasone 0.1% (w/w) Ophthalmic Suspension In The Treatment Of Acute Adenoviral
`Conjunctivitis; (OOG-AVC-001); sponsored by Foresight Biotherapeutics
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`PPL GLAU 06: A Partially Masked, Phase 2 Study of the Latanoprost Punctal Plug Delivery System (L-
`PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma (sponsored by QLTI)
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`1/09 to 10/09:
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`PPL GLAU 03: An Open-Label, Phase 2 Study of the Latanoprost Punctal Plug Delivery System (L
`PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma (sponsored by QLTI)
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`12/08 to 1/09:
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`11/08 to 7/2010
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`A Multicenter, Randomized, Double-Masked, Vehicle-Controlled Pilot Study of the Efficacy and Safety
`of Cyclosporine A Ophthalmic Solution (ST-603), 0.1% and 0.2%Compared to Vehicle in Subjects With
`Dry Eye Disease; (Protocol # ST-603-010); Sponsored by Sirion
`
`Evaluation of outcomes using the AMO advanced Customvue™ iLasik procedure (Wavescan
`Wavefront® System, Star S4 IR™ Excimer Laser System and Intralase™ FS System); Sponsored by
`AMO-Abbott
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`11/08 to present
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`A Device Evaluation Study to Assess the Physical and Clinical Performance of Prototype Punctal Plug
`Design Iterations (PP Dev 01); Sponsored by QLTI
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`3
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`PAGE 3 OF 36
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`

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`09/08 to 11/08:
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`William B. Trattler, MD
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`Evaluation of the Crystalens HD (Multicenter (5 sites) outcomes (study sponsored by B&L)
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`7/08 to 1/09:
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`Evaluation Of The Rezoom™ Multifocal And Crystalens™ Accommodating Intraocular Lenses (AMO )
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`7/08 to 1/09:
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`Evaluation Of The Rezoom™ Multifocal And Restor Multifocal Intraocular Lenses (AMO)
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`7/08 to 11/08
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`Efficacy and Safety of Xibrom™ (Bromfenac Ophthalmic Solution) 0.09% QD vs. Placebo QD for
`Treatment of Ocular Inflammation and Pain Associated with Cataract Surgery; Clinical Trial Protocol:
`CL-S&E-0415081-P (Ista)
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`6/08 to 11/08:
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`Evaluation Of Artificial Tears (Blink Tears) In Post-Lasik Patients (AMO)
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`4/08 to 8/09:
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`4/08 to 8/09
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`4/08 to 12/08:
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`03/08 to 6/08:
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`12/07 to 11/08
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`Protocol UVX-002: Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in
`Eyes with Progressive Keratoconus
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`Protocol UVX-003: Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in
`Eyes with Corneal Ectasia after Refractive Surgery
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`Wavetec: a multi-center, prospective study of the wavetec vision systems aberrometer performed in
`subjects undergoing cataract surgery
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`A Multi-Center, Open-Label, Randomized Pilot Study of the Safety and Efficacy of AzaSite®
`Ophthalmic Solution, 1% in Combination with Mechanical Therapy versus Mechanical Therapy Alone in
`Subjects with Blepharitis (sponsored by Inspire pharmaceuticals); Protocol Number: 041-105
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`A Multi-Center, Double-Masked, Randomized, Controlled, Parallel-Group, Three-Month Study (Plus
`Three-Month, Masked Extension) to Evaluate the Safety and Efficacy of Twice-Daily Administered
`Cyclosporine Ophthalmic Emulsion 0.05% (RESTASIS®) in Accelerating the Recovery of Corneal
`Sensitivity in Post-LASIK Patients; PROTOCOL NUMBER: 192371-014-00 (Allergan)
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`12/07 to 12/07:
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`SURFACE: Surveillance of Resistance to Formulations of Antimicrobials in Cultures of the Eye
`(Allergan)
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`11/07 to 1/08:
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`11/07 to 1/08:
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`10/07 to 4/08:
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`8/07 to 5/08:
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`8/07 to 4.08:
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`A Multi Center, Double Masked, Randomized Parallel Group Study Evaluating the Safety and Efficacy
`of a New Formulation of Ketorolac Tromethamine 0.45% Ophthalmic Solution Compared with Vehicle
`Administered Preoperatively and Twice-Daily Postoperatively for Two Weeks for the Treatment of
`Anterior Segment Inflammation, Pain, and Inhibition of Surgically Induced Miosis Following Cataract
`Extraction with Posterior Chamber Intraocular Lens (IOL) Implantation; Protocol #:191578-006
`(Allergan); enrollment complete
`
`Efficacy and Safety of Bromfenac Ophthalmic Solution 0.18% QD vs. Xibrom™ (BromfenacOphthalmic
`Solution) 0.09% QD for Treatment of Ocular Inflammation, Pain, and Photophobia Associated with
`Cataract Surgery; Enrollment Complete
`
`A Multi-Center, Double-Masked, Randomized, Two-Arm, Parallel-Group Study to Compare the
`Efficacy, Safety and Acceptability of Optive™ Unit-Dose Eye Drops with Refresh Plus® Unit-Dose
`Lubricant Eye Drops for Three Months in Subjects following LASIK Refractive Surgery Status:
`PROTOCOL NUMBER: AG9818-001-00 (Allergan)
`
`A 6 Day, Phase 3, Multicenter, Randomized, Double-Masked, Parallel Study to Compare the Safety and
`Efficacy of Gatifloxacin 0.5% Ophthalmic Solution BID with that of Vehicle in the Treatment of Acute
`Bacterial Conjunctivitis; PROTOCOL #: 198782-004-00 (Allergan)
`
`A Phase 3 Double-Masked, Randomized Study of the Safety and Effectiveness of DYME (Brilliant Blue)
`as an Agent for Selective Staining of the Anterior Capsule during Cataract Surgery; Protocol AQNA-
`DY001: (Aqumen Biopharmaceuticals N.A., Inc.)
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`8/07 to 4/08:
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`“A Multicenter, Masked Evaluation of Ocular Surface Tolerability Associated with Bimatoprost 0.03%,
`Travoprost 0.004% (BAK free) or Latanoprost 0.005% Therapy in pts with Glaucoma or OHTN”
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`7/07 to 9/08:
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`6/07 to 11/07:
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`Phase 3 study: An Open-Label, Safety Evaluation of Cyclosporine A Ophthalmic Solution, 0.1% (ST-
`603) Administered Twice Daily for 12 Months to Subjects With Dry Eye Syndrome (ST-603-006)
`
`Phase 3 Study of the Efficacy and Safety of Cyclosporine Ophthalmic Solution, 0.1% (ST-603)
`Compared to Vehicle in Subjects With Moderate to Severe Dry Eye Syndrome( ST-603-005)
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`4
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`PAGE 4 OF 36
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`

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`6/07 to 4/08:
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`William B. Trattler, MD
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`XPF2 Study: Bromfenac BID Plus Prednisolone Acetate BID versus Bromfenac BID Plus Prednisolone
`QID for the Prevention of Cystoid Macular Edema and Retinal Thickening (Principle Investigator)
`Carlos; Educational Grant provided by Ista Pharmaceuticals)
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`3/07 to 11/07:
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`LenstecTM Softec HDTM Posterior Chamber IOL Clinical Study (Phase 3 study); enrollment complete
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`3/07 to 8/07:
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`Phase 3 Multicenter, Randomized, Double-Masked, Placebo-Controlled Study of Difluprednate in the
`Treatment of Inflammation Following Ocular Surgery (Sirion Therapeutics study # ST-601A-002a)
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`11/06 to 1/08:
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`I-Stent Trabecular Bypass Micro Stent in Combination with Cataract Surgery in Subjects with Open-
`Angle Glaucoma, GC-003, Glaukos Corporation (Phase 3 study): Enrollment Complete
`
`10/06 to 1/08:
`
`Efficacy of Topical Cyclosporine Ophthalmic Emulsion for the Prevention and Treatment of Dry Eye
`Symptoms Following LASIK or Photorefractive Keratectomy: Enrollment Complete
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`10/06 to 3/07:
`
`VISTAKON® (senofilcon A) Contact Lens Material, A Retrospective Bandage Lens Usage; Review of
`the Acuvue Oasys as a Bandage Contact Lens. (Vistakon study CR-1550)
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`11/06 to 10/07:
`
`LenstecTM TetraFlexTM Accommodating Posterior Chamber IOL Clinical Investigation (IDE
`G050048); enrollment complete
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`1//06 to 04/07:
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`Evaluation of the IOP-Lowering Effect & Tolerability of Bimatoprost 0.03% (Lumigan®) Compared
`with Travoprost 0.004% (Travatan®) in Patients with Glaucoma or OHTN (Allergan MA-LUM01 study)
`
`9/06 to 12/06:
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`8/06 to 9/08:
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`7/06-12/06:
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`7/06-11/06
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`6/06-11/06
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`6/06-11/06
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`5/06-4/07
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`5/06-12/06
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`5/06-4/07
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`2/06-7/06
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`1/06-4/06
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`11/05-3/06
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`10/5 –3/06
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`5/05-6/05
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`A Randomized Evaluation of Two Surgical Kits: Gatifloxacin, Ketorolac LS, and Pred Forte Compared
`with Moxifloxacin, Nepafenac, and EconoPred in Patients Undergoing Cataract Surgery. Complete
`
`A Multicenter Study on a Rapid screening tests for detection of HSV in tears; Rapid Pathogens
`Screening, Inc
`
`A Randomized, Double-Masked Safety and Efficacy Study of FID #109980 Compared to FID #110656
`in the Treatment of Dry Eye; Phase 3 Dry eye study sponsored by Alcon.
`
`Comparison of Topical Xibrom™ vs Acular LS for the Control of Pain, Photophobia, and Discomfort
`Following PRK; Investigator initiated study, funded by Ista pharmaceuticals
`
`Efficacy and Safety of Topical Bromfenac Ophthalmic Solution 0.18% vs. Placebo for Treatment of
`Ocular Inflammation & Pain and following Cataract Surgery ISTA-BR-CS02 Protocol; Phase 3 study;
`Ista pharmaceuticals; Study completed
`
`A multi-center, randomized, double-masked, parallel clinical trial to evaluate the clinical and microbial
`efficacy of 0.6% ISV-403 compared to Vigamox in the treatment of bacterial conjunctivitis. Phase 3
`study; Bausch & Lomb
`
`A Multicenter Evaluation of Methods to Reduce Hyperemia Associated with Bimatoprost Therapy for
`Glaucoma or Ocular Hypertension; (Educational Grant provided by Allergan)
`
`Comparison of Bimatoprost 0.03% Monotherapy vs. Dual Therapy with Travoprost 0.004% and Timolol
`0.5% in Patients with Glaucoma. (Educational Grant provided by Allergan)
`
`Brimonidine Purite 0.15% versus Dorzolamide 2% Used as Adjunctive Therapy to Latanoprost
`(Educational Grant provided by Allergan)
`
`Comparison of Pred Forte to Acular & Pred Forte for post cataract surgery inflammation (Allergan);
`
`Double-masked study of Acular LS vs Nevanac for pain control following PRK (Educational Grant
`provided by Allergan);
`
`Double-masked study of Acular LS vs Nevanac for pain control following flapless epi-LASIK
`(Educational Grant provided by Allergan);
`
`Double-masked comparison of Restasis vs Refresh for Patients with Contact Lens Intolerance
`(Educational Grant provided by Allergan);
`
`Comparison of Soothe vs Genteal in Patients with Dry Eye due to Computer Vision Syndrome;
`(Educational Grant provided by Alimera Sciences)
`
`5
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`PAGE 5 OF 36
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`

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`4/04 – 8/05
`
`William B. Trattler, MD
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`Clinical Investigator for Alcon Pharmaceuticals in their Phase 3 trial on Topical Rimexolone for dry eye
`
`4/04 – 9/04
`
`Clinical Investigator for Inspire Pharmaceuticals in their Phase 3 trial on Diquafosol (for dry eye)
`
`1/04 – 5/04
`
`Comparison of the Speed of Epithelial Healing following LASEK (Educational Grant provided by
`Alcon)
`
`Clinical investigator for Aqueous Pharma LLC Performed clinical study with TeargardTM for patients
`with evaporative dry eye
`
`Clinical Investigator of the Medennium/Ciba Vision Phakic Refractive Lens (PRL) Phase 3 Investigation
`of Safety and Efficacy for Myopia
`
`Summer Research Fellow in Ocular Immunology
`
`
`
`Mentors:
`
`Scott Cousins, M.D., Assistant Professor, Bascom Palmer Eye Institute
`
`J. Wayne Streilein, M.D., Professor and Chairman, Department of Microbiology &
`
` Immunology, University of Miami School of Medicine
`
`Member of Shark Research Team: Participated in research studying shark growth in Bimini, Bahamas,
`and the diet of young lemon sharks near Little Torch Key (in the Florida Keys)
`
`
`
`Mentor:
`
`
`
`Samuel H. Gruber, Ph.D., School of Marine Science, University of Miami
`
`Summer Research Fellow in Ophthalmology
`
`
`
`Mentor:
`
`Duco I. Hamasaki, Ph.D., Professor, Bascom Palmer Eye Institute
`
`
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`3/02-7/02
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`11/01-2/05
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`6/89-9/89
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`6/87-9/87
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`6/85-9/85
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`PUBLICATIONS
`
`Peer-Reviewed Journal Articles indexed in PubMed
`
`
`
`1. Trattler W. December consultation #5.; J Cataract Refract Surg. 2013 Dec;39(12):1935-6. doi:
`10.1016/j.jcrs.2013.10.011.
`
`2. Moshirfar M, Simpson RG, Dave SB, Christiansen SM, Edmonds JN, Culbertson WW, Pascucci SE,
`Sher NA, Cano DB, Trattler WB. Sources of medical error in refractive surgery. J Refract Surg. 2013
`May;29(5):303-10. doi: 10.3928/1081597X-20130415-01.
`
`3. Farjo AA, Sugar A, Schallhorn SC, Majmudar PA, Tanzer DJ, Trattler WB, Cason JB, Donaldson KE,
`Kymionis GD. Femtosecond lasers for LASIK flap creation: a report by the American Academy of
`Ophthalmology. Ophthalmology. 2013 Mar;120(3):e5-e20. doi: 10.1016/j.ophtha.2012.08.013. Epub
`2012 Nov 20.
`
`4. Brown DC, Gills JP 3rd, Trattler WB, Newsom TH, Weinstock RJ, Sanders DR. Prospective multicenter
`trial assessing effectiveness, refractive predictability and safety of a new aberration free, bi-aspheric
`intraocular lens. Cont Lens Anterior Eye. 2011 Aug;34(4):188-92. doi: 10.1016/j.clae.2011.04.003.
`Epub 2011 May 25.
`
`5. Sher NA, Golben MP, Bond W, Trattler WB. A retrospective review of photorefractive keratectomy to
`enhance earlier radial keratotomy. Int Ophthalmol Clin. 2011 Spring;51(2):39-49.
`
`6. Donnenfeld ED, Nichamin LD, Hardten DR, Raizman MB, Trattler W, Rajpal RK, Alpern LM, Felix C,
`Bradford RR, Villanueva L, Hollander DA, Schiffman RM. Twice-Daily, Preservative-Free Ketorolac
`0.45% for Treatment of Inflammation and Pain After Cataract Surgery. Am J Ophthalmol. 2010 Dec 8.
`[Epub ahead of print]
`
`7. Olson R, Donnenfeld E, Bucci F, Price F, Raizman M, Solomon K,, Devgan U, Trattler W, Dell S,
`Wallace B, Callegan M, Brown H, McDonnell P, Conway T, Schiffman R, Hollander D; Methicillin
`resistance of Staphylococcus species among health care and nonhealth care workers undergoing cataract
`surgery; Clinical Ophthalmology; December 2010.
`
`6
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`PAGE 6 OF 36
`
`

`
`William B. Trattler, MD
`
`8. Schechter BA, Trattler W.; Efficacy and safety of bromfenac for the treatment of corneal ulcer pain. Adv
`Ther. 2010 Sep 13
`
`9. Whitson J, Trattler W, Matossian C, Williams J, Hollander D; Ocular Surface Tolerability of
`Prostaglandin Analogs in Patients with Glaucoma or Ocular Hypertension; Journal of Ocular
`Pharmacology and Therapeutics. June 2010, 26(3): 287-292.
`
`10. Goldman DA, Trattler WB. Cataract surgery and diabetic retinopathy. Ophthalmology. 2010
`Apr;117(4):850; author reply 850
`
`11. Binder PS, Trattler WB. Evaluation of a risk factor scoring system for corneal ectasia after LASIK in
`eyes with normal topography. J Refract Surg. 2010 Apr;26(4):241-50.
`
`12. Trattler W.; Ocular Surface Disease and Osmoprotection in Refractive Surgery Patients; Highlights of
`Ophthalmology. Vol. 38, No 2; 2010
`
`13. Huang D, Schallhorn SC, Sugar A, Farjo AA, Majmudar PA, Trattler WB, Tanzer DJ.; Phakic
`intraocular lens implantation for the correction of myopia: a report by the American Academy of
`Ophthalmology. Ophthalmology. 2009 Nov;116(11):2244-58. Review.
`
`14. AJ. S. Pelletier · K. Stewart · W. Trattler · D. C. Ritterband · S. Braverman · C. M. Samson · B. Liang ·
`J. A. Capriotti; Combination Povidone-Iodine 0.4%/Dexamethasone 0.1% Ophthalmic Suspension in the
`Treatment of Adenoviral Conjunctivitis; Adv Ther (2009) 26(8):. DOI 10.1007/s12325-009-0062-1
`
`15. Trattler W, Binder PS; Scoring system minimizes key variables. Ophthalmology. 2009 May;116(5):101
`
`16. Neal A. Sher, MD, FACS; Mikhail P. Golben, BS; William Bond, MD; William B. Trattler, MD;
`Shachar Tauber, MD; Terry G. Voirin, DO. Topical Bromfenac 0.09% vs Ketorolac 0.4% for the
`Control of Pain, Photophobia, and Discomfort Following PRK. Journal of Refractive Surgery Vol. 25
`No. 2 February 2009
`
`17. Buznego C, Trattler WB.; Presbyopia-correcting intraocular lenses. Curr Opin Ophthalmol. 2009
`Jan;20(1):13-8.
`
`18. Yuen L, Trattler W, Boxer Wachler BS.; Two cases of Z syndrome with the Crystalens after uneventful
`cataract surgery. J Cataract Refract Surg. 2008 Nov;34(11):1986-9.
`
`19. Wittpenn JR, Silverstein S, Heier J, Kenyon KR, Hunkeler JD, Earl M; Acular LS for Cystoid Macular
`Edema (ACME) Study Group. A randomized, masked comparison of topical ketorolac 0.4% plus
`steroid vs steroid alone in low-risk cataract surgery patients. Am J Ophthalmol. 2008 Oct;146(4):554-
`560.
`
` Collaborators (15): Wittpenn J, Silverstein S, Hunkeler J, Schechter B, Price F, Chu R, Wallace B,
`Trattler W, Dougherty P, Goldberg D, Perry H, Solomon K, Donnenfeld E, Kenyon K, Roberts
`20. Schallhorn SC, Farjo AA, Huang D, Boxer Wachler BS, Trattler WB, Tanzer DJ, Majmudar PA, Sugar
`A; American Academy of Ophthalmology. Wavefront-guided LASIK for the correction of primary
`myopia and astigmatism a report by the American Academy of Ophthalmology. Ophthalmology. 2008
`Jul;115(7):1249-61.
`
`21. Trattler W, Barnes S; Current Trends in Advanced Surface Ablation; Current Opinion of
`Ophthalmology; 2008: 19:330–334
`
`22. Trattler W, Noecker RJ, Earl ML. A multicentre evaluation of the effect of patient education on
`acceptance of hyperaemia associated with bimatoprost therapy for glaucoma or ocular hypertension.
`Adv Ther. 2008; 2008:25:179-189
`
`23. Randleman JB, Trattler WB, Stulting RD. Validation of the Ectasia Risk Score System for preoperative
`laser in situ keratomileusis screening. AJO. 2008 May;145(5):813-8.
`
`24. Krueger RR, Trattler W, Yee R. Introduction to the proceedings of the Sixth International Congress on
`Advanced Surface Ablation & SBK. J Refract Surg. 2008 Jan;24(1):S55-6
`
`25. Caster AI, Trattler W. Corneal ectasia after laser vision correction; Int Ophthalmol Clin. 2008
`Winter;48(1):73-81.
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`William B. Trattler, MD
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`26. Trattler WB, McDonald M; Double-Masked Comparison of Ketorolac Tromethamine 0.4% Versus
`Nepafenac Sodium 0.1% for Postoperative Healing Rates and Pain Control in Eyes Undergoing Surface
`Ablation; Cornea, August 07; 665-669
`
`27. Trattler W, Katsev D, Kerney D; Self-reported compliance with topical cyclosporine emulsion 0.05%
`and onset of the effects of increased tear production as assessed through patient surveys.; Clin
`Ther.2006 Nov;28(11):1848-56
`
`28. Trattler WB, Luchs J, Majmudar P. Elestat (epinastine HCl ophthalmic solution 0.05%) as a therapeutic
`for allergic conjunctivitis. Int Ophthalmol Clin. 2006 Fall;46(4):87-99.
`
`29. Trattler W, Salz JJ. Surface ablation over LASIK flaps. Int Ophthalmol Clin. 2006 Summer;46(3):117-22
`
`30. Salz JJ, Trattler W. Pupil size and corneal laser surgery. Curr Opin Ophthalmol. 2006 Aug; 17(4):373-9.
`
`31. Di Pascuale M, Liu T, Trattler W, Tseng S. Lipid Tear Deficiency in Persistant Dry Eye After Laser in
`situ Keratomileusis and Treatment Results of New Eye-Warming Device; JCRS Sep 05; 32 (9)1741-49
`
`32. Durrie D, Trattler W. A Comparison of Therapeutic Regimens Containing Moxifloxacin 0.5%
`Ophthalmic Solution and Gatifloxacin 0.3% Ophthalmic Solution for Surgical Prophylaxis in Patients
`Undergoing LASIK or LASEK. Journal of Ocular Pharmacology & Therapeutics. 21(3)2005:236-41
`
`33. Trattler W, Whitsett J, Simone, P, Negative Dysphotopsia After Intraocular Lens Implantation
`Irrespective of Design & Material, Journal of Cataract and Refractive Surgery. 31 (April 2005): 841-844
`
`34. Salz JJ, Boxer Wachler BS, Holladay JT, Trattler W. Night vision complaints after LASIK
`Ophthalmology. 2004 Aug;111(8):1620-1; Comment on: Ophthalmology. 2004 Jan;111(1):3-10.
`
`35. Ta CN, Shine WE, McCulley JP, Pandya A, Trattler W, Norbury JW. Effects of Minocycline on the
`Ocular Flora of Patients with Acne rosacea or Seborrheic Blepharitis. Cornea. 2003 Aug;22(6):545-8
`
`36. Cousins S.W., Trattler W.B., and Streilein J.W. Immune Privilege and Suppression of Immunogenic
`Inflammation in the Anterior Chamber of the Eye. Current Eye Research. 10 (1991): 287-297.
`
`37. Hamasaki D.I., Trattler W.B., and Hajek A.S. Light ON Depresses and LightOFF Enhances the Release
`of Dopamine from the Cat's Retina. Neuroscience Letters. 68 (1986): 112-116.
`
`
`
`
`Abstracts/Posters at National Meetings
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`1. Poster #5352 - Evaluation of epi-on corneal collagen cross-linking (CXL) at 6 months and 1 year follow-
`up in patients diagnosed with keratoconus and post-LASIK ectasia; European Society of Cataract and
`Refractive Surgery (ESCRS); September 2014
`
`2. Poster # A0248; Loh J, Trattler W, Rubinfeld R, Perez; Evaluation of Transepithelial Corneal Collagen
`Cross-Linking (CXL) at 6 months and 1 year Follow Up in Patients with Different Proprietary
`Transepithelial Riboflavin Solutions; Presented at The Association for Research in Vision and
`Ophthalmology Annual Meeting; May 5th 2014; Orlando, FL
`
`3. Poster # C0246: Abou-Jaoude M, Trattler W, Buznego C, Hovanesian J, Henderson B; Randomized,
`Masked Comparison of Bromfenac and Besifloxacin BID With Either Prednisolone BID or Loteprednol
`0.5% BID for Prevention of Retinal Thickening and CME Following Phacoemulsification; Presented at
`The Association for Research in Vision and Opthalmology Annual Meeting; May 5th 2014; Orlando, FL
`
`4. Poster #B0262; Frank B, Trattler W, McCabe S, Correa R, Loh J, Buznego C; The Incidence of
`Topographic Abnormalities in Patients Scheduled for Cataract Surgery; Presented at The Association for
`Research in Vision and Opthalmology Annual Meeting; May 5th 2014; Orlando, FL
`
`5. Poster #7036; Trattler W, Frank B, McCabe S, Loh J, Buznego C; Retrospective Review of Incidence of
`Abnormal Corneal Topography in Patients Scheduled for Cataract Surgery; Presented at the American
`Society of Cataract and Refractive Surgery Annual Meeting; April 25th 2014; Boston, MA
`
`6. Rubinfeld R, Trattler W, Forstot L, Martin F, Kaiser C, Talamo J, Hatch K, Correa R, Retrospective
`evaluation of epithelial –on cross-linking (CXL), Poster Accepted for the American Academy of
`Ophthalmology Annual Meeting, November 11, 2012, Chicago, IL
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`William B. Trattler, MD
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`7. Trattler W, Buznego C, Luchs J, Adi M, Rubinfeld M, Berdy G, Perez G, Abou-Jaude M, Retrospective
`evaluation of patients with a strong response to epithelial –on corneal collagen cross-linking (CXL),
`Poster Accepted for the American Academy of Ophthalmology Annual Meeting, November 11, 2012,
`Chicago, IL
`
`8. Trattler W, Lacayo G, Perez G, Feldman S, Majmudar P, Malahotra R, Comparison of epithelial-on
`cross-linking for the treatment of mild, moderate, and severe keratoconus, Poster Accepted for the
`American Academy of Ophthalmology Annual Meeting, November 11, 2012, Chicago, IL
`
`9. Rubinfeld R, Trattler W, Forstot L, Martin F, Kaiser C, Talamo J, Hatch K, Correa R, Retrospective
`evaluation of epithelial –on cross-linking (CXL), ePoster Accepted for the ISRS subspecialty day
`meeting, AAO, November 9-10, 2012, Chicago, IL
`
`10. Trattler W, Lacayo G, Perez G, Feldman S, Majmudar P, Malahotra R, Comparison of epithelial-on
`cross-linking for the treatment of mild, moderate, and severe keratoconus, ePoster Accepted for the ISRS
`Subspecialty day Meeting, AAO, November 9-10, 2012, Chicago, IL
`
`11. Trattler W, Buznego C, Luchs J, Adi M, Rubinfeld M, Berdy G, Perez G, Retrospective evaluation of
`patients with a strong response to epithelial –on corneal collagen cross-linking (CXL), ePoster Accepted
`for the ISRS subspecialty day meeting, AAO, November 9-10, 2012, Chicago, IL
`
`12. Poster 363: Rubinfeld R, Trattler, W, Majmudar, P, Epstein, R, Adi, M, Wallace, D, McCall, T, Martin,
`N, Letko, E, Intili, A, Perez, G, Multicenter evaluation of trans-epithelial versus epithelial-off corneal
`collagen crosslinking (CXL) for keratoconus and post-LASIK ectasia; American Academy of
`Ophthalmology Annual Meeting; Orlando, Florida; October 24-25, 2011
`
`13. E-Poster 101455: Trattler W, Khell J, Perez G, Retrospective evaluation of tecnis multifocal (ZMA00 or
`ZMB00) intraocular lenses following phacoemulsifaction in optimized patients; The International
`Society of Refractive Surgery (ISRS) Annual Meeting; Orlando, Florida; October 21-22, 2011
`
`14. E-Poster 101324: Trattler W, Rubinfeld R, Majmudar P, Letko E, Forstot L, Perez G, Berdy G, Schwartz
`J, Hatch K, Kaiser C, Baffna S, Wiley W, Evaluation of epithelial-on corneal collagen crosslinking;
`ISRS Annual Meeting; Orlando, Florida; October 21-22, 2011
`
`15. E-Poster 101325: Majmudar P, Rubinfeld R, McCall T, Epstein R, Bowman B, Luchs J, Perez G,
`Malahotra R, Trattler W, Evaluation of epithelial-on corneal collagen crosslinking in patients ages 35
`or older; ISRS Annual Meeting; Orlando, Florida; October 21-22, 2011
`
`16. E-Poster101414: Rubinfeld R, Adi M, Intili A, Morgenstern A, Gelender H, Beebe W, Koreshi A,
`Trattler W, Perez G, Comparative evaluation of epithelial-on vs epithelial-off corneal collagen
`crosslinking (CXL); ISRS; Orlando, Florida; October 21-22, 2011
`
`17. Poster: Trattler W, Buznego C, Perez G, Kshetrapal A, Katzen L, Khell J, Retrospective evaluation of
`tecnis multifocal (ZMA00 or ZMB00) and ReSTOR (SN60D1) intraocular lenses following
`phacoemulsifaction; Poster accepted for XXIX Congress of the European Society of Cataract and
`Refractive Surgeons (ESCRS), September 17-21, 2011, Vienna, Austria
`
`18. Poster: Trattler W, Rubinfeld R, Majmudar P, Malhotra R, Schwartz J, Feldman S, Hatch K, Perez G,
`Forstot L, Wiley B, Multicenter evaluation of trans-epithelial versus epithelial-off corneal collagen cross
`linking (CXL) for keratoconus and post-LASIK ectasia; Poster accepted for ESCRS, September 17-21,
`2011, Vienna, Austria
`
`19. Poster: Luchs J, Buznego C, Trattler W; Asymptomatic or Minimally Symptomatic Blepharitis in
`Patients Having Cataract Surgery; ASCRS; San Diego; March 2011
`
`20. Poster: Kotha A; Singh S; Trattler W; Buznego C; Visual Outcomes of Glaucoma Patients Receiving
`Presbyopia-Correcting IOL; ASCRS; San Diego; March 2011
`
`21. Poster: Singh S, Trattler W, Perez G; Lin D; Crosslinking Followed by Topography-Guided PRK in a
`
`9
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