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`COMPANY PROFILE
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`Page 1 of 18
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`LUPIN V. SENJU
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`Page 1 of 18
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`SENJU EXHIBIT 2196
`LUPIN v. SENJU
`IPR2015-01097
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`President’s Message
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`The characters that comprise Senju's company name in the Japanese language are “Sen" and “Ju”, which
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`literally mean “thousand” and “bringing happiness”, respectively. Senju, bringing much (a thousand)
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`happiness, has an objective to bring a “happiness” to the people associated with us through the
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`development of original pharmaceutical products for the care of the five senses (eyes, ears, nose, throat
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`and skin), which ultimately improves the joy of living.
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`This is our management policy; “Good Company".
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`We strongly believe that Senju should be a trustworthy and essential company by putting ourselves into the
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`other person's shoes and acting under the Action Guideline; “If I were you”.
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`Yukoh Yoshida
`President & CEO
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`President'sMessage
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`Page 2 of 18
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`Management Policy
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`Good Company
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`At Senju Pharmaceutical, our mission is to pursue happiness
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`for every person associated with the company.
`“Being a good company“ is our management policy.
`As a company that aims to be reliable, necessary, and valuable to society, we are
`committed to pursuing happiness for all people associated with the company, rather than
`simply becoming a “Big Company” that pursues only greater growth and increased sales.
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`Action Guideline
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`If I were you
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`“If I were you”
`Considering others’ viewpoints is the starting point for all of our business activities.
`We should not do to others what we would not like to be done to us.
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`To treat others in a way that would make us happy if we were treated that way, we
`need to think about and do things from others’ points of view at all times.
`These are the action guidelines that Senju Pharmaceutical employees aim to follow.
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`5 N
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`SENSE
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`SENJU SENSE is a systematic collection of the concepts and values that have
`been carefully handed down over the generations since the founding of our
`company, including our Management Policy “Good Company”. It is a collective
`name for Senju’s values, which are so essential during decision-making and the
`execution of our responsibilities. By ensuring that each and every employee
`shares our SENJU SENSE and works with firm belief in the pursuit of happiness
`for all people associated with the company, we aim to come up with a variety of
`innovative new ideas, thereby ensuring that Senju remains a “Good Company”.
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`Page 3 of 18
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`Ethical Products
`for Medical Professionals
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`As a manufacturer of ophthalmological drugs, Senju Pharmaceutical
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`has entered the promising fields on the front lines of medicine.
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`In addition to creating new medicines, particularly
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`ophthalmic solutions in the field of eye medicine, Senju
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`Pharmaceutical offers a broad range of generic products
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`and we steadily implement measures to respond to
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`changes in the market environment. What's more, we
`also work hard to develop and promote what’s referred to
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`as “orphan drugs", which treat rare diseases suffered by
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`extremely small numbers of patients.
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`Senju Pharmaceutical will take on new challenges every
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`day with the aim of “maintaining and improving vision” for
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`as many patients as possible by increasing the added
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`value of our products by strengthening the information
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`gathering and communication capabilities we have built
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`up over many years in the field of ophthalmology and by
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`accurately identifying treatment needs in the medical
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`workplace as well as by enhancing our marketing, sales
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`and logistics functions for promoting activities to
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`encourage the rapid popularization of our products.
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`Page 4 of 18
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`M M S (Medical Management Supporter)
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`For Human, for Medical, for Tomorrow.
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`Senju Pharmaceutical has developed an MMS
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`(Medial Management Supporter) business to provide
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`various types of support for the operation of eye
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`clinics with the aim of contributing to healthcare in
`local communities.
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`Strong clinic management is essential to providing
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`high-quality health-care.
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`Through MMS we provide support to the many
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`management challenges faced by ophthalmologists,
`including the handling of reforms to various systems,
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`labor management, the fostering of human resources,
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`the handling of tax issues, building partnerships with
`otherfacilities, and improving patient satisfaction.
`What's more, in order to provide ever-changing
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`management information service website.
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`Architectural models
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`Over the Counter (OTC) Products
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`The Mytear brand was developed from our research into tears.
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`Tears are invaluable to our eyes and they have even
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`is an over-the-counter product containing
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`been described as “heaven’s eye medicine".
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`pranoprofen, a nonsteroidal anti-inflammatory drug
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`Thanks to our ongoing efforts in tear research, in
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`that has been recognized as an effective and safe
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`1965 Senju Pharmaceutical launched Japan's first
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`prescription product.
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`ever tear-type eye medicine, the artificial tear
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`Mytear.
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`Fifteen years later in 1980 we launched Mytear CL
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`as a contact lens use eye medicine, the first in
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`Japan that could be applied while still wearing soft
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`contact lenses. We have continued to develop eye
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`medicine under the Mytear brand in response to
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`changing times and changing user needs.
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`In recent years, we have utilized our product
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`development capabilities as a manufacturer of
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`prescription eye medicine and our many years of
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`marketing experience to launch unique and high
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`quality products, including Mytear EYETECT, which
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`Page 6 of 18
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`Overseas Activities
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`When it comes to eye health and the development of
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`pharmaceutical products, there are no national borders.
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`Senju Pharmaceutical promotes international
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`SCIENCE & TECHNOLOGY (BEIJING) CO., LTD.
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`activities with an eye on the pharmaceutical products
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`and local manufacturing and sales company SENJU
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`of tomorrow, beyond the limits of individual countries
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`WANHE PHARMACEUTICAL (SHENZHEN) CO., LTD.
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`We are actively seeking to expand the scope of our
`activities and have established local offices in Russia
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`and Vietnam.
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`or companies.
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`As we approach the global age, Senju
`Pharmaceutica|’s overseas activities have become
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`more diverse than ever. We have promoted the export
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`of finished products, new product technology and
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`patent derivations, and we are now active in more
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`than 50 countries. In order to build partnerships and
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`introduce the latest technologies and information as
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`quickly as possible, it is necessary to remain
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`unconstrained by regional location, industry or scale.
`In the United States, we have established a
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`subsidiary SENJU USA, INC. with the aim of
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`promoting research and development in United
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`States pharmaceutical products. In China, we have
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`established subsidiary SENJU PHARMACEUTICAL
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`Page 7 of 18
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`Research and Development
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`We are using our cutting edge technology and unique research
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`system to pursue the limitless possibilities of people and science.
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`“All things in nature have a reason for being.
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`research into the creation of treatments by using cutting
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`Today’s common sense is not common sense tomorrow.”
`This is the motto of our researchers.
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`edge technology to identify the molecules that cause eye
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`diseases. At our Kobe Creative Center, we promote
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`Senju Pharmaceutical pursues research and development
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`research that will lead directly to product development,
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`through flexible thinking without being constrained by
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`existing limits or stereotypes through our unique research
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`including accumulating the data needed for the approval of
`pharmaceutical products. All of our centers work in close
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`system, which includes international joint research projects
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`cooperation on this research. Our eyes are fixed firmly on
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`and collaborative research with industry and academia.
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`the future. Our goal and aspiration is to develop the
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`At the Senju Laboratory of Ocular Science and our Oregon
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`pharmaceutical products that are truly needed by society,
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`Laboratory in the United States, we carry out basic
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`safely and as quickly as possible.
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`I Kobe Creative Center
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`I Senju Laboratory of Ocular Science
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`I Oregon Laboratory, United States
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`Page 8 of 18
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`Production
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`Bringing you high quality pharmaceutical products from
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`factories that meet PIC/S GMP standards
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`When manufacturing pharmaceutical products, it is
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`standards at an early stage in anticipation of revisions to
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`essential to comply with the GMP (Good Manufacturing
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`GMP standards. Moreover, we have built a system that
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`Practice) standard for the manufacture of pharmaceutical
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`allows us to implement ongoing improvements to reduce
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`products and quasi drugs, from delivery of raw materials
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`our impact on the environment.
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`through to shipment of the finished product.
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`What’s more, because eye medicine is a sterile product,
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`We will continue to deliver a steady supply of high quality
`pharmaceutical products to Japan and the world from
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`there is a need for sterile manufacturing facilities that
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`factories that combine state-of-the-art manufacturing
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`guarantee a high level of sterility, and a need for the
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`facilities with a state-of-the-art manufacturing environment.
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`installation of testing equipment and quality control.
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`Senju Pharmaceutical works to comply with PIC/S-GMP
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`PIC/S: The Pharmaceutical Inspection Convention and
`Pharmaceutical Inspection Co-operation Scheme
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`I Manufacturing Plant Karatsu
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`I Manufacturing Plant Fukusaki
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`Status of |SO14001 Certification Acquisition : Plant Fukusaki in December 2007/ Plant Karatsu in December 2014
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`Page 9 of 18
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`Animal Health
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`Using the pharmaceutical technologies developed for
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`humans to develop health products for companion animals
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`People are not the only living things to use sense
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`organs such as the eyes and ears to collect
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`abundant information for use in their everyday lives.
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`Sense organs are also an essential part of the daily
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`lives of the pets who live side by side with humans.
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`In recent years, improved living standards and
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`medical advances have increased the length of time
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`that pets and humans can live side by side, leading
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`to increased risk from ageing associated lifestyle
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`diseases and increased importance of the sense
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`organs in pets’ daily lives. Senju Pharmaceutical has
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`continued to utilize the pharmaceutical development
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`technologies we have accumulated over many years
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`of developing human sensory organ pharmaceutical
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`products in the development and promotion of animal
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`pharmaceutical products and other animal products,
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`helping our pets to live long and happy lives.
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`Alleviation ar the Five Senses I
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`Page 11 of 18
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`Alleviation for the Five Senses I
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`SEN
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`Senju Pharmaceutical Co., Ltd.
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`2-5-8, Hirano-machi, Chuo-ku, Osaka
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`TEL : O6-6201-2512 (main switchboard)
`FAX :06-6226-0406
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`URL : http://www.senju.co.jp
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`e 12 of 18
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`Page 12 of 18
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`Milestones in Our History
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`Capital increased to 1,415,500,000 yen.
`NSAID Ophthalmic Solution, "NIFLAN", launched.
`Los Angeles Office opened in USA.
`Kobe Creative Center completed.
`Yokohama Branch opened.
`Kobe Branch opened.
`Chiba Branch and Saitama Branch opened.
`NSAID Ophthalmic Solution, "BRONUCK", launched.
`A laboratory completed in Oregon, USA.
`The European Office opened.
`Beijing Office opened in China.
`Senju USA, Inc. established.
`Senju Laboratory of Ocular Science, Kobe Laboratory
`completed.
`Yukoh Yoshida becomes the President of the Company.
`Senju Medical Consulting (Shanghai) Co., Ltd. established in
`Shanghai, China.
`Osaka Logistical Warehouse opened.
`Manufacturing Plant Karatsu built at 4228-1 Ishishi,
`Karatsu-shi, Saga.
`Ophthalmic Solution for Glaucoma Ocular Hypertension,
`“LUMlGAN", launched.
`Senju Pharmaceutical Science & Technology (Beijing) Co.,
`Ltd. established.
`Hanoi Office opened in Hanoi, Vietnam.
`Ophthalmic Solution for Glaucoma Ocular Hypertension,
`“A|PHAGAN", launched.
`Moscow Office opened in Moscow, Russia.
`Saitama Office opened.
`Chiba Office opened.
`Shizuoka Satellite Office opened.
`Senju Wanhe Pharmaceutical Shenzhen Corp. established in
`Shenzhen, China as a joint company.
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`The Company founded at 12-Ishigatsuji-cho, Tennoji-ku,
`Osaka. Start-up capital of 195,000 yen. President, Hiroshi
`Tsuzuki.
`Injection Product for Neutropenia, "PANILTIN", launched.
`Reishin Tanimura becomes the President of the Company.
`Company head office relocated to 2-42 Hirano-machi,
`Higashi-ku, Osaka.
`Manufacturing plant relocated to 482 lwazono-cho, Ashiya City.
`Agreement concluded with Takeda Pharmaceutical Company
`Limited for the sole distribution of Senju Products.
`Capita increased to 780,000 yen.
`Masao Yoshida becomes the President of the Company.
`Capita increased to 3,000,000 yen.
`Tokyo Branch opened.
`Ophthalmic Solution for Cataracts, "CATALIN", launched.
`Capita increased to 6,000,000 yen.
`Implementation of the City Planning Act meant the company
`reloca ed the Ashiya Plant to a newly-built plant at 416
`lwazono-cho.
`Fukuoka Branch opened.
`Capita increased to 9,000,000 yen.
`Capita increased to 13,500,000 yen.
`Itami Plant newly built for the manufacture of ingredients at 1-1
`Oshika-Sakuragaoka, Itami City.
`Capita increased to 18,000,000 yen.
`Laboratory and attached facilities newly built at the Ashiya
`Plant.
`Capita increased to 30,000,000 yen.
`Artificial Tear Ophthalmic Solutions, “MYTEAR", launched.
`Company head office relocated to 1-83 Doshin-cho, Kita-ku,
`Osaka.
`Nagoya Branch opened.
`Capital increased to 75,000,000 yen.
`Sendai Branch opened.
`Sapporo Branch opened.
`Laboratory completed in the Itami Plant.
`Company head office and Osaka Branch relocated to 3-28
`Hirano-machi, Higashi-ku, Osaka (Amakasu Building).
`Hiroshima Branch opened.
`Capital increased to 150,000,000 yen.
`Manufacturing Plant Fukusaki built at 767-7 Kazukanonishi,
`Saiji, Fukusaki-cho, Kanzaki-gun, Hyogo.
`Capital increased to 225,000,000 yen.
`Shoji Yoshida becomes the President of the Company.
`Company head office relocated to 3-6-1 Hirano-machi,
`Higashi-ku, Osaka (7'“ Floor of Hirano-machi Century Building).
`Ophthalmic Solution for use on contact lens, "MYTEAR CL",
`launched.
`Capital increased to 450,000,000 yen.
`A biological laboratory completed in the Itami Research
`Laboratory.
`Capital increased to 1,050,000,000 yen.
`Utsunomiya Branch, Matsumoto Branch, and Takamatsu
`Branch opened.
`Kyoto Branch opened.
`lntraocular irrigating Solution, "OPEGUARD MA", launched.
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`September
`November
`April
`July
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`Company Profile
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`Trade Name
`Principal Office
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`Senju Pharmaceutical Co., Ltd.
`2-5-8, Hirano-machi, Chuo-ku, Osaka, 541-0046, Japan
`TEL: +81-6-6201-2512
`FAX: +81 -6-6226-0406
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`Date of Incorporation April, 1947
`Representative
`Yukoh Yoshida
`Capital
`1.4 billion yen
`Employees
`861 (as of March 2015)
`Sales
`35 billion yen (as of March 2015)
`Accounting Period
`March
`Business Content
`(1) Pharmaceutical business: manufacture and sale of prescription eye, ear,
`nose and throat medicines, contact lens solutions and animal medicines
`(2) Other business: manufacture and sale of raw materials for cosmetics
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`I Matters related to officers
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`Member of the Board of Directors
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`Executive Officer
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`Shoji Yoshida
`Yukoh Yoshida
`Shuhei Yoshida
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`Chairman of the Board
`President & CEO
`Executive Vice President & COO
`Head of Corporate Management Division and Business Strategy Division
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`Takeshi Sugisawa Head of Business Development Division
`Hidemi Shimoji
`Head of Research and Development Division
`Mikio Ogawa
`Head of Overseas Business Division
`Tomio Maenaka
`Head of Production Division
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`M“S“Y°Sl“ Azuma
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`Takashi Masuda
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`Akemi Yamasaki
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`Ma"39‘“9 EX°““Ve °"i°°'
`Head of Laboratory, Senju Laboratory of Ocular Science
`Managing Excutive Officer
`Head of Pharmaceutical Marketing Division
`Corporate Auditor
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`Michinari Wada
`Takahiro Ogawa
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`Head of Reliability Assurance Division
`President of SENJU USA (secondment)
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`I Trends in Sales and Current Profits
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`Sales (unit: ¥ billion)
`35.0
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`30.0
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`25.0
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`Current Profits (unit: ¥ billion)
`9_o
`8.0
`7.0
`6.0
`5.0
`4.0
`3.0
`2.0
`1.0
`0
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`2011
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`2012
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`2013
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`2014
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`Sales(unit: ¥ billion) :0: Current Profits (unit: ¥ billion)
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`Sales
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`Current profits
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`.
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`2011
`25.1
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`4.4
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`2012
`28.6
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`2.6
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`2013
`33.0
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`5.1
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`Unit: Billion yen
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`Page 14 of 18
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`iCCS (Overseas)
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`I Laboratories and Offices
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`OSENJU LABORATORY OF OCULAR SCIENCES (SLOS)
`OTRADI Bioscience Incubator, 4640 SW Macadam Ave., Suite 2000, Portland, OR 97239, U.S.A.
`Te I: +1-503-748-5202
`Fax: +1-503-748-5204
`.$ENJU PHARMACEUTICAL 00., LTD. BEIJING OFFICE
`Unit 3602, Fortune Plaza Office Tower A, No.7 Dongsanhuan Zhonglu, Chaoyang District, Beijing, 100020 P.R.C
`Tel: +86-10-6533-0200
`Fax: +86-10-6536-1329
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`OSENJU PHARMACEUTICAL co., LTD. Hanoi Representative Office
`Room 1314, Level 13, Ha Noi Towers, 49 Hai Ba Trung, Hoan Kiem District, Ha Noi, Vietnam
`Tel: +84-4-3934-3890
`Fax: +84-4-3934-3966
`OMoscow Representative Office of Senju Pharmaceutical Co., Ltd.
`Office No.105, 1st floor, str. 6, dom 1A, Tretiy Nizhnelikhoborskiy proyezd, Moscow 125371, Russian Federation
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`Isubsidiaries
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`OSENJU USA, INC.
`21700 Oxnard Street, Suite 1070 Woodland Hills, CA 91367, U.S.A.
`Tel: +1-818-719-7190
`Fax: +1-818-719-7195
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`OSENJU PHARMACEUTICAL SCIENCE & TECHNOLOGY (BEIJING) co., LTD.
`Unit 3602, Fortune Plaza Office Tower A, No.7 Dongsanhuan Zhonglu, Chaoyang District, Beijing, 100020 P.R.C
`T e I: +86-10—6533—020O
`Fax: +86—10-8536-1329
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`OSENJU WANHE PHARMACEUTICAL (SHENZHEN) co., LTD.
`Block B, Wanhe Technology Complex, Hi-tech Park, Guangming District, Shenzhen, Guangdong Province, China
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`Page 15 of 18
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`Offices (Japan)
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`I Head Office
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`Hirano-machi Century Building
`2-5-8, Hirano-machi, Chuo-ku, Osaka, 541-0046
`TEL: +81-6-6201-2512 (main switchboard) FAX: +81-6-6226-0406
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`I Branches and Groups
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`[Northern Japan Branch]
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`Takeda 3aPP°r° BU“di“9»
`13-4, Kitaichijonishi, Chuo-ku, Sapporo-shi, Hokkaido, 060-0001
`TE‘-I +81-11-221-2743
`'5°"°a‘ °"‘°°v T°"°k" ""5" G'°“Pv T°“°"“ 5°°°"“ °'°“P
`Takeda Sendai B'~‘"di"9
`2-13-21, H°"°h°i A°b3'kU» 3e"dai'Shi» 'V“Ya9i- 930-0014
`TEL: +31-22454-2233
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`[Saitama Kitakanto Shinetsu Branch]
`Outsunomiya Office, Kita—Kanto Group
`Ch”° Ut5“”°miYa B“”di”9
`3-1-1 Hi9aShiShUk“9°- UiSU"°miYa-Shh T°°hi9ii 321-0953
`TEL1*31-23-533-525°
`Osaitama Office, Saitama Group, Shinetsu Group
`82 Om“/3 B““di”9
`1-11-3, Sakuragicho, Omiya-ku, Saitama-shi, Saitama, 330-0854
`TE'-5 +81-43-558-234°
`[Karma Branch]
`Qchiba Office, Chiba Group
`Lalaport Mitsui Building
`2-1-1, Hamacho, Funabashi-shi, Chiba, 273-0012
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`[Tokai Branch]
`.Nagoya Office, Tokai First Group, Tokai Second Group
`Nishiki Park Building
`2_4_3! Nishiki’ Naka_ku’ Nagoya_shi’ Aichii 45o_0003
`TEL: +81-52-211-2560
`Oshizuoka Satellite Office, Tokai First Group (Shizuoka base)
`Mitsui Seimei Shizuoka—ekimae Building
`11-7, Kuroganecho, Aoi—ku, Shizuoka—shi, Shizuoka, 420-0851
`TEL: +81—52—211—2560 (Nagoya Office)
`
`maiisai Shikoku Biaiichi
`.Ky°i° office’ Kyoto Group
`Sumitomo Seimei Kyoto Building
`62, Tsukihokocho, Shinmachihigashiiru, Shijodori,
`Shimogyo—ku, Kyoto—shi, Kyoto, 600-8492
`TEL: +81—75—229—6549
`Oosaka Office, Osaka First Group, Osaka Second Group
`Takeda i.iii.ano_machi Buiiding
`2-4-9, Hirano—machi, Chuo-ku, Osaka, 541-0046
`TEL: +81-6-6226-0403
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`K°be Homachi B”"di”9
`121» "°'“a°h'» Ch“°"<“v K°be'5“'» "'V°9°» 65043032
`
`OTokyo Office, Tokyo First Group, Tokyo Second Group, Tokyo Third Group
`MFPR Nihonbashihonciio Buiiding
`3_7_2! Nihonbashihoncim Chuo_ku_ -i—°ky0_ 103_0023
`TEL: +81-3-5643-1950
`.Yokohama Office, Yokohama Group
`Hi9a5h“°t5'-‘K3 West B””di”9
`90-6, Kawakamicho, Totsuka-ku, Yokohama-shi, Kanagawa, 244-0805
`TEL? +81'45'828'1381
`
`.Takama‘5" °ffi°°l 5hik°k" emu”
`Takamatsu Daiichi Seimei Building
`1-3-2, Kotobukicho, Takamatsu-shi, Kagawa, 760-0023
`TEL3 +31'87'822'9492
`[Kyushu Chugoku Branch]
`.Hiroshima Office, Chugoku Group
`Takeda Hiroshima Buiiding
`1-25, Komachi, Naka-ku, Hiroshima-shi, Hiroshima, 730-0041
`TEL: +81-82-248-2023
`
`OFukuoka Office, Kyushu First Group, Kyushu Second Group
`Fukuoka Takeda Building
`9-12, Shimokawabatamachi, Hakata-ku, Fukuoka-shi, Fukuoka, 812-0027
`TEL: +81-92-271-2390
`
`I Manufacturing Plants and Research Laboratories
`
`.Manufacturing Plant Karatsu
`4228-1, lshishi, Karatsu-shi, Saga, 847-0832
`TEL: +81-955-78-1050
`
`QManufacturing Plant Fukusaki
`767-7, Saiji, Fukusakicho, Kanzaki-gun, Hyogo, 679-2285
`TEL: +81-790-22-2671
`
`.Kobe Creative Center
`1-5-4, Murotani, Nishi-ku, Kobe-shi, Hyogo, 651-2241
`TEL: +81-78-997-1010
`
`Osenju Laboratory of Ocular Science
`BMA
`1-5-5, Minatojimaminamimachi, Chuo-ku, Kobe-shi, Hyogo, 650-0047
`TEL: +81-78-303-4031
`
`Page 16 of 18
`
`
`
`P1'O d1lCtS (Overseas)
`
`I Asia
`
`China
`
`<>Pranopu|in (Senju)
`CCata|in (Senju)
`Bronuck (Senju)
`©Sodium Hyaluronate (Senju)
`*Talymus (Senju)
`
`South Korea
`
`<>Pranopu|in (JW Shinyak)
`i‘:Lomef|on (JW Shinyak)
`OTimobetalol-LA (Taejoon)
`Bronuck (Taejoon)
`ISenju CL (JW Pharma)
`IFrenz Eye Drops (JW Pharma)
`
`Hong Kong
`Ocatalin (Takeda Hong Kong)
`
`Taiwan
`
`Ocataiin K (Takeda Taiwan)
`
`Philippines
`Ocataiin (Takeda Philippines)
`
`Indonesia
`CCatalin (P.T. Takeda Indonesia)
`
`Thailand
`
`Pakistan
`
`Ocatalin (Takeda Thailand)
`
`CCatalin (Helix)
`
`Vietnam
`
`Bronuck (Senju)
`©Tearba|ance (Senju)
`
`India
`
`OG|ucotimLA (Centaur)
`Ocubro (Centaur)
`
`
`
`(szosxazxo)Slzmpoild
`
`I Americas
`
`United States
`
`Olstalol (B+L)
`Prolensa (B+L)
`Bromday (B+L)
`OBepreve (B+L)
`ODurezo| (Alcon)
`
`Mexico
`
`<>Nif|an (SIFI)
`
`Brazil
`
`Puerto Rico
`
`Oclarvisol (Allergan)
`
`ODurezo| (Alcon)
`
`Canada
`
`ODurezo| (Alcon)
`
`Bulgaria
`Yellox (Valeant)
`
`Hungary
`Yellox (Va|eant)
`
`Switzerland
`
`Yellox (valeant)
`
`Saudi Arabia
`
`CCata|in (Saudi Arabian Drug Store)
`
`I Europe and the Middle East
`
`Poland
`
`Ocatalin (Pharmaheads)
`Yellox (valeant)
`
`Russia
`
`CCata|in (Senju)
`
`Romania
`
`<>Pranoflog (SIFI)
`
`Belgium
`<>Pranox (MEDA)
`
`Portugal
`.C|arvisan (LUSO)
`Yellox (Va|eant)
`
`Italy
`OC|arvisan (Allergan)
`<>Pranoflog (SIFI)
`Yellox (valeant)
`
`Germany
`Yellox (Va|eant)
`
`United Kingdom
`Yellox (Va|eant)
`
`Austria
`
`Yellox (valeant)
`
`France
`
`Yellox (Va|eant)
`
`Netherlands
`
`Yellox (valeant)
`
`Republic of Ireland
`Yel ox (valeant)
`
`Sweden
`
`Yel ox (Valeant)
`
`Norway
`Yel ox (valeant)
`
`Denmark
`
`Yel ox (Va|ea nt)
`
`Finland
`
`Yel ox (valeant)
`
`Spain
`Yel ox (valeant)
`
`Product names in Japan: O CATALIN Ni‘: LOMEFLON <> NIFLAN Kl BRONUCK © TEARBALANCE * TALYMUS I Generic medicine 0 Not sold in Japan
`>l<()=Marketlng Authorization Holder
`
`As of July 2015
`
`Page 17 of 18
`
`
`
`Products (Japan)
`
`Prescription Products
`
`[Eye products]
`Inflammation and allergy
`ELICS OPHTHALMIC SOLUTION 0.25%
`ODOMEL OPHTHALMIC SOLUTION 0.02%
`ODOMEL OPHTHALMIC SOLUTION 0.05%
`ODOMEL OPHTHALMIC SOLUTION 0.1%
`CROMOFERON OPHTHALMIC SOLUTION 2%
`KETAS OPHTHALMIC SOLUTION 0.01%
`NIFLAN OPHTHALMIC SOLUTION 0.1%
`VISUALIN OPHTHALMIC SOLUTION 0.02%
`VISUALIN OPHTHALMIC SOLUTION 0.05%
`VISUALIN SOLUTION FOR EYE EAR AND NOSE 0.1%
`BRONUCK OPHTHALMIC SOLUTION 0.1%
`LYSOTEAR OPHTHALMIC SOLUTION 0.5%
`LEVOCABASTINE 0.025% OPHTHALMIC SOLUTION [TS]
`
`Antibacterial and antifungal agents
`GATIFLO OPHTHALMIC SOLUTION 0.3%
`BACCIDAL OPHTHALMIC SOLUTION 0.3%
`PIMARICIN 1% Ointment [SENJU]
`PIMARICIN OPHTHALMIC SOLUTION 5% [SENJU]
`BESTRON OPHTHALMIC SOLUTION 0.5%
`LOMEFLON OPHTHALMIC SOLUTION 0.3%
`LOMEFLON MINIMS SOLUTION FOR EYE AND EAR 0.3%
`
`Over the Counter (OTC) Products
`
`Eye medicine
`Mytear EYETECT
`Mytear EYETECT ALPITATTO
`Mytear EYETECT ALPITATTO-N
`Mytear ALPITATTO EXot
`Mytear ALPITATTO N EXa
`NewMytear A
`Mytearclean Cool
`Mytear Vitamin B2BsE
`Mytear Vido
`Mytear Fresh40
`
`Animal Medicines
`
`STEROP
`TEAROSE
`PAPITEIN
`MIMIENA
`LIGHT CLEAN
`LOMEWON
`ONE CLEAN
`
`
`
`(uzdzf)Slonpoxd
`
`Other
`ARTIFICIAL TEAR MYTEAR OPHTHALMIC SOLUTION
`SCOPISOL SOLUTION FOR EYE
`SOFTEAR OPHTHALMIC SOLUTION 0.02%
`TAZIN TABLETS 30
`TALYMUS OPHTHALMIC SUSPENSION 0.1%
`TEARBALANCE OPHTHALMIC SOLUTION 0.1%
`TEARBALANCE OPHTHALMIC SOLUTION 0.3%
`TEARBALANCE MINIMS OPHTHALMIC SOLUTION 0.3%
`
`[Ear, nose and throat products]
`VISUALIN SOLUTION FOR EYE EAR AND NOZE 0.1%
`BESTRON FOR EAR AND NOSE 1%
`LOMEFLON SOLUTION FOR EAR 0.3%
`LOMEFLON MINIMS SOLUTION FOR EYE AND EAR 0.3%
`
`Contact Lens Products
`
`03/hard use
`Mytear Hard Lens Wearing Solution (designated quasi-drug)
`NewMytear Easy S
`NewMytear CL 0; Lens Care
`
`Cataracts
`CATALIN FOR OPHTHALMIC 0.005%
`CATALIN-K FOR OPHTHALMIC 0.005%
`
`Glaucoma
`AIPHAGAN OPHTHALMIC SOLUTION 0.1%
`MIKELAN OPHTHALMIC SOLUTION 1%
`MIKELAN OPHTHALMIC SOLUTION 2%
`MIKELAN LA OPHTHALMIC SOLUTION 1%
`MIKELAN LA OPHTHALMIC SOLUTION 2%
`LATANOPROST OPHTHALMIC SOLUTION 0.005% SENJU
`LUMIGAN OPHTHALMIC SOLUTION 0.03%
`
`Surgical aids
`INDOMELOL OPHTHALMIC SOLUTION 0.5%
`OXYBUPROCAINE HYDROCHLORIDE MINIMS OPHTHALMIC SOLUTION 0.4“/I [SENJU]
`OPEGUARD-MA INTRAOCULAR IRRIGATING SOLUTION
`OPEGUARD Neo Kit INTRAOCULAR IRRIGATING SOLUTION 0.0184‘/o
`OPELEAD 0.5 OPHTHALMIC VISCOELASTIC PREPARATION 1%
`OPELEAD 0.6 OPHTHALMIC VISCOELASTIC PREPARATION 1%
`0PELEAD1.1 OPHTHALMIC VISCOELASTIC PREPARATION 1%
`OPELEAD HVO.4 OPHTHALMIC VISCOELASTIC PREPARATION 1%
`OPELEAD HVO,6 OPHTHALMIC VISCOELASTIC PREPARATION 1"/n
`OPELEAD HVO.85 OPHTHALMIC VISCOELASTIC PREPARATION 1%
`
`Eye medicine for use with contact lens
`NewMytear CL a
`NewMytear CL Cool a
`NewMytear CL Cool Hi a
`NewMytear CL Ice Crush
`FirstMytear CL-P
`FirstMytear CL-G
`FirstMytear CL-B
`
`Animal Quasi-Drugs
`
`BEST FRIENDS EAR CLEANER A
`BEST FRIENDS EAR CLEANER G
`
`Animal Health Products
`
`BEST FRIENDS RINSE IN SHAMPOO
`BEST FRIENDS TREATMENT MIST TYPE
`
`As of July 2015
`
`Page 18 of 18