CURRICULUM VITAE
`
`John Frank Carpenter
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`Office Telephone:
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`303-724-6110
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`I. GENERAL INFORMATION
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`Office Address: Department of Pharmaceutical
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` Sciences
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`12700 East Montview Blvd. C238
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`University of Colorado Denver
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`Anschutz Medical Campus
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`Aurora, CO 80045
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`II. EDUCATION
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`III. PROFESSIONAL EXPERIENCE
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`YEAR
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`1978
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`1981
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`INSTITUTION
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`Duke University
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`DEGREE OBTAINED
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`B.S., Zoology
`(Magna cum laude)
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`Oregon State University M.S., Zoology
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`(Biochemistry minor)
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`1985
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`Univ. of Louisiana, Lafayette Ph.D., Biology
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`YEAR
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`1978-1981
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`1981-1982
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`1982-1985
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`1986-1988
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`1988-1992
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`TITLE
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`Graduate Student
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`Hatchery Manager
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`Graduate Student
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`INSTITUTION
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`Oregon State University
`(Dept. of Zoology)
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`Laguna Madre Shrimp Farm
`Harlingen, TX
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`Univ. of SW Louisiana
`(Biology Department)
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`Postdoctoral Associate
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`Univ. of California, Davis
`(Zoology Department)
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`Senior Scientist
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`CryoLife, Inc.
`Marietta, GA
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`Page 1
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`NPS EX. 2043
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`IV. ACADEMIC APPOINTMENTS
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`YEAR
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`1987-1988
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`1993-1998
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`1993-present
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`1997-present
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`1997-present
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`1998-2004
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`2000-present
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`2001-present
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`2003-2008
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`2004-present
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`TITLE
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`Visiting Lecturer
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`INSTITUTION
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`Univ. of California, Davis
`
`
`Assistant Professor of
`Pharmaceutical Biotechnology
`
`University of Colorado
`
`Graduate Faculty
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`Univ. of Colorado Health
`Sciences Center
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`Co-Founder and Co-Director University of Colorado
`Center for Pharmaceutical
`Biotechnology
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`Graduate Faculty
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`
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`Univ. of Colorado, Boulder
`
`Univ. of Colorado HSC
`
`Associate Professor
`of Pharmaceutical Biotechnology
`
`
`Associate Director
`Pharmaceutical Biotechnology
`Graduate Training Program
`
`Co-Director, NIH Training
`Grant, Leadership Training in
`Pharmaceutical Biotechnology
`
`
`
`Director
`Pharmaceutical Biotechnology
`Graduate Training Program
`
`Univ. of Colorado HSC
`
`Univ. of Colorado
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`Univ. of Colorado HSC
`
`Univ. of Colorado HSC
`
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`Professor
`of Pharmaceutical Biotechnology
`
`2012-present
`
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`
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`
`
`Director of Business
`Development
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`Univ. of Colorado Skaggs School of
`Pharmacy and Pharmaceutical Sciences
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`V. CONSULTING ACTIVITIES
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`Consultant for:
`
`Baxter Diagnostics, Miami, FL
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`2
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`Page 2
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`W.R. Grace Co., Boston, MA
`Alza Corporation, Palo Alto, CA
`Somatogen, Boulder, CO
`Neurobiological Technologies, Richmond, CA
`Boehringer Mannheim Therapeutics, Mannheim, Germany
`Inhale Therapeutics, Palo Alto
`Biogen, Cambridge, MA
`Dade International, Miami, FL
`Cytoskeleton, Inc., Denver, CO
`Baxter Healthcare, Inc., Duarte, CA
`Pfizer, Inc., Groton CT and St. Louis, MO
`Igen International, Inc., Gaithersburg, MD
`Idexx, MN
`Vitro Diagnostics, Inc., Littleton, CO
`Chiron, Emeryville, CA
`PowderJect Technologies, Inc.
`Elan Pharmaceuticals, Miramar, FL
`Iomai, Washington, DC
`Speywood Pharmaceuticals, UK
`Dade Behring, Newark, DE
`Becton Dickinson Technologies, Research Triangle Park, NC
`Regeneron, Tarrytown, NY
`Organ Recovery Systems, Charleston, SC
`IDEC, San Diego, CA
`NaPro, Boulder, CO
`RxKinetix, Louisville, CO
`Johnson and Johnson
`Ferro Pfanstiehl,
`CTI, Seattle, WA,
`HTD Biosystems, Denver, CO
`Orbus, Ft. Lauderdale, FL
`SeaRun Holdings, MN
`Baxter Healthcare, Deerfield, IL
`Eli Lilly, Indianapolis, IN
`Seattle Genetics, Seattle, WA
`GlobeImmune, Aurora, CO
`BaroFold, Boulder, CO
`Insmed, Inc., Boulder, CO
`BristolMeyersSquibb
`Xoma, San Francisco, CA
`AktivDry, Boulder, CO
`Potentia Pharmaceuticals, Louisville, KY
`Teva Pharmaceuticals, Ltd., Petach Tikva, Israel
`VaxGen, San Francisco, CO
`Acambis, Boston, MA
`Seattle Genetics, Seattle, WA
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`3
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`Page 3
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`Transform Pharmaceutical, Boston, MA
`Centocor, San Francisco, CA
`Revance, San Diego, CA
`Cellerant, San Carlos, CA
`Abaxis, San Jose, CA
`Merck, Whitehouse Station, NJ
`Sanofi, New York, NY
`St. Teresa’s Medical Center
`NPS Pharmaceuticals, Philadelphia, PA
`MedImmune, Bethesda, MD
`Versartis, Menlo Park, CA
`Novo Nordisk, Bagsvaerd, Denmark
`
`Member of Scientific Advisory Board for:
`
`
`
`Integrated Biosystems
`RxKinetix
`Becton Dickinson
`Governor’s Council on Biotechnology, Colorado
`AktivDry
`RedStorm Scientific
`IntegrityBiosolution
`BaroFold
`Coriolis Pharma
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`VI. TEACHING ACTIVITY
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`YEAR COURSE
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` CONTACT HRS
` SEMESTER NO. OF
` CREDITS
` STUDENTS
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`University of California, Davis
`
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`3
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`3
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`180
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`180
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`45 lecture
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`45 lecture
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`1987 Human Physiology
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`1988 Human Physiology
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`1993 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
`
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`University of Colorado (*Course Coordinator)
`
`
`
`4
`
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`130
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`60 lecture
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`4
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`Page 4
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`

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`70
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` 12
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`7 lecture
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`6 lecture
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`30 lecture
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`7 lecture
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`10 lecture
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`30 lecture
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`30 lecture
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` 5 lecture
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` 5 lecture
`
`105
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`70
`
`12
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`105
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` 90
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` 50
`
` 6
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`2.7
`
`4
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`4
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`4
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`4
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`4
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`
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`
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`
`
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`4
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`4
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`4
`
`3
`
`5
`
`1993 PHSC 7656 Advanced
` Pharmaceutics
`
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`1994 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
`
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`1994 PHSC 7800 Molecular Biol.
`
`1995 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
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`1995 PHSC 7800 Molecular Biol.
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`1996 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
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`1996 *PHSC 7341 Graduate Physiology
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`1996 PHSC 7800 Molecular Biol.
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`1997 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
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`1997 PHSC 7800 Molecular Biol.
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`1997 Pharm.D. Pathophysiology
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`1997 Graduate Protein Chemistry
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`1997 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
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`1998 Pharm.D. Pathophysiology
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`1998 Graduate Protein Chemistry
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`1998 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
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`1999 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
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`1999 Track-In Pharm.D.
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`Pathphys.
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`1999 Grad. Protein Chem.
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`1.3
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`4
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`2.7
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`4
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`2.7
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`4
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`2
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`2.7
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`4
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`3
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`140
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`40
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`135
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`30
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`135
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`6
`
`35
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`125
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`50
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`4 lecture
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`60 lecture
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`2 lecture
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`50 lecture
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`2 lecture
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`50 lecture
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`30 lecture
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`4 lecture
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`40 lecture
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`4 lecture
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`Page 5
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`2000 Track-In Pharm.D.
`
`Pathphys.
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`2000 *PHSC 3410 Physiology/
` Pathophys. for Therapeutics
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`2001 Integrated Organ Systems I
`
`Physiology
`
`2001 Grad. Protein Chem.
`
`2002 *Integrated Organ Systems I
`
`Physiology
`
`2002 Intergrated Organ Systems IV
`
`Pathophysiology
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`2002 *Grad. Issues in Drug Develop.
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`2003 *Grad. Protein Formulation
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`2003 *Integrated Organ Systems I
`
`Physiology
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`2003 Grad. Protein Chem.
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`2004 Integrated Organ Systems I
`
`Physiology
`
`2005 Integrated Organ Systems I
`
`Physiology
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`2005 Grad. Protein Chem.
`
`2006 *Grad. Issues in Drug Development
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`2007 Integrated Organ Systems I
`
`Physiology
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`2007 *Grad. Protein Formulation
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`2007 Grad. Protein Chem.
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`2008 Integrated Organ Systems I
`
`Physiology
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` 6
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`130
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`130
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` 12
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` 10
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`130
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` 14
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` 12
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` 130
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`14 lecture
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`14 lecture
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` 3 lecture
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` 4 lecture
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`14 lecture
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`36 lecture
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` 3 lecture
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`14 lecture
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`3
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`4
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`4
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`3
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`2
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`4
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`2
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`3
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`4
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`6
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`4
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`4
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`4
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`3
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`4
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`4
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`2
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`2
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`4
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` 50
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` 90
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` 90
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` 6
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`110
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` 90
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` 12
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` 10
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`110
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` 5 lecture
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`15 lecture
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`14 lecture
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` 5 lecture
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`14 lecture
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` 4 lecture
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` 2 lecture
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`28 lecture
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`14 lecture
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` 5 lecture
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`Page 6
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`

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`3
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`4
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`3
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`2
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`4
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`3
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`4
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`2
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` 12
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` 150
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` 12
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` 14
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` 150
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` 12
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` 160
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` 14
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` 3 lecture
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`14 lecture
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` 3 lecture
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`36 lecture
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`14 lecture
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`3 lecture
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`14 lecture
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`36 lecture
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`
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`3 lecture
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`2008 Grad. Protein Chem.
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`2009 Integrated Organ Systems I
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`Physiology
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`2009 Grad. Protein Chem.
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`2009 *Grad. Protein Formulation
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`2010 Integrated Organ Systems I
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`Physiology
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`2010 Grad. Protein Chem.
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`2011 Integrated Organ Systems I
`
`Physiology
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`2011 *Grad. Protein Formulation
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`2011 Grad. Protein Chem.
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`2012 Applied Biochemistry
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`2012 Grad. Protein Chem.
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`2013 Applied Biochemistry
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`2013 Grad. Protein Chem.
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`2014 *Grad. Protein Formulation
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`2014 Applied Biochemistry
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` 12
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`170
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` 12
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`170
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` 12
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` 6
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`170
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`4 lecture
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`3 lecture
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`4 lecture
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`3 lecture
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`36 lecture
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`4 lecture
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`3
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`4
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`3
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`4
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`3
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`2
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`4
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`Other
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`Lecturer, "Principles of Physiology", School of Pharmacy Minority Student Summer
`Orientation Program, 1994
`Lecturer, "Principles of Physiology", School of Pharmacy Minority Student Summer
`Orientation Program, 1995
`Lecturer, "Principles of Physiology", School of Pharmacy Minority Student Summer
`Orientation Program, 1996
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`7
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`Page 7
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`Lecturer, "Principles of Physiology", School of Pharmacy Minority Student Summer
`Orientation Program, 1997
`Invited Lecturer, Parenteral Drug Association Workshop on "Formulating Stable
`Biotechnology Products", New Brunswick, NJ, 1995
`Invited Lecturer, Conference on Pharmaceutical Science and Technology Workshop on
`"Formulating Stable Protein Pharmaceutical Products", Chicago, IL, 1995
`Invited Lecturer, Parenteral Drug Association Workshop on "Formulating Stable
`Biotechnology Products", San Diego, 1995
`Co-Organizer and Co-Chair (with Drs. Ted Randolph and Mark Manning), "Annual
`Graduate Student Symposium in Pharmaceutical Biotechnology", 1995-1997
`Lecturer and Organizer, "A Hands-On Course on Analysis of Protein Structure with
`Infrared Spectroscopy", Denver, CO, 1998
`Lecturer and Co-organizer, “Protein Formulation Development Shortcourse”, Breckenridge, CO,
`2002, 2003, 2005
`Guest Lecturer, “Analytical Chemistry, Colorado School of Mines, 2011, 2012
`
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`VII. ADVISING ACTIVITY
`
`Thesis Advisor for Ph.D. Students
`
`University of Colorado, Department of Pharmaceutical Sciences
`
`S. Dean Allison (Ph.D., 1998)
`Brent Kendrick (Ph.D., 1997)
`Kathy Pikal (Ph.D., 1999)
`LaToya Jones (Ph.D., 2001)
`Sumpathkumar Krishnan (Ph.D., 2002)
`Yong-sung Kim (Ph.D., 2002)
`Sandhya Buchanan (Ph.D., 2006)
`Tia Estey (Ph.D., 2006)
`Shouvik Roy (Ph.D., 2006)
`Chris Vesseley (Ph.D., 2006)
`Derrick Katayama (Ph.D., 2006)
`Renuka Thirumangalathu (Ph.D., 2007)
`Danny Chou (Ph.D., 2008)
`Shujun Bai (Ph.D., 2008)
`Mary Cromwell (Ph.D., 2008)
`James Barnard (Ph.D., 2013
`Pinaki Basu (2005-present)
`Luke Liu (2005-present)
`Brandon Teska (2008-present)
`Neha Pardeshi (2008-present)
`Merry Le (2009-present)
`Shyam Mehta (2010-present)
`Chen Zhou (2012-present)
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`8
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`Page 8
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`Aditya Ghandi (2014-present)
`
`Other Institutions
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`Lotte Krielgard, Royal Danish School of Pharmacy, Co-Advisor, (Ph.D., 1998)
`Liza Nielsen, Royal Danish School of Pharmacy, Co-Advisor, (Ph.D., 2002)
`Susanne Sondekar, Royal Danish School of Pharmacy, Co-Advisor, (Ph.D., 2003)
`
`
`Mentor for Postdoctoral Research Associates
`
`Richard Remmele, Ph.D.
`Aichun Dong, Ph.D.
`Thomas Anchordoquy, Ph.D.
`Tzung-Horng Yang, Ph.D.
`Suchart Chongprasert, Ph.D.
`Scott Sellers, Ph.D.
`William Garzon-Rodriguez, Ph.D.
`Steve Cape, Ph.D.
`Liza Kueltzo, Ph.D.
`Anil Tyagi, Ph.D.
`Dilip Devineni, Ph.D.
`Swati Bandi, Ph.D.
`Weijie Fang, Ph.D.
`Pradyot Nandi, Ph.D.
`Wei Qi, Ph.D.
`Aaron Krueger, Ph.D.
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`VIII. ADMINISTRATIVE ACTIVITY AND UNIVERSITY SERVICE
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`
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`DOPS Research Committee, 1995-2000
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`Graduate Program Committee, 1993-1996
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`Continuing Education Committee, 1993-1994
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`Core Course ad hoc Committee, 1993
`
`DOPS Seminar Committee, Co-Chair, 1993-1994, 1997
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`UCHSC Technology Transfer Committee, 1997-1999
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`SOP Scholastic Advancement Affairs Committee, 1997-1999
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`UCHSC Indirect Cost Waiver Committee, 1998-2000
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`DOPS Faculty Search Committee, 1997, 1998, 1999, 2000, 2002, 2003, 2008, 2010
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`UCHSC Diversity Committee, 1998-2000
`
`CU Intellectual Property Committee, 1999-2009
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`Chair, SOP Students Ethics and Conduct Committee, 1999-2000
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`Member, SOP Space Committee, 2000
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`Member, CU Technology Transfer Advisory Board, 2002-2005
`
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`Member, Fitzsimons Biosciences Park Advisory Board, 2002-2009
`
`Member, DOPS Advancement, Promotion and Tenure Committee, 2003-2010, 2013-
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`9
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`Page 9
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`Member, UCDHSC Indirect Cost Waiver Committee, 2005-2009
`Member, SOP Building Committee, 2007-2009
`Member, Search Committee, Vice Chancellor for Research, UC AMC, 2009
`Chair, Dean’s APT Committee, 2011, 2013
`Member, SOP Assessment Committee, 2011-present
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`IX. HONORS
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`
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`Fellow, American Association for Advancement of Science, 2009
`Research Achievement Award in Biotechnology, American Association of Pharmaceutical
`
`Scientists, 2007
`Ebert Prize, APhA, Journal of Pharmaceutical Sciences, 2007
`
`Ken Avis Distinguished Visiting Professor, Univ. of Tennessee College of Pharmacy, 2005
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`Keynote Speaker, Univ. of Minnesota Drug Delivery Center Open House, 2004
`
`Fellow, American Association of Pharmaceutical Scientists, 2002
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`Keynote Speaker, ACS Colorado Student Awards Banquet, 1999
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`Chancellor's Teaching Recognition Award, UCHSC Graduate School, 1998
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`Excellence in Teaching Award, University of Colorado School of Pharmacy, 1998
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`Eli Lilly Young Investigator in Pharmaceutical Sciences Award, 1998-1999
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`Plenary Lecturer, Colorado Institute for Research in Biotechnology Meeting, 1995
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`Excellence in Teaching Award, University of Colorado School of Pharmacy, 1995
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`Excellence in Teaching Award, University of Colorado School of Pharmacy, 1994
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`Keynote Address, American Chemical Society National Meeting, 1994
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`Excellence in Teaching Award, University of Colorado School of Pharmacy, 1993
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`
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`X. PROFESSIONAL ACTIVITY AND PUBLIC SERVICE
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`A. Membership in Professional Organizations
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`American Association of Pharmaceutical Scientists (AAPS)
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`American Association for the Advancement of Science (AAAS)
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`B. Service in Professional Organizations
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`Member, Finance Committee, Society for Cryobiology, 1990-1993
`Treasurer, Society for Cryobiology, 1991-1993
`Member, Executive Committee, Society for Cryobiology, 1991-1993
`Member, Program Committee, Society for Cryobiology, 1993-1994
`Member, Board of Governors, Society for Cryobiology, 1993-1995
`Chair, Finance Committee, Society for Cryobiology, 1993-1995
`Member, Publications Committee, Society for Cryobiology, 1996-1997
`Member, BIOTEC Section Fellows Committee, AAPS, 1996
`Member, BIOTEC Section Program Committee, AAPS, 1996
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`Page 10
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`Member, Education Committee, AAPS, 1996
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`Member, Organizing Committee, AAPS Western Regional Meeting, 1997
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`Member, Publicity Committee, World Millenial Conference on Pharmaceutical
`
`
`Sciences, 1999-2000
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`Member, BIOTEC Section Fellows Committee, AAPS, 2003
`
`Member, AAPS Publications Advisory Board, 2003-2006
`
`Chair, AAPS Books Subcommittee, 2004-2009
`
`Chair, BIOTEC Section Fellows Committee, AAPS, 2004
`
`Member, BIOTEC Section Fellows Committee, AAPS, 2005
`
`Member, Steering Committee, AAPS Aggregation and Biological Consequences Focus
`
`Group, 2006-2007, 2010- present
`
`Chair, President’s Task Force on Global Health, AAPS, 2007-2009
`
`Chair, Steeting Committee, AAPS Pharmaceutics in Global Health Focus Group, 2009-
`
`2011
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`C. Journal Referee
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`The AAPS Journal
`American Journal of Physiology
`American Chemical Society Symposium Series
`American Journal of Drug Delivery
`American Zoologist
`Analytical Biochemistry
`Archives of Biochemistry and Biophysics
`Archives of Insect Biochemistry and Physiology
`Biochima et Biophysica Acta
`Biochemistry
`Biochemistry and Cell Biology
`BioPharm
`Biophysical Chemistry
`Biophysical Journal
`Biopolymers
`Biopolymers: Peptide Science
`BioTechniques
`Biotechnology and Bioengineering
`Biotechnology Progress
`Carbohydrate Chemistry
`Comparative Biochemistry and Physiology
`Cryobiology
`Cryo-Letters
`Drug Development and Industrial Pharmacy
`European Journal of Biochemistry
`European Journal of Pharmaceutics and Biopharmaceutics
`International Journal of Pharmaceutics
`Journal of Agriculture and Food Chemistry
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`11
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`Page 11
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`Journal of Biological Chemistry
`Journal of Controlled Release
`Journal of Experimental Biology
`Journal of Experimental Zoology
`Journal of Molecular Biology
`Journal of Pharmaceutical Sciences
`Journal of Physical Chemistry
`Nature Eye
`Pharmaceutical Research
`PharmSci
`PharmSciTechnology
`Photochemistry and Photobiology
`The Plant Journal for Cell and Molecular Biology
`Proceedings of the National Academy of Sciences
`Protein Engineering
`Protein Engineering, Design and Selection
`Protein Science
`Proteins
`
`D. Grant Review Panels
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`Alzheimer's Association, 2001
`National Science Foundation, ad hoc Reviewer
`
`Molecular Biophysics, 1993-1995
`
`Physiological Ecology, 1994-1995
`
`Biochemistry & Molecular Structure and Function, 1994-1995
`
`Integrative Plant Biology, 1995
`
`Ecological and Evolutionary Physiology, 1996, 1998
`
`Antarctic Biology and Medicine, 1996, 2000
`
`Bioengineering and Environmental Sciences, 1999, 2009
`
`Arctic Natural Sciences, 2003, 2010
`Office of Naval Research, ad hoc Reviewer, 1994
`Sea Grant Program, ad hoc Reviewer, 1993-1994
`Colorado Institute in Biotechnology, 1995, 1999
`USAMRMC Breast Cancer Research Program, Research with Translational
` Potential Study Section, 1996
`National Institutes of Health, NIGMS, ad hoc Reviewer, 1997
`American Association of Colleges of Pharmacy, New Investigator Awards, 2003
`
`E. Editorial Boards
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`Cryobiology, 1991-2005
`Journal of Pharmaceutical Sciences, 1994-present
`Journal of Pharmaceutical Sciences, Editor for Reviews and Commentaries, 2005-
`present
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`12
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`Page 12
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`Pharmaceutical Research, 1997-present
`
`BioPharm, 1998-present
`
`AAPS PharmSci, 1999-2005
`
`Current Pharmaceutical Biotechnology, 1999-present
`
`Cell Preservation Technology, Associate Editor, 2002-2006
`
`Molecular Pharmaceutics, 2003-present
`
`Journal of Biological Chemistry, 2003-2008
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`F. Other
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`Co-Organizer and Co-Chair (with Prof. Serge Timasheff), "Workshop on Protein
`
`Stability", Annual Meeting of Cryobiology Soc., Leuven, Belgium, 1991
`Co-Organizer and Co-Chair (with Profs. John Crowe, George Somero, James
`
`
`Clegg), "Compatible Solutes and Macromolecular Stability: A Colloquium
`
`of the Bodega Bay Marine Laboratory", Bodega Bay, CA, 1992
`Member, Organizing Committee, Annual Meeting of Cryobiology Society,
`
`Atlanta, GA, 1993
`Organizer and Chair, "Session on Protein Storage Stability", BioPharm
`
`Conference, San Francisco, CA, 1994
`Co-Organizer and Co-Chair (with Ted Randolph et al.), "Colorado
`Protein Stability Conference", 1994, 1996, 1998, 2000, 2002, 2003, 2005, 2007,
`2009, 2011, 2013, 2015
`Co-Organizer and Co-Chair (with Dr. Michael Pikal), "Symposium on Protein
`
`Lyophilization", American Chemical Society Conference on Formulations
`
`
`and Drug Delivery, Boston, MA, 1995
`Member, Program Committee, "1995 Conference on Pharmaceutical Science and
`
`Technology" in conjunction with the 1995 International Conference
`
`on Food Science and Technology and the 26th Annual Meeting of the Fine
`
`
`Particle Society
`Co-Host (with Mark Manning), Visiting Professor, Prof. Lewis Stratton, Chair,
`
`Dept. of Biology, Furman University, 1995-1996
`Host, Visiting Scholar, Dr. Ken-ichi Izutsu, National Institute of Health Sciences,
`
`
`Tokyo, Japan, 1995-1997
`Co-Organizer and Co-Chair (with Dr. Ted Randolph), "Symposium on Protein
`
`Stabilization", American Chemical Society National Meeting, New
`
`Orleans, LA, 1996
`Member, Organizing Committee, American Chemical Society Conference on Drug
`
`Stability and Delivery, San Diego, 1997
`Chair, Fund Raising Committee, American Chemical Society Conference on Drug
`
`
`Stability and Delivery, San Diego, 1997
`Co-Organizer, "Colorado Biopharmaceutical Delivery Conference", 1997
`Co-Organizer and Co-Chair, Session on Protein Formulation, American Chemical
`
`
`Society Conference on Drug Stability and Delivery, San Diego, 1997
`Co-Organizer and Co-Chair, Symposium on Protein-Excipient Interactions,
`
`
`Western Regional AAPS Meeting, San Francisco, CA, 1998
`Member, Publicity Committee, World Millennial Pharmaceutics Conference, 1999
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`13
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`Page 13
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`Organizer, Student Lunch and Learn Session on Industrial Careers, AAPS
`
`
`National Meeting, Boston, MA, 1997
`
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`Member, Organizing Commitee, Conference on Biopharmaceutical Lyophilization,
`
`Vermont, 1998
`Organizer, Session on Advanced Analytical Methods, BioPharm Conferences, East
`
`(Boston) and West (San Francisco), 1999
`Organizer, Session on Formulation of Biopharmaceuticals for Delivery Systems,
`
`
`BioPharm Conferences, East (Boston) and West (San Francisco), 1999
`Co-Organizer, Macromolecular Drug Delivery Conference, Breckenridge, CO,
`
`1999, 2001
`Co-Organizer, DARPA Conference on Stabilization of Dried Biomaterials,
`
`Breckenridge, CO, 1999
`Organizer, Symposium on Protein Powders, AAPS Drug Delivery Conference
`
`Alexandria, VA, 2002
`Co-Organizer, IBC Conference on Protein Formulations, Philadelphia, 2003
`Organizer and Session Chair, Protein Formulation Symposium, Protein Society Annual
`
`Meeting, San Deigo, CA, 2004
`Member, Organizing Committee, Meeting Host, Workshop of Protein Aggregation and
`
`Immunogenicity, Breckenridge, CO, 2006, 2010, 2012, 2014
`Member, Organizing Committee, IABS Workshop on Protein Particles, Washington,
`DC, 2009
`Organizer, Protein Formulation Symposium, Annual Meeting of the Protein Society,
`
`San Diego, 2010
`Member, Organizing Committee, CASS Higher Order Structure Conference,
`
`Baltimore, MD, 2011, 2012, 2014
`Member, Organizing Committee, Workshop on Protein Particles and
`
`Immunogenicity, Bethesda, MD, 2011
`Member, Board of Directors, Haitian Timoun Foundation, 2011-present
`
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`XI. GRANT ACTIVITY
`
`Current Grant Funding:
`
`MedImmune, 2004-2016, $1,480,000
`PI’s: John Carpenter and Ted Randolph
`“Solubility and Aggregation of Monoclonal Antibodies”
`
`
`
`NIH Partnership in Bioengineering, 2013-2018, $600,000 for Carpenter lab
`
`PI’s: Ted Randolph, John Carpenter, Chris Roberts, Carol Hall
`
`“Protein Aggregation and Its Inhibition”
`
`Malvern, 2013-2016, $425,000
`
`PI: John Carpenter
`
`“Characterization of Protein Stability and Aggregation with State-of-the-art
`
`Biophysical and Particle Counting Instruments”
`
`14
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`Page 14
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`Gore Biomedical, 2013-2015, $145,000
`
`PI: John Carpenter
`“Effects of Novel Syringe and Stopper on Protein Aggregation and Particle
`Formation”
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`
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`Grants Approved for Funding:
`
`
`Previous Grant Funding:
`
`SBIR Phase I Grant, Office of Naval Research, 1989-1990, $ 48,125
`
`PI: John Carpenter
`
`"Novel Cryopreservation Technique for Human Red Blood Cells using
`
`Recombinant Antifreeze Peptide"
`
`
`
`Office of Naval Research, 1991-1994, $ 837,500
`
`PI: John Carpenter
`
`"Cellular Damage during Non-Freezing Cold Injury"
`
`SBIR Phase I Grant, NIH, 1991, $ 50,000
`
`Co-PI's: John Carpenter and Dr. Kelvin Brockbank
`
`"Novel Cryopreservation Technique for Bone Marrow Cells using Antifreeze Peptide"
`
`Baxter Diagnostics, Inc., 1993, $15,000
`
`PI: John Carpenter
`
`"Stabilization of Air-Dried Enzymes"
`
`Genentech, Inc., 1993, $10,000
`
`PI: John Carpenter
`
`"Infrared Determination of Protein Structure During Freeze-Thawing"
`
`Colorado Institute for Research in Biotechnology and BioStar, Inc., 1993-94, $30,000
`
`PI: John Carpenter
`
`"Application of Principals of Protein Stabilization to Surface-Adsorbed Antibodies"
`
`Office of Naval Research, 1994-1996, $419,484
`
`PI: John Carpenter
`
`"Effects of Lyophilization of Metabolic Integrity of Red Blood Cells"
`
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`15
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`Shimadzu, 2015-2016, $90,000
`
`PI’s: Ted Randolph and John Carpenter
`
`“Effects of Nanobubbles on Protein Aggregation and Immunogenicity”
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`Page 15
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`Scios Nova, Inc, 1994, $1250
`
`Co-PI's: John Carpenter and Dr. Mark Manning
`
`"Spectroscopic Studies on ANF-like Peptides"
`
`Synergen, Inc., 1994, $2,000
`
`PI: John Carpenter
`
`"Effect of Lyophilization on Protein Structure"
`
`Colorado Institute for Research in Biotechnology and Somatogen, Inc., 1994-95, $30,000
`
`Co-PI's: Dr. Theodore Randolph and John Carpenter
`
`"Stabilization of Recombinant Hemoglobin"
`
`Genentech, Inc., 1994-1995, $25,000
`
`Co-PI's: John Carpenter and Dr. Theodore Randolph
`
`"Protein/polymer Phase Separation during Freezing and Drying"
`
`Zymogenetics, Inc., 1994-1996, $10,000
`
`PI: John Carpenter
`
`"Storage Stability of Protein Drugs"
`
`Cytel Corporation, 1994-1995, $15,000
`
`Co-PI's: Dr. Mark Manning and John Carpenter
`
`"Structural Basis for the Activity of CY-1899"
`
`The Whitaker Foundation for Biomedical Engineering, 1995-1998, $180,000
`
`Co-PI's: Dr. Theodore Randolph and John Carpenter
`"Stabilization of Hemoglobin by Polymers during Freezing, Drying and Rehydration:
`FTIR and EPR studies"
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`National Science Foundation, 1995-1998, $400,000 plus $850,000 in matching support
`
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`from Eli Lilly, Merck, Genentech, Amgen, Immunex and Alza.
`
`
`Co-PI's: John Carpenter, Dr. Theodore Randolph and Dr. Jeffrey Cleland
`
`
`"Stabilization of Proteins by Polymers during Freezing, Drying and Rehydration:
`
`
`FTIR and EPR studies"
`
`National Science Foundation, 1995-1998, $400,000
`
`Co-PI's: Dr. Charles Glatz, Dr. Maurice Larson, Dr. Richard Honzatko,
`
`Dr. Theodore Randolph and John Carpenter
`
`"High Pressure Investigation of Protein Crystallization"
`
`Colorado Institute for Research in Biotechnology and Cytoskeleton, Inc., 1995-1996, $30,000
`
`PI: John Carpenter
`
`"Development of Stable Lyophilized Formulations of Actin and Tubulin"
`
`Berlex Drug Development and Technology, 1995, $1900
`
`PI: John Carpenter
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`Page 16
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`"Infrared Spectroscopic Studies of Protein Structure"
`
`R.W. Johnson Research Institute, 1995, $1900
`
`PI: John Carpenter
`
`"Infrared Spectroscopic Studies of Protein Structure"
`
`Matrix Pharmaceuticals, 1995, $500
`
`PI: John Carpenter
`
`"Infrared Spectroscopic Analysis of Structure in Collagen Formulations"
`
`Inhale Therapeutics, 1995, $8000
`
`PI: John Carpenter
`"Infrared Spectroscopic Studies of Effects of Formulation and Storage Conditions on
`Structure of Spray-dried Proteins"
`
`Boehringer Mannheim Therapeutics (Germany), 1995, $9000
`
`PI: John Carpenter
`"Infrared Spectroscopic Analysis of Effects of Formulation on Structure of Freeze-Dried
`Proteins"
`
`Genetics Institute, 1995, $3000
`
`PI: John Carpenter
`
`"Infrared Spectroscopic Analysis of Effects of Formulation on Structure of Freeze-
`
`Dried Proteins"
`
`Neurobiological Technologies, Inc., 1995, $5000
`
`Co-PI's: John Carpenter and Mark Manning
`
`"Structure and Activity of Human CRF"
`
`Genetics Institute, 1996-2000, $94,000
`
`PI: John Carpenter
`"Effect of Excipients on Freezing- and Drying-Induced Denaturation of Protein
`
` Drugs"
`
`
`Inhale Therapeutics, 1996-1997, $20,000
`
`PI: John Carpenter
`
`"Effect of Excipients and Storage Conditions on Structure of Spray-dried Proteins"
`
`Genentech, Inc., 1996-1997, $20,000
`
`Co-PI's: John Carpenter and Dr. Theodore Randolph
`
`"Stabilization of Proteins during Freezing and Drying"
`
`Boehringer Mannheim Therapeutics (Germany), 1996-1997, $82,000
`
`PI: John Carpenter
`
`"Optimizing Long-Term Storage Stability of Lyophilized r-PA Formulations"
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`Page 17
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`National Institutes of Health, SBIR Program, 1996, $5,000 for JFC lab
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`(Collaborator on grant by Dr. Kim Middleton of Cytoskeleton, Inc.)
`
`"Development of Products for Investigating the Cytoskeleton"
`
`Colorado Institute for Research in Biotechnology and Amgen, Inc., 1996-1997, $37,500
`
`Co-PI's: Dr. Ted Randolph and John Carpenter
`
`"High Pressure Refolding of Inclusion Bodies"
`
`Genentech, Inc., 1996-2000, $75,000
`
`PI: John Carpenter
`
`"Infrared Spectroscopic Investigation of Protein Structure in Drug Delivery
`
`Matrix"
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`
`
`Genencor, Inc., 1996-2003, $180,000
`
`Co-PIs: John Carpenter and Ted Randolph
`
`"Effects of Excipients on Liquid and Solid-State Stability of Subtilisin"
`
`NATO Scientific Affairs Division, 1996-1997, $6000 for international travel
`
`(Co-PI's: John Carpenter, Dr. A. Auffret and Dr. F. Franks, Pafra, Cambridge, UK)
`
`"Stabilization and Modification of Protein Structure by Vitrification"
`
`Novo Nordisk (Denmark), 1996, $7000
`
`PI: John Carpenter
`
`"Infrared Spectroscopic Studies of Protein Structure in Therapeutic Formulations"
`
`Boehringer Mannheim Therapeutics (Germany), 1996-1998, $87,500
`
`Co-PI's: John Carpenter and Dr. Theodore Randolph
`
`"Mechanisms of Protein Stabilization by Nonionic Surfactants"
`
`Colorado Institute for Research in Biotechnology and Amgen, Inc., 1997-1998, $57,500
`
`plus $50,000 match in supplies and analysis
`
`Co-PI's: John Carpenter and Ted Randolph
`
`"Mechanisms of Protein Stabilization by Nonionic Surfactants"
`
`Baxter Hyland, 1997-1998, $20,000
`
`PI: John Carpenter
`
`"Thermal and Infrared Spectroscopic Analyses of Lyophilized Formulations"
`
`Bayer Plasma Fractionation, 1997-1998, $46,380
`
`Co-PI's: Dr. Mark Manning and John Carpenter
`
`"Stability of Human Serum Albumin during Processing"
`
`Biogen, 1997-1998, $9000
`
`PI: John Carpenter
`
`"Infrared Spectroscopic Analysis of Lyophilized Protein Formulations"
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`Page 18
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`Alza Corporation, 1997, $25,000
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`Co-PI's: John Carpenter and Dr. Mark Manning
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`"Exclusive Sponsorship of the Colorado Biopharmaceutical Delivery Conference"
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`Amgen, Inc, 1998-2010, $770,000
`
`Co-PI's: John F. Carpenter and Dr. Ted Randolph
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`"Mechanisms for Protein Stabilization by Excipients"
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`National Science Foundation Merit Renewal, 1999-2001, $400,000
`
`Co-PI's: John Carpenter and Dr. Ted Randolph
`
`"Mechanisms for Success and Failure of Excipients as Protein Stabilizers"
`
`PowderJect, 1999-2000, $50,000
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`Co-PI's: Dr. Ted Randolph and John Carpenter
`
`"Production of Stable Protein Formulations in Fine Granules"
`
`Alza, 1999-2000, $50,000
`
`Co-PI's: Dr. Robert Sievers and John Carpenter
`
`"Production of Fine Powders of Protein Formulations with Super Critical Carbon
`
`Dioxide Assisted Spray-Drying"
`
`Aviron, 2000-2001, $112,000
`
`Co-PI's: John Carpenter, Robert Seivers and Ted Randolph
`" Preparation of Stable Dry Powder Formulations of Live Attenuated Virus Vaccines"
`
`Iomai, 2000-2001, $85,000
`
`Co-PI's: John Carpenter, Ted Randolph, Mark Manning and Mark Duncan
`" Development of Stable Formulations of Antigen and Protein Adjuvant for Patch
`Transdermal Delivery Systems"
`
`Colorado Ins