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`NEWS TOPICS ANALYSIS FEATURES LIBRARY EVENTS JOBS MARKETPLACE
`
`Topics: Sales and Marketing
`The top 10 bestselling multiple sclerosis drugs
`of 2013
`September 9, 2014
`
`SHARE
`
`Want a surefire way to shake up a drug market? Introduce new
`medication options that make it easier for patients to manage
`their disease. MS drugmakers would know; their market is all of a
`sudden full of them.
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`For one, a gamechanging trio of pills is providing an alternative
`to injections. Novartis' ($NVS) Gilenya hit first in September
`2010, followed by Sanofi's ($SNY) Aubagio and Biogen Idec's
`($BIIB) Tecfidera. Two of those three, Gilenya and Tecfidera, nabbed spots on
`our list of Top 15 drug launch superstars after hitting the ground running. They're
`primed to keep moving up the food chain, too.
`
`Then, there are new, longacting meds like the 40mg version of bestseller
`Copaxone, which hit the market just in time for maker Teva ($TEVA) to start
`converting patients ahead of a bumpedup May patent expiration. With a
`Supreme Court appeal in its patent case set to begin soon, Teva's seeing
`patients switch over to the new formulainjected thrice weekly, as opposed to
`dailyat a rate that has so far both surprised and impressed analysts. Biogen
`Idec, too, recently snagged the FDA's favor for its own longlasting med, a
`followup to Avonexdubbed Plegridythat requires injection only once every
`two weeks.
`
`Drugmakers are looking for more subtle yet significant ways to make their MS
`meds more attractive to patients, too. Take Biogen's Avonex Pen, for instance,
`greenlighted by the FDA the year before last. The Massachusetts biotech billed
`it as the first "intramuscular autoinjector" approved for MS and one it hoped
`would reduce "injection anxiety" and "pain."
`
`All of these factors are helping
`redraw the MS treatment map, and
`we could soon be looking at a new
`king on the MS throne. So quick
`check out our review of how the top
`10 products stacked up in 2013,
`based on data from
`
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`5/27/2015
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`The top 10 best-selling multiple sclerosis drugs of 2013 - FiercePharma
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`http://www.fiercepharma.com/special-reports/top-10-best-selling-multiple-sclerosis-drugs-2013
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`MYLAN PHARMS. INC. EXHIBIT 1115 PAGE 1
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`
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`EvaluatePharma. The bestsellers
`list will look different before you know it. Carly Helfand (email | Twitter) and
`Eric Palmer (email | Twitter)
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`1
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`2
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`3
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`4
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`5
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`Copaxone
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`Avonex
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`Rebif
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`Gilenya
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`Tysabri
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`6
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`7
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`8
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`9
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`Betaseron/Betaferon
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`Tecfidera
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`Ampyra
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`H.P. Acthar Gel
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`10 Aubagio
`
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`Interest in using electronic patient
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`Cantrell and Becky Baggett will share lessons
`learned working on a large phase 3 pain study
`that utilizes ePRO on tablet devices. Register
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`Filed Under multiple sclerosis
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`COMMENTS
`9 Comments
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`Leslye Gower • 9 months ago
`Huh. What poison will they think of next?
`
`• Reply •
`Share ›
` 1
`
`
`Lynne Heal
` • a month ago
`> Leslye Gower
`One MS drug even had furniture polish added to it
`
`• Reply •
`Share ›
`
`
`Lynne Heal • 6 months ago
`Many MS drugs are deadly they all need to be scrutinised along with everyone whos
`promoted them. This is also why a cure for MS will never be found because too
`many have made trillions from MS drugs all having profits , shares and
`commmissions alongside very high salarys its so easy to work out whats going on
`in MS http://www.newsmax.com/Health/... http://www.independent.co.uk/l...
`
`• Reply •
`Share ›
`
`
`The Dame Judy Dench
` • 4 months ago
`> Lynne Heal
`what treatment do you suggest we take?
`
`• Reply •
`Share ›
`
`
`Lynne Heal
` • 4 months ago
`> The Dame Judy Dench
`CCSVI is whats needed it works and is NOT deadly at all here is
`atlast someone being sued for naysaying CCSVI and knows many
`more will be too http://news.nationalpost.com/n...
`
`• Reply •
`Share ›
`
`
`Bill Anderson
` • a month ago
`> Lynne Heal
`CCSVI has been deadly, not to mention that it doesnt work
`
`• Reply •
`Share ›
`
`
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`Lynne Heal
` • a month ago
`> Bill Anderson
`MS drugs are MORE deadly http://www.family-
`announcement...
`• Reply •
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`Share ›
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`5/27/2015
`
`The top 10 best-selling multiple sclerosis drugs of 2013 - FiercePharma
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`http://www.fiercepharma.com/special-reports/top-10-best-selling-multiple-sclerosis-drugs-2013
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`MYLAN PHARMS. INC. EXHIBIT 1115 PAGE 2
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`painkills2 • 9 months ago
`In 2014, will the list include Sativex?
`
`• Reply •
`Share ›
`
`
`Lynne Heal
` • 4 months ago
`> painkills2
`Sativex is not like MS drugs this drug helps the pain yet denied. Its so easy
`to work out whats really going on in MS
`
`• Reply •
`Share ›
` 1
`
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`5/27/2015
`
`The top 10 best-selling multiple sclerosis drugs of 2013 - FiercePharma
`
`http://www.fiercepharma.com/special-reports/top-10-best-selling-multiple-sclerosis-drugs-2013
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`MYLAN PHARMS. INC. EXHIBIT 1115 PAGE 3
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`5/27/2015
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`The top 10 best-selling multiple sclerosis drugs of 2013 - FiercePharma
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`http://www.fiercepharma.com/special-reports/top-10-best-selling-multiple-sclerosis-drugs-2013
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`MYLAN PHARMS. INC. EXHIBIT 1115 PAGE 4