(19) Japan Patent Office (JP)
`(12) Patent Gazette (A)
`(11) Japanese Patent Application Publication
`Number HEI 8 — 231391
`
`(51) Int. Cl 4 Classification Symbol Internal No.
`A23L 1/42
`8412—4B
`
`A61 K 9/48
`
`31/355
`
`ADL
`
`6742—4C
`
`7330—4C
`
`(43) Publication Date August 13, 1985
`
`(54) Title of Invention
`
`(72) Inventor
`(72) Inventor
`(71) Applicant
`
`Request for Review Unrequested Number of Claims 1 (Total 2 Pages)
`
`Nutritional Supplement
`(21) Application Number
`Sho 59 — 10625
`(22) Application Date
`January 24, 1984
`Motuski Kenji
`Tokyo-to, Nakano-ku, UenoMiya 4 Choume 9 Ban 6 Go
`Fukuoka Ryuu
`Tama-shi Nagayama 4 No 4 No 21 No 304
`Honen Seiyu Co. Ltd.
`Tokyo-to, Chiyoda-ku, Otemachi 1 Choume 2 Ban 3 Go
`
`Specification
`1. Title of Invention
`
`Nutritional supplement
`2. Scope of Claims
`(1) A nutritional supplement being contained inside
`a gelatin capsule and comprising a nutritional liquid
`being formed by melting vitamin E, soybean
`lecithin in an oil having high eicosapentaenoic acid
`content.
`
`(2) A nutritional supplement of claim 1 wherein the
`oil having high eicosapentaenoic acid content is a
`sea animal oil such as pilchard oil, mackerel oil,
`cuttlefish oil, krill oil, or mink oil.
`3. Detailed Explanation of the Invention
`The present invention relates to a new nutritional
`supplement having as its primary ingredients
`vitamin E, soybean lecithin, and an oil having high
`eicosapentaenoic acid content. In recent years, the
`demand for nutritional supplements has greatly
`increased due to factors such as (1) lack of
`nutritional balance brought about by a rich food
`culture, (2) pickiness and lack of food diversity
`caused by a selective food palette, (3) lack of
`nutrition brought about by a breakdown in balance
`of nutrition and health, exercise, and energy, and (4)
`the necessity for supplementary nutrition to
`correspond to an aging population. In particular, the
`desire to stem adult disease by the improvement of
`food life is strong, so people enjoy eating nutritional
`supplements.
`
`The present invention arises out of the
`aforementioned nutritional needs and its object is to
`provide a new nutritional supplement from the
`combination of vitamin E, which (1) prevents the
`aging of cells, (2) lowers cholesterol and prevents
`the hardening of arteries, (3) prevents the
`occurrence of liquid fatty deposits and encourages
`cell life, (4) cleans and washes blood vessels and
`prevents brain or heart blood clots; soybean lecithin,
`which (1) encourages the absorption of vitamin E
`and eicosapentaenoic acid, (2) reduces cholesterol
`and prevents hardening of blood vessels and oil
`having high eicosapentaenoic acid content, which is
`effective anti-platelet aggregation, making it an
`anti-coagulant and acts to prevent the hardening of
`blood vessels.
`
`In other words, the present invention is a
`nutritional supplement consisting of vitamin E and
`soybean lecithin melted in an oil having high
`eicosapentaenoic acid content in liquid form
`inserted into a gelatin capsule.
`
`As for the vitamin E used in the present invention,
`items obtained by publicly known methods such as
`concentration by chromatography or molecular
`distillation of plant oils are appropriate, but the
`method of production thereof is not limited, and the
`source of energy is also not limited.
`Vitamin E is included in great amounts in
`safflower oil, rice oil, corn oil, and other oil from
`water dwelling plants. However, the concentration
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`Petition for Inter Partes Review
`Of U.S. Patent 8,278,351
`Exhibit
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`ENZYMOTEC - 1014
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`AKER877|TC00804540
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`of the oil is at most 0.3%, so using any of these as-is is not desirable.
`
`Also, soybean fatty substance containing soybean oil obtained by
`dehydrating and drying gum produced by the production of soybean
`gum is generally acceptable for the soybean lecithin used in
`conjunction with vitamin E, but it is also acceptable to use lecithin
`that has been sugared and concentrated via acetone or alcohol, and it
`is also possible to use separated lecithin that contains little of no
`keratin.
`
`effects will not be sufficient. A nutritional supplement
`formed by melting vitamin E and soybean lecithin in oil
`The amount of vitamin E included in the present invention must be at with a high concentration of eicosapentaenoic acid, within
`least 1% of the liquid included in the capsule. If less than this
`the scope wherein it is possible to maintain the relative
`concentration is achieved the activity of the vitamin in the body is
`levels of the various substances, may be diluted with
`reduced, and the benefits of vitamin E cannot be achieved.
`safflower oil, rice oil, corn oil, soybean oil, or seaweed oil
`or other sea life oil. Mixed oil obtained in this way is
`inserted into a gelatin capsule under normal circumstances.
`As one example of the method of sealing the substance in
`a capsule, the mixed liquid will be sealed in a gelatin
`capsule in a certain amount, the gelatin formed by melting
`gelatin, glycerin, and water. After that, the entry hole will
`be heated and sealed to create the nutritional substance of
`the present invention.
`The form of the gelatin capsules may be spherical or in
`the form of a rugby ball.
`This soybean lecithin must be present in the liquid that is inserted
`Because the nutritional supplement of the present
`into the capsule in a concentration of at least 1%. As noted before, if
`invention obtained in this way contains vitamin E which
`the concentration falls below this level the effects of the substance
`prevents the aging of cells, lowers cholesterol numbers,
`will not be sufficient. In addition, for oil with a high concentration of
`prevents excess fat deposits, and has other positive side
`eicosapentaenoic acid (C20 : 5) that has vitamin E and soybean
`effects, as well as contains soybean lecithin, which acts to
`lecithin dissolved within it, an oil with a eicosapentaenoic acid
`lower cholesterol and promote the absorption of
`content of 8% or higher may be used, such as that found in sea
`eicosapentaenoic acid, and contains eicosapentaenoic acid,
`animal oils such as pilchard oil, mackerel oil, cuttlefish oil, krill oil,
`or mink oil, or an oil that was derived from one of the above and had which acts to prevent the hardening of blood vessels, the
`was concentrated with respect to eicosapentaenoic acid content.
`combined effects of the various ingredients act to reduce
`the cholesterol levels in the blood, prevent high blood
`pressure, reduce fat, and promote heart and brain function
`in brain and heart medical patients, and acts to treat and
`prevent adult circulatory diseases, and as such can be said
`to function as a nutritional supplement.
`
`The concentration of oil having a high concentration of
`eicosapentaenoic acid in the present invention must be at least 10%
`of the volume of liquid in the capsule. If this concentration is not
`achieved then the effect of the oil in the body will be lacking and as
`noted before the
`
`Below, the embodiments of the present invention are explained.
`Embodiment 1.
`
`25 parts vitamin E and 25 parts soybean lecithin are dissolved into
`50 parts fish oil (containing 16% eicosapentaenoic acid), heated to
`around 60 degrees Celsius, and dried.
`Then 60 parts gelatin, 30 parts glycerin, and 10 parts water are
`uniformly mixed, are made to take a film like form, are poured into a
`300 milligram capsule and put into a gelatin container. The
`aforementioned compound is poured into this container, the entry
`point is heat sealed, and the nutritional supplement of the present
`invention is formed.
`
`Embodiment 2
`
`30 parts vitamin E by weight and 30 parts soybean lecithin are
`dissolved into a 1:1 mixture of safflower oil and market concentrated
`
`eicosapentaenoic acid oil (produced by Nippon Yushi Co. Ltd., Sun
`Omega, and containing 25% eicosapentaenoic acid), the mixture
`being 40 parts. The liquid is heated to around 60 degrees Celsius and
`dried.
`
`Then 60 parts gelatin, 30 parts glycerin, and 10 parts water are
`uniformly mixed, are made to take a film like form, are poured into a
`300 milligram capsule and put into a gelatin container. The
`aforementioned compound is poured into this container, the entry
`point is heat sealed, and the nutritional supplement of the present
`invention is formed.
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