`Medtronic, Inc., Medtronic Vascular, Inc.,
`& Medtronic Corevalve, LLC
`v. Troy R. Norred, M.D.
`Case IPR2014-00111
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`Ovid: Bibliographic Records
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`htlp:ligateway.ovid.comirel41Diserverliovidwebcgi
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`Mediine <1966 to July Week 4 2000>
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`Results of your search: from 4 [1 and 2 and 3] keep 1-3
`Citations available: 3
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`Citations displayed: 1-3
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`Citation 1.
`
`Unique Identifier
`98414?35
`Authors
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`Werniy JA. Crawford MH.
`Institution
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`Division of Thoracic and Cardiovascular Surgery, University of New Mexico School of Medicine. Albuquerque,
`USA.
`
`Title
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`Choosing a prosthetic heart valve. [Review] [59 refs]
`Source
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`Cardiology Clinics. 16(3):491-504, 1998 Aug.
`Abstract
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`Although most of the available prosthetic heart valves function remarkably well. the variety of available choices
`attests to the inability of any single one to fulfill the requirements of the ideal valve substitute. The mechanical
`prosthesas include the caged-ball. tilting-disc, and bileaflet valves. Tissue valves available in the United States
`are the Carpentier—Edwards and Hancock porcine heterograft valves and the Carpentier—Edwards pericardial
`valve. Review of several large comparative studies on valve performance reveals that the overall results with
`tissue and mechanical valves are about equal at the end of 10 years. The characteristics of each type of valve
`substitute dictate the selection of one prosthesis in preference to others for a particular patient. Mechanical
`prostheses are recommended for patients without contraindications for anticoagulants. Tissue valves are
`reserved for patients over 65 years of age or for patients in whom anticoagulation is contraindicated. Multiple
`other patient-related factors need to be considered in selecting the appropriate valve. including the
`psychosocial situation and patient preference. [References 59]
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`Citation 2.
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`Unique Identifier
`98339145
`Authors
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`Hirai S. Fukunaga S. Sueshiro M. Watari M. Suede T. Matsuura Y.
`Institution
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`First Department of Surgery, Hiroshima Unviersity School of Medicine. Japan.
`
`Title
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`Assessment of a new silicone tri-leaflet valve seamlessly assembled with blood chamber for a low-cost
`ventricular assist device.
`Source
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`Hiroshima Journal of Medical Sciences. 4?(2):47-55, 1998 Jun.
`Abstract
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`We have developed a practical. low-cost ventricular assist device (VAD) comprising a newly designed blood
`chamber with a silicone lenticular sac and two silicone tri-leaflet valves (SW). made en bloc. This new VAD is
`seamless. can be made cost-effectively and assembled with the blood chamber and valve as one body. This
`novel design should reduce the incident of thrombus formation because of the absence of a junction at the
`connecting ring and because of the use of flexible silicone materials which have both antithrombogenecity and
`biocompatibility. in in vitro hemodynamics testing, a batch of 3 consecutively manufactured VADs with SWS
`underwent hydrodynamic functional testing. These showed less regurgitation. a lower value of water hammer
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`NORRED EXHIBIT 2111 - Page 2
`NORRED EXHIBIT 2111 - Page 2
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