Curriculum Vitae
`
`Abdul Gaffar
`
`(Office) PharmHealth Technologies ,Inc.
`(Home) 89 Carter Rd., Princeton, NJ 08540
`Rangoon, Burma
`US. Citizen, married, one son
`
`University of Karachi
`Major: Chemistry / Bacteriologt
`Brigham Young University, Provo, UT
`Major: Bacteriology / Biochemistry
`Ohio State University, Columbus, OH
`Major: Immunochemistry / Microbiology
`
`Name:
`Address:
`
`Place of Birth:
`Personal Data:
`
`Education:
`
`BS.
`
`1963
`
`MS.
`
`1965
`
`PhD.
`
`1967
`
`Management Training:
`
`1982
`
`1987
`
`Honors:
`
`1977
`1978
`
`1982
`1984
`
`1998
`
`2000
`2005
`
`— Sloan School of Management, MIT
`Management of Research, Development and Technologi Innovation
`- Member — Strategic Management Society
`— Kepner-Tregoe - The Rational Manager (Facilitator)
`— Synectics: Arthur D. Little (Facilitator for creativity session)
`— Center of Creative Leadership
`
`Colgate-Palmolive Presidential Award for outstanding contributions to R&D
`Colgate—Palmolive Presidential Award (second time) for development of new products in
`dental areas
`
`New Product Award (Won 5 out of 10)
`Development Award for developing exceptional oral research and development team
`(highlighted in Colgate—Palmolive Company's 1984 and 1986 annual report)
`Fortune Magazine innovator for development of advanced therapeutic toothpaste
`(January 12, 1998)
`Inducted in New Jersey Inventors Hall of Fame
`Received “Heroes of Chemistry” award, American Chemical Society
`
`Professional Appointments:
`
`1968-1982
`
`1982—1986
`
`Divisional Manager, Colgate—Palmolive R&D
`- Managed research development staff for the development of new therapeutic agents;
`supported existing product lines; coordinated research, product development;
`implemented safety, toxicity and efficacy studies for phase I, II and II IND
`Director of Research, Corporate Research, Colgate-Palmolive R&,D
`- Conducted and directed worldwide research and development efforts in oral care
`category, specifically development of products for caries, periodontal disease (chronic
`inflammation of gums), mouth odor, oral ulcers, anti-tartar, etc. The total business is
`approaching one billion dollars annually worldwide.
`Key products developed include MFP toothpaste in dispenser; Peroxyl, Dentagard
`(Italy), Anti—tartar (USA and Europe)
`- Implemented outside research and development in personal care products with
`academic and non—academic centers in the US. and abroad including joint research
`programs with pharmaceutical companies
`Interfaced with regulatory agencies (FDA, etc.) and professional associations in USA
`and abroad
`
`CLIO USA
`EXHIBIT 1013
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`CLIO USA
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`EXHIBIT 1013
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`

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`1
`
`986- 1989
`
`1 98 6—present
`
`1 986—1 987
`
`1 987—1 988
`1 988—1 990
`
`l
`
`990—1992
`
`1990
`1991
`
`1992-2000
`
`1 995
`
`Worldwide Director and Distinguished Research Fellow, Colgate—Palmolive R&D
`
`Strategic Alliances
`- Academic: Established / nurtured strategic alliances with key academic centers in
`USA/abroad to develop technologies in the area of chronic inflammation control, bone
`diseases, natural antibacterials, bioreactor enzymes. Managed R&D budget of $10MM
`- Industries: Set up technology acquisition / alliances with pharmaceutical / chemical
`companies and centers of excellence worldwide. At least 10 successful alliances were
`established
`
`— Developed / implemented superior technology for tartar control, yielding worldwide sale
`of $200MM. Unique feature was that not only was the technology developed, but
`commercialized in 31 countries in 1.5 years
`- Developed Colgate Tartar Control Rinse, yielding annual sale of $25MM in USA
`- Developed technologies for controlling gum diseases sold under Colgate Gum
`Protection and AntiBrush worldwide, currently in 22 countries yielding $50MM
`business
`
`
`Worldwide Director Advanced Technology-Oral Care, Colgate-Palmolive Technology
`Center
`
`— Colgate Total dentifrice technology — worldwide sales of $1 billion
`— Professional whitening system (Colgate Platinum)
`
`Vice President, Advanced Technology—Oral Care, Colgate-Palmolive Technology Center
`— Blend of technology business and broad experience in developing, nurturing and
`commercializing technologies
`- Neutralize breath control product — $10 million
`
`2000—2006(Retired)
`Center
`
`Vice President, Growth Technology Development, Colgate—Palmolive Technology
`
`— Particular expertise in new product technologies development and planning, directing,
`early commercial implementation and setting up strategic alliances with
`academia/ industries for new technology acquisitions
`- Simply White toothpaste
`— Colgate MaxFresh’
`2006(retired from Colagte)
`2006-present:CEO, PharmHealth Technologies inc
`
`2000
`2004
`
`Membership in Professional Organizations:
`
`American Association for the Advancement of Science
`American Chemical Society
`New York Academy of Sciences
`International Association for Dental Research
`Advisory Group NIDR (1978)
`International Conference on Oral Biology (member of Advisory Committee, 1995)
`Industrial Research Institute (Board of Directors 2002—2004)
`
`International Symposia Organized/ Participated:
`
`l.
`
`2.
`3.
`
`0.01
`
`7.
`
`.090
`
`Teeth / Bacteria Interaction — Therapeutic Strategy.
`Forsyth Dental Center, February 1982.
`Inter—Oral Topical Drug Delivery Systems, Colgate Symposium, October 1983.
`A Symposium on Calculus Formation and Prevention - Comp. Con. Education, University of
`Pennsylvania, September 1987.
`Recent Advances in Calculus Research, Council of Europe Symposium, IRL Press (published),
`November 6-9, 1988.
`Triclosan/Copolymer Dentifrices in the Control of Plaque /Gingivitis FDI Symposium, September 1989
`Recent Advances in Dentifrices and Mouthrinse Technology in the Prevention of Oral Diseases, FDI
`Symposium 1990. Published Am J Dent, Vol. 3, September 1990, PSl-S72.
`Recent Advances in the Diagnosis and Treatment of Periodontal Disease. Symposium International
`Academy Periodontology, Istanbul, Turkey, September 1990.
`Council of Europe Conference on Clinical and Biological Aspects of Dentifrices, Toledo, Spain, 1990
`Recent Advances in Therapeutic Rinse, FDI Symposium, Milan, 1991.
`
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`18.
`19.
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`20.
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`21.
`22.
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`23.
`24.
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`25.
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`26.
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`27.
`28.
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`29.
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`30.
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`31.
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`32.
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`33.
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`34.
`35.
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`Mini—Symposium: The Role of Tartar Control Dentifrices in Preventive Dentistry, International
`Symposium, University of Gothenburg, Sweden, September 5-6, 1991.
`Recent Advances in Calcium Phosphate /Fluoride Technology for Caries Prevention, FDI
`Symposium, Berlin, 1992.
`New Technology Regarding Triclosan/ Copolymer Dentifrices and Their Effect on Oral Health,
`Gothenburg, Sweden 1993.
`Controlled Drug Delivery: Applications in Oral Disease Therapy - Controlling Bacterial Growth and
`Inhibition, the 72nd IADR, Seattle, Washington 1994
`Interactions Between Dental Materials, Dental Tissues and Oral Fluids, Leidscherdam, Neth.
`of Europe Meeting), October 27-30, 1994
`Recent Advances in Calculus Control, FDI Meeting, Vancouver, Canada, 1994
`Frontiers in Dental Therapeutics, FDI Meeting, FDI Meeting, Hong Kong, October 1995
`Dental Caries: New Frontiers and Prospects, FDI Meeting, Hong Kong, October 1995
`Advances Cosmetic Sciences and Technology, ASEAN COFA, Bangkok, Thailand, October 1995.
`Plaque Dynamics at the Tooth /Gingival Frontier: Chemical Agents for the Control of Plaque. FDI
`Meeting. Orlando, Florida. 1996.
`Dental Research Crossing the Millennium (symposium in honor of Gunnar Rolla, University of
`Oslo). Oslo, Norway. April 1997.
`Fluoride Varnish in Current Dental Practice. ADA Meeting. Washington DC. 1997.
`Dentinal Hypersensitivity: Cause and Prevention. ADA Symposium 138th Meeting. Washington
`DC 1997.
`
`(Council
`
`Recent Advances in Plaque / Gingivitis / Tartar/Caries. Seminars at USC, UCLA, UCSF. 1997.
`Recent Advances in Therapeutic and Whitening Toothpaste Technologies. APDC, Bangkok,
`Thailand. January 1998.
`Recent Advances in Therapeutics for Plaque, Calculus, Gingivitis, and Caries. Seminar at
`University of Seattle. January 1998.
`Enamel Fluorosis and Dose Response of Fluoride for Anti—Caries Effect. Fluoride Symposium,
`Boston. March 1998.
`
`Triclosan Symposium. Frankfurt, Germany. April 1998.
`The Scientific Rationale for Use of Topical Chemotherapeutic Agents for Subgingival Cloinical
`Efficacy. FDI Symposium, Barcelona, Spain. October 1998.
`Role of Saliva in Maintaining Mineral Dynamics. Saliva Symposium, Beijing, China. October
`1998.
`
`Recent Advances in Therapeutics in Plaque, Gingivitis, Calculus, and Caries Control. ADA
`Symposium, San Francisco, CA. October 1998.
`Recent Advances in Therapeutics for Plaque, Gingivitis, Calculus, and Caries Control. Chicago
`Midwinter Conference, Chicago, IL. February 1999.
`Dental Therapeutics — Current Status and Future Prospects. Hubei University, China. October
`1999.
`
`Tooth Whitening — Present Status and Future Prospects. Lorna Linda University. November
`1999.
`
`Recent Advances in Dental Therapeutics. NYU Dental School. February 2002.
`Recent Advances in Tooth Whitening Technology. FDI Meeting, Sydney, Australia. September
`2003.
`
`Bibliography:
`
`Original Papers
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`1.
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`2.
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`3.
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`7.
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`Filament Formation in Clostridium acidi urici under Conditions of Elevated Temperatures. Terry,
`D. R., Gaffar, A., and RD. Sagers. J. Bact. fizl625-1634 (1966).
`Amino Acid Composition of Walls from Single and Filamentous Cells of Clostridium acid urici.
`Gaffar, A., Terry, D. R. and RD. Sagers. J. Bact. flzl6l8-1623 (1966).
`Serologica Analysis of Nuclear Antigens from Normal and Malignant Human Tissues. Gaffar, A.,
`Bigley, N. J., and M.C. Dodd. Federation Proc. @12) (1967).
`Sequence of Immunoglobulin Production in Rabbits. Gaafar, H. A., Gaffar, A., and M.C. Dodd.
`68th Annual Meeting of ASM, Detroit, Michigan. Bact. Proc. page 69 (1968).
`Role of Microorganisms in the Antigenicity of Human Gingival. Ferris, R. T., Gaafar, H., Gaffar,
`A., and M.C. Dodd. Bact. Proc. page 70 (1968).
`Effect of Reticulo—Endothelial System Blockade on the Antigenicity of IgM Coated Sheep Red
`Blood Cells. Klun, C., Gaafar, H., Gaffar, A., and M.C. Dodd. Bact. Proc. page 74 (1968).
`Studies on a Human Lung Rabbit Anti—Lung Complex Formed in vivo. Gaafar, H., Gaffar, A.,
`Ferris, R. T. and M.C. Dodd. Proc. VI Intern'l Allergol., Montreal (1967).
`
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`Immunochemical Properties of Nucleoprotein Antigens from Normal and Malignant Human
`Tissues. Gaffar, A. Dissertation Abs. 2819), 3799—B (1968).
`Immunological Properties of Human Gingival Tissues. Ferris, R. T., Gaffar, A., Gaafar, H., and
`Dodd, M. C., International Association for Dental Research (IADR), page 409, 46th General
`Meeting, San Francisco (1968).
`Effects of Inoculation in a Levan Forming Cariogenic Streptococcus on Experimental Caries in
`Hamsters. Gaffar, A. and E.J. Coleman. Arch. Oral Biol. 521393 (1970).
`The Influence of Inoculation of Human Cariogenic Bacteria Upon Periodontal Bone Resorption in
`Golden Hamsters. Gaffar, A. and E.J. Coleman. Arch. Oral Biol. 521371 (1971).
`Effects of Specific Immunization on Experimental Dental Caries in Hamsters. Gaffar, A.,
`Marcussen, H.W. and RC. Kestenbaum.
`IADR Abstracts, page 124, 48th General Meeting, New
`York (1970).
`Mast Cells and Periodontal Disease. Coleman, E. C. and A. Gaffar. J. Periodont. Res. 2:366
`(1975).
`Microbiological Aspects of a Hamster Caries Infection Model. Schlissel, H. H., Ruffner, J. and A.
`Gaffar.
`IADR Abstracts, Chicago, #348, p. 139 (1971).
`Effects of Specific Immunization with an Enzyme on Experimental Dental Caries in Hamsters.
`Gaffar, A., Marcussen, H. W., Schlissel, H. J. and AR. Volpe.
`IADR Abstracts, Chicago, #349, p.
`140 (1971).
`Effects of Topically Applied Streptococcal Extracellular Polysaccharide on Rat Gingiva. Gaffar, A.,
`Marcussen, H. W. and E.J. Coleman.
`IADR Abstracts, Las Vegas (1972).
`Effects of Chlorhexidine Dihydrochloride in the Diet on Caries in Hamsters. Gaffar, A.,
`Marcussen, H.W. and RC. Kestenbaum.
`IADR Abstracts, 1973; J. Dent. Res. 2:143 (1973).
`Distribution of Streptococcus mutans and Streptoccus sang1_.1is in Plaque from Caries Resistant
`and Caries Active Subjects. Gaffar, A., Vida, J. and I. Mandel. J. Dent. Res. Special Issue
`2:459 (1973).
`Effects of Sequential Treatments with Streptococcal Hyaluronidase and Polysaccharide on Rat
`Gingiva. Gaffar A. and E.J. Coleman. J. Dent. Res. Special Issue @2323 (1974).
`Determination of Cystein Desulfydrase Activity in the Incubated Saliva. Solis—Gaffar, M. C. and
`A. Gaffar. J. Dent. Res. Special Issue 54:60 (1975).
`Longterm Antiplaque Effects of Benzethonium Chloride in Beagle Dogs. Gaffar, A., Rustogi, K.
`and MC. Gaffar. J. Dent. Res. (Special Issue) 57:486 (1978).
`Effects of Specific Immunization on Dental Caries in Hamsters. Gaffar, A. J. Dent. Res. 5_5:C22 1
`(1976).
`Longterm Antiplaque Effects of Benzethonium/Polymer Complex in Beagle Dogs. Gaffar, A.,
`Tavss, E. and K. Rustogi. J. Dent. Res. (Special Issue) £2486 (1978).
`Instrumental Evaluation of Odor Produced by Specific Oral Microorganisms. Solis—Gaffar, M. C.,
`Fischer, T. and A. Gaffar. J. Dent. Res. _5_Z (Special Issue): 803 (1978).
`Longterm Antiplaque Effects of Benzethonium Chloride in Beagle Dogs. Gaffar, A., Rustogi, K.,
`Marcussen, H.W. and H. Niles. J. Periodont. Res. 1_5_:107—110 (1979).
`Penetration of Dental Plaque Components into Gingiva: Sequential Topical Treatments with
`Hyaluronidase and Streptococcal Polysaccharide in Rats. Gaffar, A. et al. J. Periodont. Res.
`_5_2:197—205 (1981).
`Effects of an Anti-Inflammatory Drug Palosein on Gingivitis in Beagles. Gaffar, A. and W.L. King.
`J. Dent. Res. 1910-11 (1978).
`Effects of Chlorhexidine Dihydrochloride in Diet on Caries in Hamsters. Gaffar, A. and H.W.
`Marcussen. Caries Res. 14:84-89, (1980).
`Studies on Antibacterially Induced Dental Staining, Gaffar, A., Landkl, D. and T. Donohue. J.
`Dent. Res. 5_8 (Special Issue): 467 (1979).
`Instrumental Evaluation of Odor Produced by Specific Oral Microorganisms. Gaffar, M.C.,
`Fischer, LT. and A. Gaffar. J. Soc. Cosmet. Chem. @2241-247 (1979).
`Longterm Antiplaque, Anticalculus, and Antigingivitis Effects of Benzethonium Chloride /Polymer
`Complex in Beagle Dogs. Gaffar, A., Gaffar, M.C., Tavss, E., Marcussen, H.W. and K. Rustogi. J.
`Dent. Res. @: 1878—1983 (1981).
`Evaluation of an Oligomer or an Oligorner plus Cetyl Pyrodinium Chloride Against Plaque, Stain,
`Calculus and Gingivitis. Gaffar, A., Niles, HP and CB. Davis. J. Dent. Res. @1432-1439
`(1981).
`Evaluation of Editempa Against Calculus Formation In Vitro and In Vivo. Gaffar, A., Moreno,
`E.J. and H. Muhlenram. J. Dent. Res. Q: 393 (1981).
`In Vitro Evaluation of Editempa on Hydroxyapatite Formation and its Effects on Dental Enamel.
`Gaffar, A. and EC. Moreno. Calcified Tissue Int. m: 34—38 (1982).
`A Method for Studying Adsorption of Actinomyces Species to Tooth-like Substance. Gaffar, A. J.
`Dent. Res. $2310 (1982).
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`Evaluation of a Complement Inhibitor in the Experimental Gingivitis in Beagle Dogs. Gaffar, A.,
`Ren, P. and E.J. Coleman. J. Dent. Res. @310 (1982).
`In Vivo Ca45 Uptake from Dical Toothpaste by Rat Enamel. Gaffar, A. and N. Fine. J. Dent. Res.
`@223 (1983).
`Effects of Editempa on Dental Calculus and Caries Formation In Vivo,_ Gaffar, A., Moreno, EC.
`and H. Muhlenram. Calcif. Tissue Int. @2362-365 (1983).
`Studies on the Formation of Electrostatic Complexes Between Benzethonium Chloride and
`Anionic Polymers. Tavss, E., Gaffar, A. and W.L. King. J. Pharm. Sci. E:1148—1152 (1984).
`A Non—Antibacterial Approach to Reduce Colonization of Plaque Microflora to Teeth In Vitro and
`In Vivo. Gaffar, A., Esposito, A. and RT. Gibbons. J. Pharm. Sci. 7_4:1228—1272 (1985).
`Effects of Sodium Phytate and Benzethonium Chloride Rinses on Plaque Formation in Humans.
`Gaffar, A. and K. Rustogi. Caries Res. l_6_:472—479 (1982).
`The Role of Industrial Research in Developing Preventive Agents for Periodontal Diseases and
`their Implications in the Latin American Health Program. Gaffar, A. WHO Workshop, University
`of Panama, Panama (April 1984).
`Evaluation of PBTA as a Crystal Growth Inhibitor in Vitro and in vivo, Gaffar, A. and E. C.
`Moreno. J. Dent. Res. Q: 320 (1984).
`Detection of Non-Leukotoxin AA in the Oral Cavity of Mice. Coleman, E.J. and A. Gaffar,
`Hammond and Stevens. J. Dent. Res., @2320 (1984).
`Adsorption and Crystal Growth Inhibition of Hydroxyapatite by N, N, N1, Nl-ethylene Diamine
`Tetramethyline Phosphonate Editempa. Moreno, EC. and A. Gaffar. J. Dent. Res. 6_4, Sp. Issue:
`301 (1985).
`Influence of Plaque on MFP Uptake in Lesions In Vivo. Ogaard, B., Gaffar, A. and M. Bahn. J.
`Dent. Res. Sp. Issues p. 347 #1551 (1985).
`Effects of Complement Activation Inhibitor on Gingivitis Formation in Beagles. Gaffar, A., Ren, P.
`and E.J. Coleman. J. Dent. Res. Sp. Issue p. 361 #1676 (1985).
`Cariostatic Effects of Monofluorophosphate (MFP) in Solutions and Dentifrices in Rats. Schmidt,
`R., Afflitto, J. and A. Gaffar. J. Dent. Res. Sp. Issue p. 364, #1707 (1985).
`Fluoride Retention in Clean and Plaque Covered Demineralized Enamel In Vivo After Applications
`of Monofluorophosphate. Ogaard, B. and A. Gaffar et a1. Scand. J. Dent. Res. 932466—93 (1985).
`Effects of a Specific Antibacterial Therapy on Plaque /Gingivitis in Beagles. Gaffar, A., Coleman,
`E.J. and J. Afflitto. J. Dent. Res. 6_5:247 (1986).
`In Vitro and In Vivo Evaluation of Dental Mineralization Solution. Gaffar, A., Coleman, E.J. and
`EC. Moreno. J. Dent. Res. @5293 (1986).
`Relationship Between Sensory and Instrumental Evaluation of Mouth Odor. Niles, HP. and A.
`Gaffar. J. Dent. Res. 65:311 (1986).
`Calculus Revisited - A Review. Mandel, I. and A. Gaffar. J. Clinical Periodont. _1_3:247—257
`(1986).
`Interactions of Perfluoroalkyl Surfactants to Teeth In Vitro and In Vivo. Gaffar, A., Esposito, A.,
`Bahn, M. Sternberg, L. and I. Mandel. Colloids and Surfaces 26:109-121 (1987).
`In Vitro Evaluation of pyrophosphates/copolymers/NaF as an Anticalculus Agent. Gaffar, A.,
`Afflitto, J. and T. Polefka. Comp. Con. Educ. Supp. g5242—5250. 1987.
`Effects of Pyrophosphate/Copolymer/NaF on Dental Calculus and Caries Formation In Vivo.
`Gaffar, A., Afflitto, J. and T. Polefka. Comp. Con. Educ. Suppl. 8:5251-5255 (1987).
`Pre—Clinical Studies on Anticalculus Toothpaste. Gaffar, A., Moreno, EC. and J. Afflitto. J. Dent.
`Res. @258 (1989).
`Adsorption and Crystal Growth Inhibition of Hydroxyapatite (HA) by Tetrapotassium
`Pyrophosphate. Moreno, E.C., Aoba, T. and A. Gaffar. J. Dent. Res. @2123 (1988).
`Activation Lactoperoxidase and Mycloperoxidase Antibacterial System. Nabi, N. and A. Gaffar. J.
`Dent. Res. @151 (1988).
`Inactivation of Bacterial Endotoxins by PDP. Coleman, E.J. and A. Gaffar. J. Dent. Res. £2296
`(1988)
`Effects of Tetrapotassium Pyrophosphate (KPDP) on Plaque / Gingivitis I_n fl]; Gaffar, A. and J.
`Afflitto. J. Dent. Res. @2403 (1988).
`Non-Bactericidal Approach to Prevent Plaque Formation. Gaffar, A., Esposito, A. and TR.
`Gibbons. J. Dent. Res. 6_7_:403 (1988).
`Efficacy of Ibuprofen in Rinse in a Subgingival Irrigation System. Gaffar, A., Coleman, E.J. and
`L. Steinberg. J. Dent. Res. @830 (1989).
`Preparation of Phosphorus 33Labelled Potassium Peroxydiphosphate, K4P208. Fine, N. and A.
`Gaffar. J. Labelled Comp. 2_7, #4, p. 435-438.
`Cariostatic Effects of MFP in Solution and Dentifrices in Rats. Schmid, R., Afflitto, J. and A.
`Gaffar. J. Clin. Dent. 1:75-82 (1989).
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`In Vitro and In Vivo Studies on Triclosan/ PVM/ MA Copolymer/ NaF Combination as an
`Antiplaque Agent. Gaffar, A., Nabi, N., Herles, S. and J. Afflitto. Am. J. Dent. 2:197—206 (1989).
`Salivary and Plaque Triclosan Levels after Brushing with 0.3% Triclosan/ Copolymer/ NaF
`Dentifrice. Afflitto, J., Smith, S. and A. Gaffar. Am. J. Dent. 3:207-210 (1989).
`A Non-Antibacterial Approach to Prevent Plaque Formation. Giersten, E. and A. Gaffar. J. Dent.
`Res. @21673-1685 (1989).
`Physical Chemistry of Calculus Formation. Moreno, E. C., Aoba, T. and A. Gaffar. Recent
`Advances in Cal. Res. IRL Press, pp. 129-142 (1989).
`Structure / Activity Relationship Between In Vitro Inhibition of HA Crystal Growth and In Vivo
`Anticalculus Effect. Gaffar, A., Aoba, T., Afflitto, J. and EC. Moreno. Recent Advances in
`Calculus Research, IRL Press, p. 1255-173 (1989).
`113Cd NMR Study of the Inhibitory Effects of PVM/MA Copolymer on Alkaline Phosphatase of E.
`Coli. Afflitto, J., Smith, K. A. and A. Gaffar. J. Dent. Res. @118 (1990).
`Anticalculus Effects of Soluble Pyrophosphate Dentifrices with or without Copolymer. Singh, S.,
`Rustogi, K. and A. Gaffar. J. Dent. Res. @2251 (1990).
`Cariostatic Effects of PDP and PDP Plus Fluoride. Gaffar, A. and A. Esposito. J. Dent. Res.
`@2373 (1990).
`A Comparative Anticalculus Effect of Dentifrices Containing 1.3% Soluble Pyrophosphate With or
`Without Copolymer. Schiff, T., Volpe, A R. and A. Gaffar. J. Clin. Dent. 2 #2 (1990).
`Antiplaque Effects of Dentifrices Containing Triclosan/
`Copolymer/NaF System vs. Triclosan Dentifrices without the Copolymer. Gaffar, A., Nabi, N.,
`Kashuba, B., Williams, M., Herles, 8., Olsen, S. and J. Afflitto. Am. J. Dent. 3:507—514 (1990).
`In Vitro and In Vivo Anticalculus Effects of a Triclosan/ Copolymer System. Gaffar, A., Esposito,
`A. and J. Afflitto. Am. J. Dent. $537.
`In Vitro Antiplaque Effects of a Triclosan/ Copolymer Mouthrinses. Williams, M., Herles, S.,
`Afflitto, J. and A. Gaffar. Am. J. Dent. 3:353—356 (1990).
`Recent Advances in Plaque / Gingivitis Control. Gaffar, A., Volpe, A. R. and J. Lindhe. Council of
`Europe Meeting on Biological and Clinical Aspects of Dentifrices, Toledo, Spain (November 1990).
`Effects of Potassium Peroxydiphosphate on Bone Resorption. Gaffar, A., Alander, C. B. and L.G.
`Raisz. J. Bone Min. 621037-1041 (1991).
`Cd NMR Studies of Inhibitory Effect of PVM / MA Copolymer on Alkaline Phosphatase Activity.
`Afflitto, J., Paul, M. and A. Gaffar. Pharm. Res. 8211 (1991).
`Chemical Tartar Control Technology. Gaffar, A. Cosmetic & Toiletries flz73-77 (1992).
`Fluoride Availability in Human Saliva after Dentifrice Use: Correlation with Anticaries Effects in
`Rats. Afflitto, J. and A. Gaffar. J. Dent. Res. 11:841—845 (1992).
`Chemotherapeutic Mouthrinses for the Control of Oral Disease. Gaffar, A. and J. Afflitto.
`International Dental Journal, QM): 253—262 (1992).
`Improving Effectiveness of Fluoride: The Role of Calcium and Phosphate. Gaffar, A., Blake—
`Haskins, J. and J. Mellberg. International Dental Journal fin): 81-88 (1993).
`Influence of Anticalculus Mouthrinse Treatment on Dentifrice and Periodontium in Beagle Dogs.
`Gaffar, A., Coleman, E.J. and J. Afflitto. J. Clin. Dentistry B12—B18.
`Relationship Between Sensory and Instrumental Evaluations of
`Mouth Odor. Niles, HP. and A. Gaffar. J. Soc. Cosmetic Chemistry fl: March—April 1993.
`Evaluation of Tartar Control Dentifrices In Vitro Models of Dentin Sensitivity. Mason, S. and A.
`Gaffar. Clin. Prev. Dent. 12:42 (1990).
`A Model for Studying the Effects of Mouthrinses on De Novo Plaque Formation. Ramberg, P.,
`Furceichi, Lindhe, J. and A. Gaffar. J. Clin. Periodontol. fiz509-520 (1992).
`Controlled Drug Delivery for Periodontal Infections using Acrylic Cure Polymers — In Vitro Studies.
`Toddywala, R., Afflitto, J. and A. Gaffar. J. Pharm. Res. (in press).
`Toothpaste Technology. Gaffar, A., Nabi, N. and J. Afflitto. Chem. Tech. @238—42 (1993).
`Recent Advances in Triclosan/Copolymer/NaF Technology. FDI Symposium. Gaffar, A., Kruger,
`I., Herles, S. and J. Afflitto. International Dental Journal (in press) (1994).
`Evaluation of New Dentifrice for the Treatment of Sensitive Teeth. Miller, S. and A. Gaffar. J.
`Clin. Dent. 5 Sp Iss: 71-79 (1994).
`Absorption of Peroxydiphosphate onto Hydroxyapatite: Kinetics, Thermodynamics, and Crystal
`Growth Inhibition. Moreno, E. and A. Gaffar. J. Colloid Int. Sciences. @2173-182 (1994).
`Recent Advances in Therapeutic Dentifrices. Res. Part. de Est. e. Cir. Maxilloc. 3_4(4): 245-247
`(1993).
`Chemostat Flow Cell System: An In Vitro Model for Evaluation of Antiplaque Agents. J. Dent.
`Res. B (1994).
`Plaque and Gingivitis on Deciduous and Permament Dentition. Ramberg, P., Lindhe, J. and A.
`Gaffar. J. Clin. Periodont. Az490-496 (1994).
`
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`Effects of Triclosan on Mediators of Gingival Inflammation. Gaffar, A., Scherl, D., Afflitto, J. and
`E.J. Coleman. J. Clin. Periodontol. 2_1 (1995).
`Intra-oral Remineralization of Enamel with a MFP/DCPD and MFP/ Silica Dentifrice Using
`Surface Microhardness. J. Clin. Dent. 6:148—153 (1995).
`The Effects of Antimicrobial Rinses on De Novo Plaine Formation at Sites with Healthy and
`Inflamed Gingival. Ramberg, P. Furceichi, Volpe, T., Gaffar, A. and J. Lindhe. J. Clin.
`Periodontol. @:7-11 (1996).
`Inhibition of Formation of Calcium Phosphate Deposits on Teeth and Dental Materials: Recent
`Advances. Gaffar, A. and R.Z. LeGeros. Adv. Dent. Res. 2(4) (1995).
`Studies on Dental Stains Induced by Antibacterial Agents and Rational Approaches for Bleaching
`Dental Stains. Adv. Dent. Res. 2(4) (1995).
`Brushing with Confidence. Chemistry in Britain. Q6): 51-54, (1996).
`Advances in Mouth Odor Research. Niles, H. and A. Gaffar.
`In: Bad Breath, Research
`Perspective. Mel Rosenberg Ed. Ramot Publishing, Tel Aviv University (1995).
`Clearance of SLS from the Oral Cavity. Smith, S.F., Nathoo, S. and A. Gaffar. J. Clin.
`Periodontol. %: 213-217 (1997).
`The Effect of Bicarbonate / Fluoride Dentifrices on Human Plaque pH. Blake-Haskins, J .C.,
`Gaffar, A., and AR. Volpe. J. Clin. Dent. 8: 173—177 (1997).
`Chemical Agents for the Control of Plaque and Plaque Microflora: An Overview. Gaffar, A.,
`Afflitto, J. and N. Nabi. Eur. J. Oral Sci. fl: 502-507 (1997).
`In Vivo Detection of Calcium from DCDP in Demineralized Human Enamel and Plaque. Sullivan,
`R.J., Zhang, Y.P. and A. Gaffar. Adv. Dent. Res. _1_1(4): 380-387 (1997).
`Recent Advances in Dentifrice Technologies.
`In: Calcium Phosphates in Biological and Industrial
`Systems. Z. Amjad Ed. Kluwer Academic Publishers, Norwalk MA. pp. 325—355 (1998).
`Cariostatic Effects of Xylitol/NaF Dentifrice In Vivo. Gaffar, A., Blake-Haskins J .C. et al. Int.
`Dent. J. 48: 32—39 (1998).
`Crystal Growth of Hydroxyapatite in Vitro and Dental Calculus and Plaque Formation on Human
`Teeth in Vivo. Gaffar, A., Moreno E.C. et al.
`In: Water Soluble Polymers. Z. Amjad Ed. Plenum
`Press, New York (1998).
`Influence of OAS-100 on Mediators of Inflammation. Scherl, D.S., Afflitto, J. and A. Gaffar. J
`Clin. Periodontol. 26: 246-251 (1999).
`Treating Hypersensitivity with Fluoride Varnish. Gaffar, A. Compendium Supplement: Fluoride
`Varnish in Current Dental Practice @(1): 27-33 (1999).
`Studies with next generation of home care products for dentine hypersensitivity. Williams, M.,
`Moffat, W., Stranick, M. and A. Gaffar.
`In: Tooth Wear and Sensitivity. M. Addy Ed. Martin D.
`Dunitz, London. pp. 339-349 (2000).
`Present and future technologies of tooth Whitening. Viscio, D., Gaffar, A., Fakry—Smith, S. and T.
`Xu. Compendium of Continuing Education 21 (Sp. Suppl): 339-349 (2000).
`Oral care products.
`In: Handbook of Cosmetic Science and Technology. A.O. Barel, M. Paye and
`HI. Maibach Ed. Marcel Dekker Inc., NY. pp. 619-643 (2000).
`Recurrent oral ulcers — a review. Compendium of Continuing Education Q (Sp. Suppl.): 3-6
`(2001).
`Applications of polymers in dentifrices and mouthrinses. Gaffar, A. et al. J. Clin. Dent. Q: 138'
`148 (2002).
`Antiplaque biocides and bacterial resistance: a review. Sreenivasan, P. and A. Gaffar. J. Clin.
`Periodontol. £2 965-974 (2002).
`Effect of a triclosan—containing toothpaste supplemented with 10% xylitol on mutans Streptococci
`in saliva and dental plaque. A 6 month study. Jannesson, L., Renvert, S., Hjellsdotter, P., Gaffar,
`A. and D. Birkhed. Caries Research 36: 36-39 (2002).
`The improved remineralization and fluoride uptake in vivo of Triclosan/copolymer/ sodium
`fluoride toothpaste vs. sodium fluoride. J. Clin. Dent. _1_4_: 23-28 (2003).
`A rapid procedure to ascertain the anti-microbial efficacy of oral care formulations. Sreenivasan,
`P., Nabi. N. and A. Gaffar. Oral Microbiol. Immunol. 1_8:371-378 (2003).
`The clinical effectiveness of a dentifrice containing triclosan/copolymer for providing long—term
`control of breath odor measured chromatographically. Niles, H., Williams, M. and A. Gaffar. J.
`Clin. Dent. m (4):135—142 (2003).
`Effects of oxybenzone on PGE2 production in vitro and on plaque gingivitis in vivo. Renvert, S.,
`Birkhed, D., Scherl, D., and A. Gaffar. J. Clin. Periodontol. 3_1:91—94 (2004).
`Inflammation, periodontal diseases and systemic health. Gaffar, A., et a1. Compendium of
`Continuing Education. E #5 Suppl. 1 (2004).
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`Patents
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`Vaccines for the Prevention of Dental Caries. April 23, 1975. U.S. 3,879,545.
`Method for Local Immunization Against Dental Caries. November 23, 1976. U.S. 3,993,747.
`Method for Local Immunization Against Dental Caries. January 6, 1976. U.S. 3,931,393.
`Composition and Method of Controlling and Preventing Mouth Odor. August 9, 1977.
`U.S. 4,041,149.
`Antibacterial Composition. March 21, 1978. U.S. 4,043,679.
`Antibacterial Oral Composition. July 11, 1978. U.S. 4,100,270.
`Antibacterial Oral Composition. July 4, 1978. U.S. 4,098,880.
`Antibacterial Oral Compositions. July 25, 1978. U.S. 4,102,993.
`Antibacterial Oral Compositions. August 29, 1978. U.S. 4, 100,429.
`Antibacterial Oral Compositions. March 1978. U.S. 4,118,472.
`Antibacterial Oral Compositions. October 3, 1978. U.S. 4,118,473.
`Antibacterial Oral Compositions. October 3, 1978. U.S. 4,118,474.
`Antibacterial Oral Compositions. October 3, 1978. U.S. 4,118,475.
`Antibacterial Oral Compositions. October 3, 1978. U.S. 4,118,476.
`Antibacterial Oral Compositions. October 31, 1978. U.S. 4,123, 512.
`Antibacterial Oral Compositions. January 30, 1979. U.S. 4,137, 303.
`Anticalculus Oral Composition. May 1, 1979. U.S. 4,152,420.
`Dentifrice for Dental Remineralization. December 4, 1979. U.S. 4,177,258.
`Mg/Polycarboxylate Complexes as Calculus Agent. January 15, 1980. U.S. 4,183,914.
`Stable Solution for Dental Remineralization. January 15, 1980. U.S. 4,183,915.
`Antibacterial Oral Compositions. February 15, 1980. U.S. 4,188,372.
`Anticalculus Oral Compositions. July 29, 1980. U.S. 4,215,105.
`Mg/Polycarboxylate as Anticalculus Agents. August 12, 1980. U.S. 4,217,342.
`Mg/Polycarboxylate as Anticalculus Agents. August 12, 1980. U.S. 4,211,343.
`Anticalculus Oral Composition. September 23, 1980. U.S. 4,224,308.
`Anticalculus Oral Composition. September 23, 1980. U.S. 4,224,309.
`Antigingivitis Composition. June 9, 1981. U.S. 4,272,512.
`Stabilized Oral Composition. June 9, 1983. U.S. 4,272,513.
`Antibacterial Oral Composition. June 16, 1981. U.S. 4,272,759.
`Non—staining Antigingivitis Composition. January 15, 1982. U.S. 4,309,410.
`Anticalculus Oral Composition. July 13, 1982. U.S. 4,339,431.
`Antigingivitis Composition Compromising Vinyl Phosphonic Acid / Vinyl Phosphonyl Fluoride.
`August 3, 1982. U.S. 4,339,430.
`Antigingivitis Composition Compromising Vinyl Phosphonic Acid / Vinyl Phosphonyl Fluoride.
`August 3, 1982. U.S. 4,342,857.
`Dental Remineralization Composition. September 7, 1982. U.S. 4,348,381.
`Oral Composition Containing Antibacterial Agents. June 25, 1983. U.S. 4,370,314.
`Antigingivitis Composition. January 24, 1984. U.S. 4,427,652.
`Topical Treatment of Skin Lesions. February 7, 1984. U.S. 4,430,325.
`Oral Composition Having Mole Ratio of Tetra(methylenephosphonate) to Alkali Metal Fluoride of
`at 1,411. March 13, 1984. U.S. 4,437,721.
`Anticalculus Composition. October 2, 1984. U.S. 4,474,750.
`Oral Product for Controlling Gingivitis. April 30, 1985. U.S. 4,514,382.
`Peroxydiphosphate Toothpaste Composition. August 27, 1985. U.S. 4,587,765.
`Anticalculus Oral Composition Containing Phosphonoformic Acid. May 20, 1986.
`U.S. 4,590,040.
`Anticalculus Oral Composition. December 9, 1986. U.S. 4,627,977.
`Inhibition of Tumor Development. June 14, 1985. U.K. GB2161074B.
`Composition to Counter Breath Odor. August 25, 1987. U.S. 4,689,214.
`Antiplaque/Antigingivitis Method Using Certain Polyphosphonic Acids. March 28, 1989.
`U.S. 4,816,245.
`Anticalculus Oral Compo