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`1
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`Current to March 2014
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`Dr. George G. ZHANEL, FCCP
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` Box 13, Grp 615 SS6
` Winnipeg, Manitoba, Canada
` R2C 2Z3
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` (204) 256-0682
` (204) 257-0710
` ggzhanel@pcs.mb.ca
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`Ph.D. in Medical Microbiology
`University of Manitoba
`Faculty of Medicine
`Winnipeg, Manitoba, Canada
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`PERSONAL INFORMATION
`Mailing Address: MS673-Microbiology, 820 Sherbrook St. Home Address:
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`Health Sciences Centre
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` Winnipeg, Manitoba, Canada
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`R3A 1R9
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` Phone:
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`Phone:
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`(204) 787-4902
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` Fax:
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`Fax:
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`(204) 787-4699
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` Email:
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`Email:
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`ggzhanel@pcs.mb.ca
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`April 18, 1962
`Birth Date:
`Olomouc, Czechoslovakia
`Birth Place:
`Marital Status: Married (2 sons Stefan-1992 and Michael-1994)
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`ACADEMIC QUALIFICATIONS
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`1994
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`1986
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`Doctor of Clinical Pharmacy (magna cum laude)
`University of Minnesota
`Minneapolis, Minnesota, USA
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`CURRENT POSITIONS
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` 2013-Present
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`Course Leader – Infectious Diseases/Medical Microbiology, Undergraduate Medical
`Education (UGME), Faculty of Medicine, University of Manitoba, Winnipeg, Canada
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`Director - Canadian Antimicrobial Resistance Alliance (CARA), Faculty of Medicine,
`University of Manitoba, Winnipeg, Canada
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`Professor, Department of Medical Microbiology/Section of Infectious Diseases, Faculty of
`Medicine, University of Manitoba, Winnipeg, Canada
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`Coordinator - Antibiotic Resistance Program, Section of Infection Control, Department of
` Medicine, Health Sciences Centre, Winnipeg, Canada
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`2006-Present
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`2002-Present
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` 1994-Present
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`ALCON 2006
`Apotex Corp. v. Alcon Research, Ltd.
`Case IPR2013-00428
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`George G. Zhanel
`PREVIOUS POSITIONS
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` 1996-2006
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`2
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`Chair - Antimicrobial Resistance Research Group, Faculty of Medicine, University of
` Manitoba, Winnipeg, Manitoba, Canada
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`1999-2002
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`Associate Professor, Department of Medical Microbiology/Section of Infectious Diseases,
`Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
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`1999-2002 Professor, Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
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`1994-1999 Assistant Professor, Department of Medical Microbiology/Section of Infectious Diseases,
`Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
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`1994-1999 Associate Professor, Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba,
`Canada
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`1994-1997
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`1990-1994
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`1989-1990
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`1987-1994
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`Head - Division of Clinical Sciences and Practice, Faculty of Pharmacy, University of
`Manitoba, Winnipeg, Manitoba, Canada.
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`Doctor of Philosophy Candidate, Department of Medical Microbiology, Faculty of
`Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
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`Postdoctoral Research Fellow, Department of Medical Microbiology, Faculty of Medicine,
`University of Manitoba, Winnipeg, Manitoba, Canada
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`Assistant Professor, Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba,
`Canada
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`1987-1989 Clinical Instructor, St. Boniface General Hospital, Winnipeg, Manitoba, Canada
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`1986-1987
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`Clinical Specialist in Infectious Diseases, Health Sciences Centre, Winnipeg, Manitoba,
`Canada
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`ADMINISTRATIVE POSITIONS
`1998-1999
`Acting Dean, Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
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`1997-1999
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`Associate Dean Research, Faculty of Pharmacy, University of Manitoba, Winnipeg,
`Manitoba, Canada
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`ADDITIONAL TRAINING
`1996
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`Animal Infection Models (murine models of pneumonia, tissue cage, subcutaneous thread,
`thigh and peritonitis, rabbit models of meningitis and endocarditis) Antimicrobial
`Chemotherapy Workshop, Reykjavik, Iceland.
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`1992
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`1990
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`BRL Recombinant DNA Techniques Workshop, University of Manitoba, Winnipeg,
`Manitoba, Canada
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`Training in Dr. William Craig's Laboratory, Madison, Wisconsin. "The postantibiotic
`effect in a neutropenic mouse thigh model".
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`George G. Zhanel
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`1990
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`3
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`Training in Dr. John Hopkin's Laboratory, Madison, Wisconsin. "Urinary tract infection in
`a mouse model".
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`TEACHING EXPERIENCE
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`1987 - Present
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`University of Manitoba, Faculty of Medicine
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`Medicine I – Block 1 Infectious Diseases Session leader, 2004-Present
`- Antibiotic concepts, cell wall active antibiotics, protein synthesis inhibitors,
`other antibiotics, antibiotic resistance, antibiotic applications, pathogenesis,
`immune system, vaccines, normal microbiota, introduction to microbes,
`Enterobacteriaceae, Staphylococci, Streptococci, infectious principles
`- Tutorials on normal human microbiota, S. aureus, S. pyogenes, E. coli,
` Tuberculosis/antitubercular agents, viral infections/antivirals, infection
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` prevention/public health, fungal infections/antifungals,
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` parasitic infections/antiparasitics
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` - Infectious Diseases Laboratory Session, 1991-1995
` Normal microbiota, disinfectants, sterilizers, antiseptics, vaccines
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` - Defense Mechanisms and Therapeutics, 2000 - 2004
` Antibiotic concepts, cell wall active antibiotics, protein synthesis inhibitors,
` other antibiotics, antibiotic
`resistance, antibiotic applications, disinfectants,
` sterilizers, antiseptics, vaccines
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` - Block 3 Infectious Diseases course director, 2009-Present
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`Viral infections/antivirals, influenza, respiratory infections, infections in travellers
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`and HIV/AIDS
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`Medicine II - Infectious Diseases, 1993-1999.
`- Antibiotic concepts, cell wall active antibiotics, protein synthesis inhibitors,
` other antibiotics, antibiotic resistance, antibiotic applications,
` viral infections/antivirals, preservatives, disinfectants, sterilizers, antiseptics,
` topical antibiotics, antibiotics in pregnancy
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`Medicine IV - Infectious Diseases/Antibiotic Review 2003-present.
`- Review of antibiotics and their use in the treatment of common infectious
` diseases
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`Medicine III - Mini-Hospital Microbiology Laboratory Session, 1991-1995
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`- Therapeutics in Infectious Diseases, therapeutics in pregnancy and lactation, four
` tutorials on antibiotic use in the treatment of infectious diseases, 1993-Present.
`- Infectious Diseases/Antibiotic Review 2003-present.
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` Review of antibiotics and their use in the treatment of common infectious
`
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` Diseases, new vaccines
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`Infectious Diseases Postdoctoral Fellows - 2002-present
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` Clinical Infectious Diseases Lecture Series
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` - Antibiotic resistant infections
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`George G. Zhanel
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`4
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` - Review of commonly used antibiotic classes
`- New and investigational antimicrobials
`- preservatives, disinfectants, sterilizers, antiseptics
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`Internal Medicine/Emergency Residents - 2007-present
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` Clinical Infectious Diseases Lecture Series
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` - Antibiotic resistant infections
`- New antibiotics
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`Department of Pharmacology and Therapeutics
`Pharmacology 89.713, 1995-Present
`One 3 hour seminar on cellular and molecular mechanisms of antimicrobial action
`
`Pharmacology 2100, 1995-2013
`Principles of
`therapy, penicillins/cephalosporins, carbapenems, chloramphenicol,
`tetracyclines/glycylcyclines,glycopeptides/lipopeptides,
`aminoglycosides, quinolones,
`macrolides/ketolides, monobactams, oxazolidinones, polymyxins, antitubercular drugs,
`sulfonamides and antifolates, antimicrobials with special indications, antibiotics in
`pregnancy and
`lactation,
`topical antibiotics, antiparasitic agents, preservatives,
`disinfectants, sterilizers, antiseptics,
`New vaccines
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`Pharmacology 4040, 2009-Present
`Antimicrobial selection, antimicrobial resistance
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`Department of Medical Microbiology
`The Molecular Basis of Antibiotic Action MMC 7160, 1996-Present
`Course Director
`Eight 3 hour tutorials on the cellular and molecular mechanisms of action and resistance of
`antimicrobials, antivirals and agents with antimicrobial activity including preservatives,
`disinfectants, sterilizers, antiseptics
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`Microbial Pathogenicity MMC 7050, 2004-Present
`Antibiotic resistance
`Two 3 hour lecture/tutorials on the cellular and molecular mechanisms of antibiotic
`action/resistance.
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`Ecology of Infectious Diseases MMC 7220, 2010-Present
`Introduction to infectious diseases
`Two hour lecture/tutorial on the principles and practice of infectious diseases.
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`Antibiotics in Infectious Diseases 1987-1989
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`Course Director,
`Infectious Diseases Fellows, Section of
`Diseases/Medical Microbiology, University of Manitoba
`Principles of antimicrobial chemotherapy, treatment of common infections, penicillins,
`cephalosporins,
`carbapenems, monobactam,
`aminoglycosides,
`fluoroquinolones,
`macrolides, glycopeptides, sulfonamides, tetracyclines, agents with antimicrobial activity
`including non-traditional
`antimicrobials, preservatives, disinfectants,
`sterilizers,
`antiseptics, antifungals, antivirals, antiparasitics, antitubercular agents, new vaccines
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`Infectious
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`George G. Zhanel
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`Continuing Education/Medical Microbiology, 1989, Course Instructor, Certificate in
`Infection Control in Health Care Program - Antimicrobial Pharmacology Section,
`University of Manitoba – Principles of infection prevention and agents/systems used for
`infection prevention
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`5
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`University of Manitoba, Faculty of Science
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`Microbiology - Mechanisms of Microbial Diseases (MBIO3010), 1993-Present
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`Mechanism of action and resistance of: cell wall active antibiotics, protein
`inhibitors, other antibiotics, antiviral agents, antifungal agents
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`University of Manitoba, Faculty of Pharmacy
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`Clinical Pharmacy Tutorials 46.438, 1987-1991
`Introduction, thromboembolism and cerebrovascular disease, angina pectoris/myocardial
`infarction, congestive heart failure, review tutorial, hypertension and hypertensive
`emergencies, congestive heart failure, peptic ulcer disease, rheumatoid arthritis, urinary
`tract infection, respiratory tract infection, eye/ear/nose and throat infections, clinical
`toxicology
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`Therapeutics 46.435, 1987-1991
`lectures), principles of oncology &
`Arrhythmias and antiarrhythmic agents (2
`chemotherapy (4 lectures), AIDS - acquired immunodeficiency syndrome
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`Antibiotics in Infectious Diseases 46.443, 1991-1994; 46.341, 1994-1998
`Course Director
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`Introduction to microbiology, infectious diseases and the microbiology laboratory,
`penicillins,
`cephalosporins, other beta-lactams, vancomycin,
`aminoglycosides,
`fluoroquinolones, sulfonamides,
`tetracyclines, antiviral agents, antifungal agents,
`antitubercular agents, antiparasitic agents, agents used for urinary tract infections,
`treatment of HIV/AIDS, treatment of respiratory infections, treatment of ear infections,
`prevention and treatment of eye infections, prevention and treatment of dental infections,
`prophylaxis for travelers, treatment of viral infections, mechanisms of antibiotic resistance,
`antibiotics in pregnancy and lactation, agents with antimicrobial activity including non-
`traditional antimicrobials, preservatives, disinfectants, sterilizers, antiseptics, new vaccines
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`Professional Practice II 46.441, 1987-1993
`Course coordinator for hospital dispensing section
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`Drug Induced Diseases 46.451, 1995-1996
`Course Director
`Thirteen 3 hour seminars/tutorials regarding issues in infectious diseases therapeutics.
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`Drug Information 46.342, 1995-1996
`Three 2 hour seminars/tutorials regarding drug literature evaluation
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`Advanced Topics: Antibiotics and the Treatment of Infectious Diseases 46.709,
`1996-1998
`Thirteen 3 hour seminars/tutorials regarding infectious diseases therapeutics issues.
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`6
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`George G. Zhanel
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`Medical and Scientific Writing 46.711, 1996-2003
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`Course Director
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`Pharmaceutical Sciences Laboratory 46.452, 1996-2002
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`Two day laboratory session on biotechnology
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`Medicinal Chemistry IV - Drug Design 46.453, 1996-2002
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`Two hours on cellular and molecular mechanisms of action and resistance of bacteria
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`Medicinal Chemistry 46.340, 1997-1998, 2001-2002
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`Twelve hours on structure/activity relationships of antimicrobial agents, antivirals,
`preservatives, disinfectants, sterilizers, antiseptics
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`Continuing Education, Department of Pharmacy, St. Boniface Hospital 1988
`Course Director
`Therapeutics of cancer and cancer chemotherapy, musculoskeletal diseases, eye ear nose
`and throat infections
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`SUMMER STUDENT SUPERVISION
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`2014
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`2013
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`University of Manitoba, School of Nursing
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`Prevention of Illness and Disability in Nursing II 49.414, 1988-1995
`Use of pharmacological agents during labour and delivery
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`Health Restoration in Nursing III 49.329, 1992-1996
`Antimicrobial agents commonly used in nursing, drugs in pregnancy and lactation.
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`Nurse Practitioner Program 2010-present
`Treating in commonly encountered infectious diseases.
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`Continuing Education, Department of Nursing, St. Boniface General Hospital 1988
`Course Director
`Therapeutics of cardiovascular diseases (Medical wards only)
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`Red River Community College
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`Medical Laboratory Technology Program 2007-Present
`Antimicrobial resistant infections/New antimicrobials
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`Shivangi Vashisht, Microbiology Co-op Student
`Project: Ribotyping of Clostridium difficile from across Canada
`Support: Optimer/Cubist
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`Tyler Denisuik, Summer Research Student
`Project: Virulence assessment of invasive Streptococcus pneumoniae
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`7
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`Nikesh Tailor, Summer Research Student
`Project: CANWARD 2013
`Support: Multi-Industry
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`George G. Zhanel
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`Support: Vice-President Research (University of Manitoba)
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`2013
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`2013
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`2013
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`2013
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`2013
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`2012
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`2012
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`2012
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`2012
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` 2012
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`2011
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`Shivangi Vashisht, Microbiology Co-op Student
`Project: Ertapenem pharmacodynamics versus ESBL producing E. coli at standard and
`high inocula
`Support: Merck
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`Jordan Dupuis, Summer Research Student
`Project: CANWARD 2013
`Support: Multi-industry
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`Chris Yachison, Summer Research Student
`Project: Activity of ampicillin/sulbactam versus pathogens in Canadian hospitals
`Support: Pfizer
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`Phillip Chung, Summer Research Student
`Project: Review paper on Ceftolozane/tazobactam
`Support: Cubist
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`Chris Yachison, BSc Honors Project
`Project: Characterization of MRSA in Canadian hospitals 2010/2011
`Support: Multi-Industry
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`Chris Lawson, Summer Research Student
`Project: Review paper on Ceftazidime/avibactam
`Support: AstraZeneca
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`Alyssa Golden, Summer Research Student
`Project: Characterization of serotypes, antimicrobial resistance and virulence of
`Streptococcus pneumoniae across Canada in 2012 (SAVE 2012)
`Support: Canadian Foundation for Infectious Diseases (CFID)
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`Margot Rosenthal, Summer Research Student
`Project: CANWARD 2012
`Support: Multi-Industry
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`Leanne Scharikow, Microbiology Co-op Student
`Project: Characterization of serotypes, antimicrobial resistance and virulence of
`Streptococcus pneumoniae across Canada in 2011 (SAVE 2011)
`Support: Multi-Industry
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`Chris Yachison, Summer Research Student
`Project: Pharmacodynamic modeling of ertapenem, ceftaroline and comparators against
`resistant pathogens
`Support: Cerexa/Merck
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`George G. Zhanel
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`2011
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`2011
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`2011
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`2011
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`2010
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`2010
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`2010
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`2010
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`2010
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`2010
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`2010
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`2009
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`8
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`Chris Lawson, Summer Research Student
`Project: Review paper on ACHN-490 and aminoglycosides
`Support: Achaogen
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`Leanne Scharikow, Summer Research Student
`Project: CANWARD 2011
`Support: Multi-industry
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`Andrew Denisuik, Summer Research Student
`Project: CANWARD 2011
`Support: Multi-industry
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`Aaron Onio, Microbiology Co-op Student
`Project: Characterization of hVISA in Canadian hospitals CANWARD 2007-2010
`Support: Multi-Industry/National Microbiology Laboratory
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`Kali Teichroeb, Microbiology Co-op Student
`Project: Characterization of ESBL-producing E. coli in Canadian hospitals CANWARD
`2010
`Support: Multi-Industry
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`Emma Rossnagel, Summer Research Student
`Project: Biological activity of aminoglycoside fusion antimicrobials
`Support: CIHR
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`Ben Fultz, BSc Med Student
`Project: Characterization of penicillin-resistant multi-drug resistant Streptococcus
`pneumoniae in Canadian hospitals
`Support: CIHR/MMSF
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`Sheila Felsch, Summer Research Student
`Project: Pharmacodynamic modeling of ceftobiprole and ceftaroline against resistant
`pathogens
`Support: Multi-industry
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`Lauren Cox, Summer Research Student
`Project: CANWARD 2010
`Support: Multi-Industry
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`Michael Onotera, Summer Research Student
`Project: Biological activity of aminoglycoside fusion antimicrobials
`Support: CIHR
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`Sara Kost, Microbiology Co-op Student
`Project: Assessment of hetero-resistant VISA from MRSA in Canadian hospitals
`Support: Multi-Industry
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`Kristjan Thompson, BSc Med Student
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`George G. Zhanel
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`Project: Molecular characterization of community-associated methicillin-resistant
`Staphylococcus aureus (CA-MRSA)
`Support: CIHR/MMSF
`Project Awards: Dr. Jack Wilt Memorial Award; Dr. Norman and Margaret Corne Award
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`2009
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`2009
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`2009
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`2009
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`2009
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`2008
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`2008
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`2008
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`2008
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`2008
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`Shelley Petersen, Summer Research Student
`Project: Molecular epidemiology of MDR ESBL E. coli in Canada
`Support: Multi-industry
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`Divna Calic, Summer Research Student
`Project: Review paper on oritavancin
`Support: Targanta
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`Lauren Cox, Summer Research Student
`Project: Pharmacodynamic modeling of tigecycline, ceftobiprole and doripenem against
`resistant pathogens
`Support: Wyeth and Ortho McNeil
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`Lisa Bittner, Summer Research Student
`Project: CANWARD 2009
`Support: Multi-industry
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`Leanne Scharikow, Summer Research Student
`Project: CANWARD 2009
`Support: Multi-industry
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`Dylan Voth, Summer Research Student
`Project: Pharmacodynamics of vancomycin and ceftobiprole against MRSA, VISA and
`VRSA
`Support: Janssen Ortho
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`Lisa Bittner, Summer Research Student
`Project: CANWARD 2008 study
`Support: Pfizer
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`Amanpreet Singh, Summer Research Project
`Project: Characterization of fluoroquinolone resistance mechanism in E. coli from
`CANWARD (assessment of qnr, aac6´cr and qepA)
`Support: Manitoba Health Research Council (MHRC)
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`Kristjan Thompson, BSc Med Student
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`Project: Molecular characterization of community-associated methicillin-resistant
`Staphylococcus aureus (CA-MRSA)
`Support: CIHR/MMSF
`Project Awards: Dr. Norman and Margaret Corne Award
`
`
`
`
`Grace Sniezek, Summer Research Student
`Project: Review of ceftaroline
`Support: Cerexa/STI
`
`
`
`
`
`
`
`
`
`
`10
`
`George G. Zhanel
`2008
`
`Haley Butcher, Summer Research Student
`Project: CANWARD 2008 study
`
`
`
`
`
`
`Support: Wyeth
`
`2007
`
`
`
`
`
`
`Erin Becker, BSc Med Student
`Project: Molecular characterization of multi-drug resistant E. coli urinary tract isolates
`from North America
`Support: CIHR
`
` Project Awards: Morris Neaman Award, Dr. Jack Wilt memorial award, Midwest
` research forum travel award
`
`
`
`
`
`Nick Chiu, Microbiology Co-op Student
`Project: Assessment of vancomycin MIC creep in bacteremic MRSA and MRSE
`Support: Multi-Industry
`
`
`
`
`
`2007
`
`
`
`
`
`
`2007
`
`
`
`
`
`2007
`
`
`
`
`
`2007
`
`
`
`
`
`2007
`
`
`
`
`
`2007
`
`
`
`
`
`
`2007
`
`
`
`
`
`2006
`
`
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`
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`2006
`
`
`
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`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`Franil Tailor, Summer Research Student
`Project: CANWARD study
`Support: Multi-Industry
`
`Stacie Langster, Summer Research Student
`Project: CANWARD study
`Support: Multi-Industry
`
`Ashley Lam, Summer Research Student
`Project: Review on ceftobiprole
`Support: Ortho McNeil
`
`Shannon Trapp, Summer Research Student
`Project: Review on dalbavancin, telavancin
`Support: Astellas
`
`Vibhu Vashisht, Summer Research Student
`Project: Mutant prevention concentration with antibiotic combinations versus
`Pseudomonas aeruginosa
`Support: Ortho McNeil
`
`Kristjan Thompson, Summer Research Student
`Project: CANWARD Study
`Support: Multi-Industry
`
`
`
`
`Erin Becker, BSc Med Student
`Project: Molecular characterization of multi-drug resistant E. coli urinary tract isolates
`from North America
`Support: CIHR
`
` Project Award: Morris Neaman Award
`
`
`
`
`
`Ryan Wiebe, Summer Research Student
`Project: Review on carbapenems
`Support: Merck, Ortho McNeil
`
`
`
`George G. Zhanel
`2006
`
`Sam Kasloff, BSc Honors Project
`
`
`
`Project: Molecular epidemiology of North American urinary isolates of multi-drug
`resistant Escherichia coli
`Support: Procter and Gamble
`
`
`
`
`
`2006
`
`
`
`
`
`2006
`
`
`
`
`
`
`
`2005
`
`
`
`
`
`
`
`2005
`
`
`
`
`
`
`
`
`2005
`
`
`
`
`
`2005
`
`
`
`
`
`2005
`
`
`
`
`
`
`
`2005
`
`
`
`
`
`
`
`2005
`
`
`
`
`
`2005
`
`
`
`11
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`Leanne Dilay, Summer Research Student
`Project: Review on piperacillin/tazobactam
`Support: Wyeth
`
`Kristjan Thompson, Summer Research Student
`Project: Mutant prevention concentration with antibiotic combinations versus
`Pseudomonas aeruginosa
`Support: Internal
`
`Sam Kasloff, BSc Honors Project
`Project: Molecular epidemiology of North American urinary isolates of multi-drug
`resistant Escherichia coli
`Support: Procter and Gamble
`
`
`
`
`Xi Wang, BSc Med Student
`Project: Molecular characterization of multi-drug resistant pediatric Streptococcus
`pneumoniae from Canada 1997-2003
`Support: CIHR
`
` Project Awards: Morris Neaman Award, Dr. Jack C. Wilt Memorial Award (Best
` Project in Infectious Diseases) and Midwest Student Research Forum Award
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`Matt Mayer, Summer Research Student
`Project: Molecular epidemiology of fluoroquinolone-resistant E.coli in North America
`Support: Procter and Gamble
`
`Sonya Fontaine, Summer Research Student
`Project: Review of fluoroquinolones in the treatment of infectious diseases
`Support: Bayer and Bristol Myers Squibb
`
`Ryan Wiebe, Summer Research Student
`Project:
`Pharmacodynamics
`of
`garenoxacin
`S.pneumoniae in clinical isolates
`Support: Internal
`
`versus
`
`fluoroquinolone-resistant
`
`Sam Kasloff, Summer Research Student
`Project: Pharmacodynamics of ertapenem versus high
`S.pneumoniae
`Support: Merck
`
`level penicillin-resistant
`
`Kathy Karlowsky, Summer Research Student
`Project: Canadian Respiratory Organism Susceptibility Study (CROSS)
`Support: Pfizer
`
`Ben Lulasnyk, Microbiology Co-op Student
`Project: Molecular mechanisms of fluoroquinolone-resistant S.pneumoniae in clinical
`isolates
`
`
`
`George G. Zhanel
`
`
`
`Support: Internal
`
`2005
`
`
`
`
`
`
`
`
`
`12
`
`Andrew Walkty, Internal Medicine Resident
`Project: Characterization of multi-drug resistant S. pneumoniae
`Support: Wyeth
`Award: First prize, Residents research day (clinical investigation poster) and selected
`for presentation at Canadian Society for Clinical Investigation/Canadian
`Association of Professors of Medicine Resident Research Awards Competition
`
`Joann James, Microbiology Co-op Student
`Project: Pharmacodynamics of telithromycin versus macrolide-resistant S.pneumoniae
`Support: Sanofi-Aventis
`
`Matt Mayer, BSc Honors Project
`Project: Mutant prevention concentration (MPC) using combination antibiotics against
`Pseudomonas aeruginosa
`Support: Internal
`
`Samol Moung, Microbiology Co-op Student
`Project: Pharmacodynamics of fluoroquinolones in a simulated colon model
`Support: Internal
`
`Kevin Collins, Microbiology Co-op Student
`Project: Mutational rates of macrolides and ketolides with S.pneumoniae
`Support: Internal
`
`Jennie Greisman, Summer Research Student
`Project: Sequencing of ketolide/macrolide resistant S.pneumoniae
`Support: Internal
`
`Matt Mayer, Summer Research Student
`Project: Pharmacodynamics of fluoroquinolones against Pseudomonas aeruginosa
`Support: Internal
`
`Laura Danyluk, Microbiology Co-op Student
`Project: Pharmacodynamics of fluoroquinolones with and without metronidazole versus
`Bacteroides fragilis
`Support: Internal
`
`Haider Arishi, Pediatric Infectious Diseases Fellow
`Project: Serotyping of multi-drug resistant S. pneumoniae
`Support: Wyeth
`
`Sheldon Derkatch, Summer Research Student
`Project: Pharmacodynamics of Iclaprim and Trimethoprim/Sulfamethoxazole against
`Streptococcus pneumoniae
`Support: Arpida
`
`Jamie Rusen, Summer Research Student
`
`
`2005
`
`
`
`
`
`2004
`
`
`
`
`
`
`
`2004
`
`
`
`
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`2004
`
`
`
`
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`2004
`
`
`
`
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`2004
`
`
`
`
`
`2004
`
`
`
`
`
`
`
`2004
`
`
`
`
`
`2004
`
`
`
`
`
`
`
`2004
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`George G. Zhanel
`13
`Project: DNA sequencing of L4, L22 and 23srRNA in ketolide-resistant Streptococcus
`
`
`
`pneumoniae
`Support: Internal
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
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`
`
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`
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`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`Xi Wang, BSc Med Student
`Project: Molecular characterization of multi-drug resistant pediatric Streptococcus
`pneumoniae from Canada 1997-2003
`Support: CIHR
`Project Awards: Morris Neaman Award
`
`Kathy Karlowsky, Summer Research Student
`Project: Surveillance of antibiotic resistant pathogens in Canada
`Support: Abbott and Aventis
`
`Brian Milligan, Summer Research Student
`Project: Surveillance of antifungal resistant pathogens in Canada
`Support: Pfizer
`
`Kristen Schurek, Summer Research Student
`Project: DNA sequencing of fluoroquinolone-resistant Streptococcus pneumoniae from
`Canada 1997-2003
`Support: Ortho-McNeil
`
`Crystal Johansen, Summer Research Student
`Project: Review on ertapenem
`Support: CIHR/Merck
`
`Vanessa Goleski, Microbiology Co-op Student
`Project: Pharmacodynamics of fluoroquinolones with and without metronidazole versus
`Bacteroides fragilis
`Support: Internal
`
`Jennifer Tam, Microbiology Co-op Student
`Project: Mutant prevention concentration of macrolides versus ketolides against
`Streptococcus pneumoniae
`Support: Internal
`
`Sarah Tohme, Microbiology Co-op Student
`Project: Single-step and multi-step resistance development with macrolides and ketolides
`versus wild-type and mefE Streptococcus pneumoniae
`Support: Aventis
`
`Melissa Goolia, Microbiology Co-op Student
`Project: Pharmacodynamics of fluoroquinolones with and without metronidazole versus
`Bacteroides fragilis
`Support: Internal
`
`Chris Mendoza, Summer Research Student
`Project: Review of garenoxacin
`Support: BMS
`
`
`
`
`
`2004
`
`
`
`
`
`
`
`
`
`2004
`
`
`
`
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`2004
`
`
`
`
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`2004
`
`
`
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`
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`2004
`
`
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`
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`2004
`
`
`
`
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`
`
`2004
`
`
`
`
`
`
`
`2003
`
`
`
`
`
`
`
`2003
`
`
`
`
`
`
`
`2003
`
`
`
`
`
`
`
`George G. Zhanel
`
`2003
`
`
`
`
`
`
`14
`
`Jamie Rusen, Summer Research Student
`Project: Pharmacodynamics of ketolides against ketolide resistant Streptococcus
`pneumoniae
`Support: Aventis
`
`Christel Johansen, Summer Research Student
`Project: Pharmacodynamics of garenoxacin against fluoroquinolone-resistant (ParC, efflux
`and GyrA mutants) Streptococcus pneumoniae
`Support: BMS
`
`Carrie Selin, Microbiology Co-op Student
`against
`Project: Pharmacodynamics of AR-100
`trimethoprim-resistant Streptococcus pneumoniae
`Support: Arpida
`
`trimethoprim-susceptible
`
`and
`
`Kristen Schurek, Summer Research Student
`Project: Molecular characterization of fluoroquinolone resistant Streptococcus pneumoniae
`Support: Internal
`
`Christine Dueck, Summer Research Student
`Project: Characterization of non mef and non-erm macrolide resistant Streptococcus
`pneumoniae
`Support: Abbott
`
`Dean Swedlo, B.Sc.Med. Research Student
`Project: Molecular evolution of macrolide-resistance in S.pneumoniae in North America
`Support: CIHR studentship
`Project Awards: Nicholson Prize for greatest scientific merit and travel award
`
`Kathy Karlowsky, Summer Research Student
`Project: Canadian Respiratory Organism Susceptibility Study (CROSS)
`Support: Abbott
`
`Rhiannon Harris, Microbiology Co-op Student
`Project: Pharmacodynamics
`of macrolides/ketolides
`Haemophilus influenzae
`Support: internal
`
`Andy Cumming, Summer Research Student
`Project: Impact of antibiotics on normal colonic flora
`Support: Career Placement
`
`against
`
`hyper-susceptible
`
`Dean Swedlo, B.Sc.Med. Research Student
`Project: Molecular evolution of macrolide-resistance in S.pneumoniae in North America
`Support: CIHR studentship
`
`Chris Mendoza, Summer Research Student
`Project: Pharmacodynamics of antibiotics against Haemophilus influenzae
`Support: internal
`
`
`
`
`
`2003
`
`
`
`
`
`
`
`2003
`
`
`
`
`
`
`
`2003
`
`
`
`
`
`2003
`
`
`
`
`
`
`
`2003
`
`
`
`
`
`
`
`2003
`
`
`
`
`
`2002
`
`
`
`
`
`
`
`2002
`
`
`
`
`
`2002
`
`
`
`
`
`
`2002
`
`
`
`
`
`
`
`
`
`
`
`
`
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`
`
`
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`
`
`
`
`
`
`
`
`
`
`
`
`
`15
`
`
`
`
`
`George G. Zhanel
`2002
`
`Kristen Homeniuk, Summer Research Student
`
`
`
`Project: Review of glycylcyclines
`
`
`
`Support: Wyeth
`
`
`
`
`
`
`
`
`
`2001
`
`Brad Bewick, Summer Research Student
`Project: Pharmacodynamics of B-Lactams vs. penicillin-resistant S.pneumoniae
`
`
`
`
`
`
`Support: CIHR studentship
`
`2001
`
`
`
`
`
`
`
`
`
`
`
`
`Andrew Walkty, B.Sc.Med. Research Student
`Project: Characterization of clinical S.pneumoniae isolates resistant to fluoroquinolones
`Support: MRC Studentship
`Project Awards: MMSF, Nicholson Prize for greatest scientific merit and MSD
`Scholarship
`
`
`2001
`
`
`
`
`
`2001
`
`
`
`
`
`2001
`
`
`
`
`
`2001
`
`
`
`
`
`2000
`
`
`
`
`
`2000
`
`
`
`
`
`2000
`
`
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`
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`
`
`2000
`
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`
`
`2000
`
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`
`
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`
`
`
`
`
`
`
`
`
`
`
`
`
`
`Mike Walters, Summer Research Student
`Project: Review of ketolides: focus on respiratory infections
`Support: Aventis/Abbott
`
`Danielle Roberts, Summer Research Student
`Project: Pharmacodynamics of Macrolides/Ketolides and fluoroquinolones vs H.influenzae
`Support: internal
`
`Michelle Sill, Summer Research Student
`Project: Molecular fingerprinting of vancomycin-resistant Enterococci (VRE)
`Support: Procter Gamble
`
`Melanie DeCorby, Summer Research Student
`Project: Pharmacodynamics of nitrofurantoin vs. urinary tract pathogens
`Support: Procter Gamble
`
`Danielle Roberts, Summer Research Student
`Project: Pharmacodynamics of Macrolides/Ketolides vs mefA and ermB S.pneumoniae
`Support: internal
`
`Kelly Ennis, Summer Research Student
`Project: Review paper on new fluoroquinolones
`Support: Careerstart Grant
`
`Andrew Walkty, B.Sc.Med. Research Student
`Project: Characterization of clinical S.pneumoniae isolates resistant to fluoroquinolones
`Support: MRC Studentship
`Project Award: MMSF BSc Med Award
`
`Michael Walters, Summer Research Student
`Project: Molecular mechanisms of fluoroquinolone resistance in S.pneumoniae
`Support: MRC Studentship
`
`Coleen Schroeder, Summer Research Student
`Project: Review paper on oxazolidinones
`Support: Careerstart Grant/Pharmacia
`
`
`
`16
`
`
`
`
`
`Maria Dueck, Summer Research Student
`Project: Review paper on macrolides/ketolides
`Support: Careerstart Grant/Pfizer
`
`George G. Zhanel
`
`1999
`
`
`
`
`
`1999
`
`
`
`
`
`1999
`
`
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`
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`1999
`
`
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`
`
`1998
`
`
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`
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`1998
`
`
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`
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`1998
`
`
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`
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`1998
`
`
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`
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`1998
`
`
`
`
`
`1997
`
`
`
`