CURRICULUM VITAE
`
`
`Name:
`Position:
`
`
`
`
`
`Office Address
`
`
`
`Phone #:
`Email
`Education:
`
`
`
`
`
`Soumyajit Majumdar
`Associate Professor, Pharmaceutics
`Research Associate Professor, Research Institute of Pharmaceutical
`Sciences
`Associate Director, Pii Center for Pharmaceutical Technology
`Associate Director, Biopharmaceutics-Clinical and Translational Core
`Co-Director Hands-on Course in Tablet Technology
`111 Faser Hall
`Department of Pharmaceutics
`The University of Mississippi
`University, MS, 38677.
`(662) 915-3793 (O)
`majumso1@gmail.com
`Bachelor of Pharmacy, 1989
`Jadavpur University, Calcutta, India
`Master of Pharmacy, 1991
`Jadavpur University, Calcutta, India
`Doctor of Philosophy, 2005
`Pharmaceutical Sciences and Pharmacology
`University of Missouri-Kansas City, MO, USA.
`
`
`
`PROFESSIONAL EXPERIENCE
`7/12 – to date Organization: The University of Mississippi
`: Associate Director, Pii Center for Pharmaceutical Technology
`Title
`7/11 – to date Organization: The University of Mississippi
`: Associate Professor, Department of Pharmaceutics, School of
`Title
`Pharmacy and Research Associate Professor, RIPS
`7/05 – 6/11 Organization: The University of Mississippi
`: Assistant Professor, Department of Pharmaceutics, School of
`Title
`Pharmacy. and Research Assistant Professor, RIPS
`6/99 to 7/00: Company: Orchid Healthcare, Chennai, India
`Deputy Manager Formulation Development
`
`
`Title:
`
`Novartis Enterprises Pvt. Ltd. Mumbai, India
`5/97 to 6/99 Company:
`Senior Executive (Group Leader) Research and
`
`
`Title:
`
`Development
`Executive, Research and Development (Sandoz India
`
`Title:
`93 to 4/97
`
` Ltd.which became Novartis)
`Production Officer (Sandoz India Ltd.)
`
`4/92 to 93
`Title:
`
` Management Trainee, Manufacturing (Sandoz India Ltd.)
`
`6/91 to 4/92 Title:
`1
`
`
`
`
`
`
`
`
`
`ALCON 2004
`Apotex Corp. v. Alcon Research, Ltd.
`Case IPR2013-00428
`
`

`

`ACHIEVEMENTS:
`
`AWARDS / HONORS
`Bachelor of Science in Pharmaceutical Sciences Teacher of the Year, The University of
`Mississippi, 2011-2012
`New Investigator Research Award, The University of Mississippi, 2010-2011
`Associates Grant Award. The University of Mississippi, 2007 – 2008
`
`Faculty Research Fellowship Award, The University of Mississippi, 2006 – 2007
`AAiPS Research Award, 2004, from American Association of Indian Pharmaceutical
`Scientists (AAiPS).
`School of Graduate Studies Distinguished Dissertation Fellowship Award, University of
`Missouri-Kansas City (UMKC), 2004-2005.
`Dean’s Doctoral Scholar Fellowship, UMKC, 2003-2004
`Outstanding Leadership Award in 2003 from School of Pharmacy, UMKC.
`Outstanding Leadership Award in 2002 from School of Pharmacy, UMKC.
`Chancellor’s Non-Resident (CNR) Award, UMKC, 2000 – 2005.
`University gold medal for standing first in the M.S. program in the Division of
`Pharmaceutical Technology, Jadavpur University, Calcutta, India.
`Scholarship from the University Grants Commission (Govt. of India) for the duration of
`the M.S. program (1989-1991).
`
`
`
`
`
`
`COURSES TAUGHT
`
`
`• PHAR 331, Basic Pharmaceutics (3 Credit hours), Course Director
`• PHAR 433, Industrial Pharmacy (Elective; 2 Credit hours), Course Director
`• PHAR 660, Advanced Pharmacokinetics (3 Credit hours), Course Director
`• PHAR 541 (2 Credit hours), Course Director
`• PRCT 353 (2 Credit hours), Skills Lab I Course co-Instructor (about 30% course load)
`• PHAR 649 – Product Development (3 Credit hours), Course Instructor
`• PHAR 434, Biopharmaceutics and Pharmacokinetics, 2005-2006 Spring (3 Credit hours)
`Co-Instructor (30% course load)
`
`Page 2 of 25
`
`

`

`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`3/27/06 – 4/26/06
`
`10/07/05 – 12/06/05
`
`
`
`
`
` 09/2010 - 02/2011
`
`
`
`RESEARCH GRANTS
`Completed Projects
`
`Oral Absorption of Hesperidin
`Next Pharmaceuticals, Inc.
`The major goal of this project was to research factors affecting oral absorption of hesperidin.
`Principal Investigator: S. Majumdar
`
`
`Berberine Project
`Next Pharmaceuticals, Inc.
`The major goal of this project was to study and improve dissolution of berberine.
`Principal Investigator: S. Majumdar
`
` 09/2006-09/2009
`
`P20 RR021929 (Matsumoto/Cutler) NCRR/NIH
`Center of Research Excellence in Natural Products Neuroscience (CORE-NPN)
`Individual Project Proposal: “Characterization, Formulation and Evaluation of THC Pro-drugs
`for Oral Transmucosal Delivery”
`PI of Individual Project: Repka, M.A.
`Co-PI of Individual Project: Majumdar, S
`
`
` 09/2007-02/2010
`
`
`
`
`
` R21 EY18426-01 NIH/NEI
`
`Localized modulation of RPE P-gp/MRP activity for back-of-the-eye drug delivery.
`Principal Investigator: S. Majumdar
`
`
`Equipment for Center for Thermal Pharmaceutical Processing 06/01/2008-09/30/2010
`
`(Health Resources and Services Administration) (Repka, M.A)
`Co-Principal Investigator: S. Majumdar
`
`Small Grant Project (Majumdar, S)
` 07/2007 – 06/2011
`
`Awarded through NIH/NCRR grant award P20 RR021929 (Cutler) Center of Research
`Excellence in Natural Products Neuroscience (CORE-NPN)
`
`
`Small Grant Project Title: Vitreo-retinal hesperidin concentrations following topical or oral
`administration
`Principal Investigator: S. Majumdar
`
`Center for Thermal Pharmaceutical Processing Phases I & II
`(Health Resources and Services Administration) (Repka, M.A)
` Co-Principal Investigator: S. Majumdar
`
`
` 09/2008 - 08/2011
`
`
`Hot-Melt Extrusion Feasibility Studies for AR-12:
`Preformulation and Accelerated Stability
`Co-Investigator: S. Majumdar
`Other Involvement: REPKA, MICHAEL A - Principal investigator
`Award Type: Business and Industry
`Category: Research
`Granting Agency: Other
`
`
`
`Page 3 of 25
`
`

`

` 06/2008 – 05/2012
`
`
`
`2 R42 GM067304-02 (ElSohly) NIH/NIGMS
`Project Title: Transmucosal Intra-Oral Drug Delivery System for THC
` Co-Principal Investigator: S. Majumdar
`
` 06/2008 – 05/2012
`
`Supplement to 2 R42 GM067304-02 (ElSohly) NIH/NIGMS
`Project Title: Transmucosal Intra-Oral Drug Delivery System for THC
` Co-Principal Investigator: S. Majumdar
`
`
`
`Center for Thermal Pharmaceutical Processing (CTP2) Phase III
`Principal Investigator: M.A. Repka
`Co-Principal Investigator: S. Majumdar
`Agency: DHHS
`
`
`
`1R41EY020042-01A1 Development of Tetrahydrocannabinol
`prodrugs for topical treatment of Glaucoma”
`Principal Investigator at Research Institution: S. Majumdar
`Agency: NIH/NEI
`
`Technology Commercialization Initiative Fund
`Controlled Release Ophthalmic Formulations
`Principal Investigator of Project: S. Majumdar
`
`
` 09/2010 - 08/2013
`
` 03/2011-02/2013
`
`
`
`
`
` 04/2013 – 09/2013
`
`
`Current Projects
`
`
`
`P20 GM104932 Center of Research Excellence in Natural
`Product Neuroscience
`Program Director: S. Cutler
`Principal Investigator Project 3: S. Majumdar
`Project 3 Title: Delta-8-Tetrahydrocannabinol in the management of glaucoma
`Agency: NIH/GM
`
`
`
`
`1R41AI108113-01
`
`Program Director: ElSohly M.A,
`
`
`
`
`
`
`
`
`Project PI: ElSohly M.A, Majumdar S
`
` Orally Active Formulations of DHA Dimers for the treatment of Infectious Diseases
`Agency: NIH/NIAID
`
`
`University of MS Research Foundation
`Pii Center for Pharmaceutical Technology
`Principal Investigator: S. Majumdar
`Project Director: M.A. Repka
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`09/2012 – 08/2017
`
`08/2013 – 07/2014
`
`09/2012 – 08/2017
`
`Page 4 of 25
`
`
`
`

`

`
`
`
`
`
`
`
`
`01/2010 - 12/2014
`
`
`
`
`
`Properties of HME Extruded Films containing Kollidon® VA-64
`and New Polymer, Soluplus®
`
`
`
`
`
`Principal Investigator: M. A. Repka
` Co-PI: S. Majumdar
`Agency: BASF SE
`Type: Research Contract
`
`Fundamentals Studies in the Application of Low MW Klucel® and Hot-Melt Extrusion for the
`Oral Delivery of Insoluble Drugs from Tablets, Capsules and Oral Film Dosage Forms
`Principal Investigator: M. A. Repka
`
`
`
`
`01/2010-12/2014
` Co-PI: S. Majumdar
`Agency: Ashland Aqualon
`Type: Research Contract
`
`PUBLISHED ARTICLES (PEER REVIEWED).
`
`1. Functional Expression of a Sodium Dependent Nucleoside Transporter on Rabbit Cornea:
`Role in Corneal Permeation of Acyclovir and Idoxuridine. Soumyajit Majumdar, Sriram
`Gunda and Ashim K. Mitra. Current Eye Research. 2003 Mar-Apr;26(3-4):175-83.
`2. Drug delivery to retina: challenges and opportunities. Sridhar Duvvuri, Soumyajit Majumdar
`and Ashim K. Mitra. Expert Opinion on Biological Therapy. 2003 Feb;3(1):45-56.
`3. Functional Differences in Nucleoside and Nucleobase Transporters Expressed on the Rabbit
`Corneal Epithelial Cell Line (SIRC) and Isolated Rabbit Cornea. Soumyajit Majumdar,
`Giridhar S. Tirucherai, Dhananjay Pal and Ashim K. Mitra. AAPS PharmSci. 2003;5(2):E15.
`1. Expression of Peptide Transporters on Rabbit Retina: A Strategy to Improve Retinal Delivery
`of Ganciclovir. Soumyajit Majumdar, Sreeraj Macha, Yasser Nashed and Ashim K. Mitra.
`Letters in Drug Design and Discovery. 2004;1(1):73-77.
`5. Membrane Transporter / Receptor Targeted Prodrug Design: Strategies for Human and
`Veterinary Drug Development. Soumyajit Majumdar, Sridhar Duvvuri and Ashim K. Mitra.
`Advanced Drug Delivery Reviews. 2004; 56(10): 1437-1452.
`6. Bioreversion And Oral Bioavailability Of The L-Valine Dipeptide Ester Prodrug Of
`Acyclovir, Val-Valacyclovir, In Sprague-Dawley Rats. Soumyajit Majumdar, Sridhar Duvvuri
`and Ashim K. Mitra. Clinical Research and Regulatory Affairs. 2004; 21(1); 67 – 79.
`7. Circumventing P-gp mediated cellular efflux of quinidine by prodrug derivatization. Ritesh
`Jain, Soumyajit Majumdar, Dhananjay Pal and Ashim K. Mitra. Molecular Pharmaceutics.
`2004; 1(4); 290-299.
`8. Mechanism of Ganciclovir Uptake by Rabbit Retina and Human Retinal Pigmented
`Epithelium Cell Line, ARPE-19. Soumyajit Majumdar, Sreeraj Macha, Dhananjay Pal and
`Ashim K. Mitra. Current Eye Research. 2004 Aug-Sep;29(2-3):127-36.
`9. Role of Metabolism in Ocular Drug Delivery. Sridhar Duvvuri, Soumyajit Majumdar and
`Ashim K. Mitra. Current Drug Metabolism. 2004 Dec;5(6):507-15.
`
`
`
`
`
`
`
`
`
`Page 5 of 25
`
`

`

`10. Functional Activity of a Monocarboxylate Transporter, MCT1, in the Human Retinal
`Pigmented Epithelium Cell Line, ARPE-19. Soumyajit Majumdar, Sriram Gunda, Dhananjay
`Pal and Ashim K. Mitra. Molecular Pharmaceutics. 2005 Mar-Apr;2(2):109-17.
`11. Evasion of P-gp Mediated Cellular Efflux and Permeability Enhancement of HIV-Protease
`Inhibitor Saquinavir by Prodrug Modification. Ritesh Jain, Sheetal Agarwal, Soumyajit
`Majumdar, Xiadang Zhu, Dhananjay Pal and Ashim K. Mitra. International Journal of
`Pharmaceutics. 2005 Oct 13;303(1-2):8-19.
`12. Dipeptide Monoester Ganciclovir Prodrugs for Treating HSV-1-induced Corneal Epithelial
`and Stromal Keratitis: In Vitro and In Vivo Evaluations. Soumyajit Majumdar, Yasser E.
`Nashed, Kunal Patel, Ritesh Jain, Motoki Itahashi, Donna M. Neumann, James M. Hill, and
`Ashim K. Mitra. Journal of Ocular Pharmacology and Therapeutics. 21(6):463-74; 2005.
`13. Chemical modification and formulation approaches to elevated drug transport across cell
`membranes. Soumyajit Majumdar and Ashim K. Mitra. Expert Opinion on Drug Delivery.
`2006. 3(4):511-27.
`14. Vitreal pharmacokinetics of dipeptide monoester prodrugs of ganciclovir. Soumyajit
`Majumdar, Viral Kansara, and Ashim K. Mitra. J Ocul Pharmacol Ther. 2006, 22(4):231-41.
`15. Approaches towards enhanced transepithelial drug delivery. Soumyajit Majumdar, and Ashim
`K. Mitra. Discovery Medicine. 2006, 6(36):229-33.
`tablets: effect of
`16. Formulation and evaluation of rapidly disintegrating fenoverine
`superdisintegrant.: Sunil Kumar Battu, Michael A. Repka, Soumyajit Majumdar and
`Madhusudan Rao Y. Drug Development and Industrial Pharmacy. 2007, 33(11):1225-32..
`17. Effect of Chitosan, Benzalkonium Chloride and Ethylenediaminetetraacetic acid on
`Permeation of Acyclovir Across Isolated rabbit cornea. Soumyajit Majumdar, Ketan
`Hippalgaonkar and Michael A. Repka. International Journal of Pharmaceutics. 2008, 348(1-
`2):175-8.
`18. Off-line and on-line measurements of drug-loaded hot-melt extruded films using Raman
`spectroscopy.Tumuluri VS, Kemper MS, Lewis IR, Prodduturi S, Majumdar S, Avery BA,
`Repka MA. International Journal of Pharmaceutics. 2008 Jun 5;357(1-2):77-84. Epub 2008 Feb
`2.
`19. Chemical stability and bioadhesive properties of an ester prodrug of Delta(9)-
`tetrahydrocannabinol in poly(ethylene oxide) matrices: Effect of formulation additives.
`Sridhar Thumma, Soumyajit Majumdar, Mahmoud A. ElSohly, Waseem Gul, Michael A.
`Repka. International Journal of Pharmaceutics. 2008 Oct 1;362(1-2):126-32. Epub 2008 Jul 5.
`20. Preformulation Studies of a Prodrug of Delta(9)-Tetrahydrocannabinol. Sridhar Thumma,
`Soumyajit Majumdar, Mahmoud A. ElSohly, Waseem Gul, Michael A. Repka. AAPS
`PharmSciTech. 2008;9(3):982-90. Epub 2008 Aug 28.
`21. Transcorneal Permeation of l- and d-Aspartate Ester Prodrugs of Acyclovir: Delineation of
`Passive Diffusion Versus Transporter Involvement. Soumyajit Majumdar, Tushar Hingorani,
`Ramesh Srirangam, Rama Sarma Gadepalli, John M. Rimoldi, and Michael A. Repka.
`Pharmaceutical Research. 2009 May;26(5):1261-9. PMCID: PMC2664401
`
`Page 6 of 25
`
`

`

`22. Solubility, Stability, Physicochemical Characteristics and In Vitro Ocular Tissue
`Permeability of Hesperidin: A Natural Bioflavonoid. Soumyajit Majumdar, Tushar Hingorani,
`Ramesh Srirangam. Pharmaceutical Research. 2009 May;26(5):1217-25. PMCID: PMC2664388
`23. Applications of Hot-Melt Extrusion for Drug Delivery. Michael A. Repka., Soumyajit
`Majumdar, Sunil Kumar Battu, Ramesh Srirangam, Sampada Upadhaye. Expert Opinion on
`Drug Delivery. 2008 Dec;5(12):1357-76
`24. Vitreal Kinetics of Quinidine in Rabbits in the Presence of Topically Co-administered P-gp
`Substrates/Modulators: Soumyajit Majumdar, Ketan Hippalgaonkar, Ramesh Srirangam. Drug
`Metabolism and Disposition. 2009 Aug; 37(8):1718-25. PMCID: PMC2712438
`25. Evaluation of Active and Passive Transport Processes in Corneas Extracted from Preserved
`Rabbit Eyes. Soumyajit Majumdar, Tushar Hingorani, Ramesh Srirangam. Journal of
`Pharmaceutical Sciences. 2010 Apr;99(4):1921-30. PMC Journal-In Process.
`26. Potential of the bioflavonoids in the prevention/treatment of ocular disorders. Soumyajit
`Majumdar, Ramesh srirangam. The Journal of Pharmacy and Pharmacology 2010
`Aug;62(8):951-65.
`27. Preparation and Characterization of Inclusion Complexes of a Hemisuccinate Ester Prodrug
`of Δ9-Tetrahydrocannabinol with Modified Beta-Cyclodextrins. Sampada Upadhaye, Swapnil J
`Kulkarni, Soumyajit Majumdar, Mitchell A. Avery, Waseem Gul, Mahmoud A. ElSohly. AAPS
`PharmSciTech. 2010 Jun;11(2):509-17. Epub 2010 Mar 24.
`28. Interaction between Topically and Systemically Co-administered P-glycoprotein
`Substrates/Inhibitors: Effect on Vitreal Kinetics. Ketan Hippalgaonkar, Ramesh Srirangam,
`Bharathi Avula, Ikhlas Khan, Soumyajit Majumdar. In Press. Drug Metabolism and
`Disposition.
`29. Passive asymmetric transport of hesperetin across isolated rabbit cornea. Ramesh Srirangam,
`Soumyajit Majumdar. International Journal of Pharmaceutics. 2010 Jul 15;394 (1-2):60-7. Epub
`2010 May 9
`30. Physicochemical Characterization of Berberine Chloride: A Perspective in the Development
`of a Solution Dosage Form for Oral Delivery. Sunil Kumar Battu, Soumyajit Majumdar,
`Sindhuri Maddineni, Amar G. Chittiboyina, Mitchell A. Avery, and Michael A. Repka. AAPS
`PharmSciTech. 2010 Sep;11(3):1466-75. Epub 2010 Sep 15.
`31. Enhanced Solubility, Stability and Corneal Permeation of Delta-8-Tetrahydrocannabinol in
`the presence of Cyclodextrins. Soumyajit Majumdar, Ketan Hippalgaonkar, Waseem Gul,
`Mahmoud A. ElSohly and Michael A. Repka. AAPS PharmSciTech. 2011 Jun;12(2):723-31.
`Epub 2011 Jun 3.
`32. Injectable lipid emulsions-advancements, opportunities and challenges. Ketan Hippalgaonkar,
`Soumyajit Majumdar and Viral Kansara. AAPS PharmSciTech. 2010 Dec;11(4):1526-40. Epub
`2010 Oct 26.
`33. Effect of ion pairing on in vitro transcorneal permeability of a Δ(9) -tetrahydrocannabinol
`prodrug: Potential in glaucoma therapy. Tushar Hingorani, Waseem Gul, Mahmoud A
`Elsohly, Repka MA, Majumdar S. J Pharm Sci. 2012 Feb;101(2):616-26.
`
`Page 7 of 25
`
`

`

`34. Intravitreal Kinetics of Hesperidin, Hesperetin and Hesperidin G: Effect of Dose and
`Physicochemical Properties. Ramesh Srirangam, Ketan Hippalgaonkar and Soumyajit
`Majumdar. J Pharm Sci. 2012 Apr;101(4):1631-8. doi: 10.1002/jps.23047. Epub 2012 Jan 6
`35. Stabilization of fenofibrate in low molecular weight hydroxypropylcellulose matrices
`produced by hot-melt extrusion. Weibin Deng, Soumyajit Majumdar, Abhilasha Singh, Sejal
`Shah, Mohammed NN, Seongbong Jo, Elanor Pinto, Divya Tewari, Tom Durig, Michael A
`Repka. Drug Dev Ind Pharm. 2013 Feb;39(2):290-8. doi: 10.3109/03639045.2012.679280.
`Epub 2012 Apr 23
`36. Evaluation of the Intravenous and Topical Routes for Ocular Delivery of Hesperidin and
`Hesperetin. Ramesh Srirangam, Ketan Hippalgaonkar, Bharathi Avula, Ikhlas A Khan,
`Soumyajit Majumdar.
`J Ocul Pharmacol Ther.
`2012 Dec;28(6):618-27.
`doi:
`10.1089/jop.2012.0040. Epub 2012 Jul 13.
`37. Klucel™ EF and ELF polymers for immediate-release oral dosage forms prepared by melt
`extrusion technology. Mohammed NN, Majumdar S, Singh A, Deng W, Murthy NS, Pinto E,
`Tewari D, Durig T, Repka MA. AAPS PharmSciTech. 2012 Sep 8. [Epub ahead of print]
`38. Indomethacin-loaded
`solid
`lipid nanoparticles
`for ocular delivery: development,
`characterization, and in vitro evaluation. Hippalgaonkar K, Adelli GR, Hippalgaonkar K,
`Repka MA, Majumdar S. J Ocul Pharmacol Ther. 2013 Mar;29(2):216-28. doi:
`10.1089/jop.2012.0069. Epub 2013 Feb 19.
`39. Phytochemicals in ocular health: Therapeutic potential and delivery challenges. Adelli GR,
`Srirangam R, Majumdar S. World J Pharmacol 2013; 2(1): 1
`40. Development and characterization of taste masked Efavirenz pellets utilizing hot melt
`extrusion. A. Singh, S. Majumdar, W. Deng, N.N. Mohammed, A.G. Chittiboyina, V. Raman,
`S. Shah, M.A. Repka. J. Drug Del. Sci. Tech., 23 (2) 157-163 2013
`
`41. Ocular Disposition of the Hemiglutarate Ester Prodrug of ∆9-Tetrahydrocannabinol from
`
`Various Ophthalmic Formulations. Hingorani T, Adelli GR, Punyamurthula N, Gul W,
`Elsohly MA, Repka MA, Majumdar S. Pharm Res. 2013 Jun 5. [Epub ahead of print]
`42. Formulation optimization of hot-melt extruded abuse deterrent pellet dosage form utilizing
`design of experiments., S. Maddineni, S. K. Battu, J. Morott, S. Majumdar, M. A. Repka,
`Journal of Pharmacy and Pharmacology, DOI: 10.1111/jphp.12129
`
`
`BOOK CHAPTER
`
`Transcleral Drug Delivery To The Posterior Segment Of The Eye: Particulate And Colloidal
`Formulations And Biopharmaceutical Considerations. Ramesh Srirangam and Soumyajit
`Majumdar. “Advances in Ocular Drug Delivery”. Edited by Dr. Ashim K. Mitra. Publisher:
`Research Signpost and Transworld Research Network.
`http://www.trnres.com/ebookcontents.php?id=121
`
`Recent patents and regulatory aspects on ophthalmic drug delivery systems. Soumyajit Majumdar,
`Ketan Hippalgaonkar, Tushar Hingorani, Walter G. Chambliss. "Treatise on Ocular Drug Delivery",
`Edited By: Dr. Ashim K. Mitra, ISBN: 978-1-60805-175-5.
`
`
`Page 8 of 25
`
`

`

`
`PATENTS / PATENT APPLICATIONS
`“Peptidyl Prodrugs that Resist P-glycoprotein Mediated Drug Efflux”. U.S. Patent 7,214,664.
`
`“Compositions Containing Delta-9-THC-Amino Acid Esters and Process of Preparation.” Patent
`Application filed 2008. US Application No. 13/126,606 Based on PCT Application No.
`PCT/US09/62998
`
`
`
`INVITED TALKS
`Preformulation Testing and Techniques and Early Tablet Formulation Development. Hands-on
`Course in Tablet Technology, University of Mississippi, Mississippi, March 3, 2014.
`Preformulation Testing and Techniques and Early Tablet Formulation Development. Hands-on
`Course in Tablet Technology, University of Mississippi, Mississippi, September 23, 2013.
`Modulation of Efflux Activity of P-Glycoprotein Expressed on the Retinal Pigmented Epithelium
`- Impact on Ocular Drug Delivery. Asia-ARVO 2009, Hyderabad, India. January 17, 2009
`Developing Liquid Modified Release Dosage Forms: Preformulation and Formulation
`Considerations. AAPS Annual Meeting, Washington DC, 2011
`
`
`
`POSTER PRESENTATIONS:
`
`AAPS (Association of Pharmaceutical Scientists)
`
`
`1. A Lipid Based Sustained Release Oral Dosage Form of Δ9-Tetrahydrocannabinol. N.S.
`Punyamurthula, G.R. Adelli, M. A. ElSohly, M.A. Repka and S. Majumdar. AAPS 2013.
`San Antonio, Texas, USA. November 10th 2013- 14th 2013.
`
`2.
`
`Transcorneal Permeability of Δ8-Tetrahydrocannabinol Solid Lipid Nanoparticles. N.S.
`Punyamurthula, M. A. ElSohly, M.A. Repka and S. Majumdar. AAPS 2013. San Antonio,
`Texas, USA. November 10th 2013- 14th 2013.
`3. Δ 8-Tetrahydrocannabinol Solid Lipid Nanoparticles: Ocular Disposition Post Intravitreal
`Injection. AAPS 2013. San Antonio, Texas, USA. N.S. Punyamurthula, M. A. ElSohly,
`M.A. Repka and S. Majumdar. November 10th 2013- 14th 2013.
`4. Development and In Vitro Transcorneal Permeation of Δ8-Tetrahydrocannabinol Matrix
`System. G. R. Adelli, M. A. ElSohly, M. A. Repka, S. Majumdar. AAPS 2013. San
`Antonio, Texas, USA. November 10th 2013- 14th 2013.
`5. Development of a Diclofenac Sodium - Ion Exchange Resin Complex for Ocular Delivery.
`G. R. Adelli, S. Majumdar. AAPS 2013. San Antonio, Texas, USA. November 10th 2013-
`14th 2013.
`6. Development of a Matrix System for Topical Delivery of the Bioflavonoid Hesperetin. G.
`R. Adelli, T. Hingorani, M. A. Repka, S. Majumdar. AAPS 2013. San Antonio, Texas,
`USA. November 10th 2013- 14th 2013.
`
`Page 9 of 25
`
`

`

`7.
`
`8.
`
`9.
`
`10.
`
`Ex vivo and In vivo Evaluation of Topical Hesperetin Matrix Film for Back-of-the-Eye
`Delivery. G. R. Adelli, N. S. Punyamurthula, S. Majumdar. AAPS 2013. San Antonio,
`Texas, USA. November 10th 2013- 14th 2013.
`In vivo Ocular Disposition of Δ9-Tetrahydrocannabinol-Valine-Hemisuccinate from a
`Topically Applied Polymeric Matrix System. T. Hingorani, G. R. Adelli, W. Gul, M. A.
`ElSohly, M. A. Repka, S. Majumdar. AAPS 2013. San Antonio, Texas, USA. November
`10th 2013- 14th 2013.
`Effect of Cyclodextrins on Morphological Characteristics of Isolated Rabbit Cornea. S. P.
`Balguri, G. R. Adelli, S. Majumdar. AAPS 2013. San Antonio, Texas, USA. November
`10th 2013- 14th 2013.
`In Vitro Delivery of Δ8 -Tetrahydrocannabinol Across Isolated Rabbit Corneas:
`Evaluation of Nanoemulsions. S. P. Balguri, G. R. Adelli, M. Elsohly, M. A. Repka, S.
`Majumdar. AAPS 2013. San Antonio, Texas, USA. November 10th 2013- 14th 2013.
`Influence of Supercritical Carbon Dioxide on Ketoprofen-Incorporated Hot-Melt Extruded
`Low, Molecular Weight Hydroxypropylcellulose Matrices. E. A. Ashour, B. Almutairy, V.
`Kulkarni, S. Alshehri, S. Shah, S. Majumdar, R. Bosworth, Z. John Lian, E. Pinto, V. Bi,
`T. Durig, M. A. Repka. AAPS Journal Suppl., San Antonio, TX (2013)
`12. Formulation Development and Characterization of Tablets Manufactured from Hot Melt
`Extrudates with Supercritical Carbon Dioxide Processing. E. A. Ashour, B. Almutairy, V.
`Kulkarni, A. Alshetaili, S. Shah, S. Majumdar, R. Bosworth, Z. John Lian, E. Pinto, V. Bi,
`T. Durig, M. A. Repka. AAPS Journal Suppl., San Antonio, TX (2013)
`13. Formulation and Characterization of Orally Disintegrating Tablets Containing Taste-
`Masked Sildenafil Citrate. J. T. Morott, M. B. Pimparade, S. Majumdar, V. Kulkarni, J. L.
`Zhuoyang, E. Pinto, V. Bi, T. Durig, M. A. Repka. AAPS Journal Suppl., San Antonio, TX
`(2013)
`14. Taste-Masked and Release-Modified Hot-Melt Extruded Formulations Containing
`Sildenafil Citrate. J. T. Morott, M. B. Pimparade, S. Majumdar, J. L. Zhuoyang, E. Pinto,
`V. Bi, T. Durig, M. A. Repka. AAPS Journal Suppl., San Antonio, TX (2013)
`15. Development of Pediatric and Geriatric Taste-Masked Caffeine Citrate Formulations using
`Hot-Melt Extrusion Techniques. M. B. Pimparade, J. T.Morott, V. Kulkarni, S. Majumdar,
`Z. Lian, E. Pinto, V. Bi, T. Durig, M. A. Repka. AAPS Journal Suppl., San Antonio, TX
`(2013)
`16. Pediatric and Geriatric Orally Disintegrating Tablet (ODT) Formulation Development via
`Hot-Melt Extrusion. M. B. Pimparade, J. T.Morott, V. Kulkarni, J-B. Park, S. Majumdar,
`Z. Lian, E. Pinto, V. Bi, T. Durig, M. A. Repka. AAPS Journal Suppl., San Antonio, TX
`(2013)
`17. Evaluation of hydroxypropylcellulose as a recrystallization inhibitor on solid dispersions
`using an improved Avrami equation. X. Feng, J. Lu, V. Kulkarni, S. Majumdar, B.
`Beissner, Z. J. Lian, E. Pinto, V. Bi, T. Durig, M. A. Repka. AAPS Journal Suppl., San
`Antonio, TX (2013)
`Influence of Kolliphor® P Grades (Poloxamer) on Solubility and Stability of Hot Melt
`Extruded Kollidon® VA64 Drug-incorporated Matrices. A. S. Alshetaili, B. K. Almutairy,
`
`11.
`
`18.
`
`Page 10 of 25
`
`

`

`21.
`
`22.
`
`19.
`
`E. A. Ashour, V. I. Kulkarrni, J. B. Park, S. Majumdar, A. Gryczke, K. Kolter, N.
`Langley, M. A. Repka. AAPS Journal Suppl., San Antonio, TX (2013)
`Influence of Hot Melt Extrusion Processing Parameters on the Dissolution Rate of a
`Poorly Water Soluble Drug. S. M. Alshahrani, S. M. Alshehri, V. Kulkarni, J-B. Park, S.
`Majumdar, A. Gryczke, K. Kolter, N. Langley, M. A.Repka. AAPS Journal Suppl., San
`Antonio, TX (2013)
`20. Combined influence of Hot melt extruded Soluplus® and HPMCAS on Mefenamic acid
`drug release. S. M. Alshehri, S. M. Alshahrani, B. K. Almutairy, E. A. Ashour, V.
`Kulkarni, J-B. Park, S. Majumdar, A. Gryczke, K. Kolter, N. Langley, M. A. Repka. AAPS
`Journal Suppl., San Antonio, TX (2013)
`Influence of Lutrol® F 68 and HPMCAS on Mefenamic Acid Release from Kollidon®
`VA64 Extrudates. S. M. Alshehri, S. M. Alshahrani, B. K. Almutairy, E. A. Ashour, V.
`Kulkarni, J-B. Park, S. Majumdar, A. Gryczke, K. Kolter, N. Langley, M. A. Repka.
`AAPS Journal Suppl., San Antonio, TX (2013)
`Investigation of the Effects of Hot-Melt Extrusion Screw Configuration on Solid
`Dispersions via FT-IR Hyperspectral/Chemical Imaging. J. Morott, S. Majumdar, S. N.
`Murthy, A. Gryczke, K. Kolter, N. Langley, M. A. Repka. AAPS Journal Suppl., San
`Antonio, TX (2013)
`23. The influence of hot melt extrusion processing parameters on Soluplus® based solid
`dispersion systems. X. Feng, J. Morott, X. Ye, S. Majumdar, A. Gryczke, K. Kolter, N.
`Langley, M. A. Repka. AAPS Journal Suppl., San Antonio, TX (2013)
`24. Formulation and Processing of Taste Masked Mini-tablets Prepared by Hot Melt
`Extrusion. A. S. Alshetaili, B. K. Almutairy, B. B. Alsulays, J. T. Morott, V. I. Kulkarni, J.
`B. Park, S. Majumdar, M. A. Repka. AAPS Journal Suppl., San Antonio, TX (2013)
`25. Dispersible Tablet Formulation of Mefenamic Acid by Hot Melt Extrusion. S. M.
`Alshehri, S. M. Alshahrani, B. K. Almutairy, E. A. Ashour, V. Kulkarni, J-B. Park, S.
`Majumdar, M. A. Repka. AAPS Journal Suppl., San Antonio, TX (2013)
`26. T Hingorani, G Adelli, W Gul, M.A. ElSohly, M.A. Repka, S. Majumdar. Ocular
`Bioavailability of Topically Administered Delta 9 -Tetrahydrocannabinol Hemiglutarate.
`The AAPS Journal. 14(S2), Chicago, IL (2012).
`27. T Hingorani, G Adelli, W Gul, M.A. ElSohly, M.A. Repka, S. Majumdar. Ocular
`Disposition of a Topically Instilled &[Delta]9- Tetrahydrocannabinol Prodrug. The AAPS
`Journal. 14(S2), Chicago, IL (2012).
`28. G Adelli, N Punyamurthula, S. Jo, W Gul, M.A. ElSohly, M.A. Repka, S. Majumdar. J
`Nah, J Mi. Transcorneal Permeation of &[Delta]9-tetrahydrocannabinol Hemiglutarate:
`Effect of Surfactants, Cyclodextrins and Chitosan. The AAPS Journal. 14(S2), Chicago, IL
`(2012).
`29. S. Maddineni, X. Feng, S. Majumdar, M. Rahman, Zh. Lian, D. Tewari, V. Bi, T.
`Durig, M.A. Repka. Formulation Optimization of Hot Melt Extruded Abuse Deterrent
`Pellets Utilizing Design of Experiments (DOE). The AAPS Journal. 14(S2), Chicago, IL
`(2012).
`
`Page 11 of 25
`
`

`

`30. S. Maddineni, S.N. Murthy, S. Majumdar, M.A. Repka. Development of a Highly Drug
`Loaded Coenzyme Q10 - Lipid Matrix for Sustained Delivery Utilizing Hot Melt
`Extrusion. The AAPS Journal. 14(S2), Chicago, IL (2012).
`31. M. Pimparade, J. Lu, Sejal Shah, S. Majumdar, M.Rahman, Zh. Lian, D. Tewari, V. Bi, T.
`Durig, M.A. Repka. Development of Pediatric and Geriatric Taste Masked Formulations
`by Hot Melt Extrusion Techniques. The AAPS Journal. 14(S2), Chicago, IL (2012).
`32. M. Pimparade, S. Alshahrani, B. Alsulays, S. Shah, S. Majumdar, K. Kolter, N. Langley,
`M.A Repka. Compatibility and Intermolecular Interactions of Melt Extruded APIs with
`Polymeric Blends. The AAPS Journal. 14(S2), Chicago, IL (2012).
`33. X. Feng, S. Shah, S. Majumdar, M. Rahman, Zh. Lian, D. Tewari, V. Bi, T. Durig, M.A.
`Repka. Remodeled Recrystallization Kinetics to Predict the Physical Stability of
`Polymeric Amorphous Solid Dispersions. The AAPS Journal. 14(S2), Chicago, IL (2012).
`34. S. Alshahrani, B. Alsulays, S. Alshehri, S. Shah, S. Majumdar, K. Kolter, N. Langley,
`M.A. Repka. Improving the Solubility and Physical Stability of Carbamazepine using Hot
`Melt Extrusion. The AAPS Journal. 14(S2), Chicago, IL (2012).
`35. S. Alshahrani, B. Alsulays, M. Pimparade, S. Shah, S. Majumdar, K. Kolter, N. Langley,
`M.A. Repka. Characterization of Polymer-drug Interactions during Melt Extrusion
`Processes. The AAPS Journal. 14(S2), Chicago, IL (2012).
`36. B. Alsulays, S. Alshahrani, M. Pimparade, S. Shah, S. Majumdar, K. Kolter, N. Langley,
`M.A. Repka. Characterization of molecular interactions of Carbamezepine, Clotrimazole
`and Fenofibrate with Kollidon® VA 64 using Hot Melt Extrusion
`37. A.S. Alshetaili, E.A. Ashour, B.K. Almutairy, S. Shah, S. Majumdar, M.A. Repka.
`Evaluation of the Physico-mechanical Characteristics of Pellets of Different Polymer
`Prepared by Melt Extrusion/ Face-cut Pelletization. The AAPS Journal. 14(S2), Chicago,
`IL (2012).
`38. A.S. Alshetaili, E.A. Ashour, B.K. Almutairy, S. Shah, S. Majumdar, M.A. Repka.
`Formulation and Evaluation of Taste Masked Ketoprofen Pellets Prepared by Melt
`Extrusion/ Face-cut Pelletization. The AAPS Journal. 14(S2), Chicago, IL (2012).
`39. J. Lu, S. Shah, S. Majumdar, K. Kolter, N. Langley, M.A. Repka. The Utility of
`Lutrol®F127 as a Matrix Carrier for Solid Dispersions of Carbamazepine. The AAPS
`Journal. 14(S2), Chicago, IL (2012).
`40. J. Lu, S. Shah, A. Singh, S. Jo, S. Majumdar, K. Kolter, N. Langley, M.A. Repka. Thermal
`Analysis of the Miscibility of Soluplus®-felodipine Solid Dispersions. The AAPS
`Journal. 14(S2), Chicago, IL (2012).
`41. J. Lu, S. Shah, A. Singh, S. Jo, S. Majumdar, K. Kolter, N. Langley, M.A. Repka.
`Dissolution Behavior of Soluplus®-felodipine Solid Dispersions. The AAPS
`Journal. 14(S2), Chicago, IL (2012).
`42. S. Alshehri, S. Alshahrani, B. Almutairy, S. Shah, S. Majumdar, M.A. Repka.
`Development and Evaluation of Taste-masked Formulations of Mefenamic Acid using Hot
`Melt Extrusion Techniques. The AAPS Journal. 14(S2), Chicago, IL (2012).
`43. E. Ashour, S. Shah, S. Majumdar, M. Rahman, Zh. Lian, D. Tewari, V. Bi, T. Durig, M.A.
`Repka. Effect of Supercritical Carbon Dioxide on Hot Melt Extruded Cellulose Polymers,
`
`Page 12 of 25
`
`

`

`Hydroxypropylcellulose and Ethyl Cellulose. The AAPS Journal. 14(S2), Chicago, IL
`(2012).
`44. B. K. Almutairy, A. S. Alshetaili, S. M. Alshehri, S. Shah, S. Majumdar, M.A. Repka.
`Development and Characterization of Taste Masked Acetaminophen Tablets with Ethyl
`Cellulose ECN7 and Klucel™ Utilizing Hot Melt Extrusion. The AAPS Journal. 14(S2),
`Chicago, IL (2012).
`45. J. Morott, S. Shah, S. Majumdar, M. Rahman, Zh. Lian, D. Tewari, V. Bi, T. Durig, M.A.
`Repka. Development and Characterization of Taste Masked Hot Melt Extruded
`Formulations Containing Sildenafil Citrate. The AAPS Journal. 14(S2), Chicago, IL
`(2012).
`46. Ramesh Srirangam, Ketan Hippalgoankar, Bharathi Avula, Ikhlas A Khan and Soumyajit
`Majumdar. Ocular delivery of hesperidin and hesperetin following topical administration.
`AAPS Annual Meeting and Exposition, Washington DC, October, 2011
`47. Tushar Hingorani, Waseem Gul, Mahmoud ElSohly, Michael A. Repka and Soumyajit
`of Δ9-
`Majumdar. Transcorneal Permeability
`of Amino Acid Prodrugs
`Tetrahydrocannabinol. AAPS Annual Meeting and Exposition, Washington DC, October,
`2011
`48. Tushar Hingorani, Waseem Gul, Mahmoud ElSohly, Michael A. Repka and Soumyajit
`Majumdar. Influence of Surfactants and Ion Pair Complex Formation on Transcorneal
`Permeability of an Ionized Dicarboxylic Acid Prodrug. AAPS Ann