Dictionary -- STATlRef Online Medical Database
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`CYAN EXHIBIT 1040
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`v~uumn~a~-
`fiSTEflMAN'S
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`-
`
`Front Matter
`Title Page
`Copyright Page
`Preface
`New in This Edition
`Continuing Features
`Acknowledgements
`Your Medical Word Resource Publisher
`Consultants
`How to Use This Dictionary
`Organization of the Vocabulary
`Alpha betization
`Exceptions
`Subentries
`Spelling
`Subentries
`Cross-References
`Eponyms
`Abbreviations and Symbols
`Conventions
`Pronunciation Key
`Organization
`Prefixes and Suffixes
`
`N-<><§<C—IU1?U¢O'°OZZ'_7<‘—‘HIQTIITIUOUU)>
`
`Appendices
`Pronunciation
`
`<1 STEDMAN'S MEDICAL DICTIONARY — 28th Ed. (2006)
`
`A
`
`Front Matter
`
`Title Page
`Stedman's Medical Dictionary
`28th Edition
`
`931mmThe Best Words in Medicine,"
`
`
`
`
`yr:
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`'.
`
`.'.'I..-
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`Philadelphia - Baltimore - New York - London Buenos Aires - Hong Kong - Sydney - Tokyo
`
`Copyright Page
`Publisher: Julie K. Stegrnan
`SeniorProductManager: Eric Branger
`Associate Managing Editor: Tiffany Piper
`MarketingManager: Yvonne Palmer
`New Terms Editor: Thomas W. Filardo, MD
`Etymology Editor: John H. Dirckx, MD
`ChiefCopyeditor: Raymond Lukens
`Copyeditors: Ellen Atwood, Vincent Ercolano, Ellen Erkess, Linda Searing
`Pronunciations Editor: William R. Hensyl
`On-Line Editors: Barbara L. Ferretti, Kathryn J. Cadle, Lisa Fahnestock
`Proofreaders: Richard Diarnanti, Raymond Lukens, Kristi Lukens, Jeff Prucher, Linda C. Robbian
`Database Programmers: Dave Marcus, Lexi-Comp lnc., Hudson, OH
`Art Director: Jennifer Clements
`Illustrations: Neil O. Hardy
`Additional artwork by: Mary Anna Barratt Dimes, Kathryn Born, Rob Duckwall, Timothy Hengst, Mikki Senkarik, Michael Schenk, Larry Ward
`Graphic Artist: Susan Caldwell
`Typographic Design: Parkton Art Studio, Inc.
`
`Co yright © 2006
`Lippincott Williams & Wilkins
`A Wolters Kluwer Health Company
`35 West Camden Street
`Ba timore, Maryland 21201-2436 USA
`www.stedmans.com
`stedrnans @lwwwcom
`
`Co yright © by William Wood and Company: 1911, lsted.', 1912, 2nd ed.', 1914, 34 ed.', 1916, 4th ed.', 1918, 5th ed.', 1920, 6th ed.', 1922, 7th ed.',
`1924, 8th ed.', 1926, 9th ed.',1928, 10th ed.', 1930,1131 ed.
`
`Co yright © by Williams & Wilkins: 1933,12th ed', 1935, 13th ed.', 1939, 14th ed.', 1942, 15th ed.',1946,16th ed.',1949,17th ed.', 1953, 18th ed.',
`1957, 19th ed.', 1961, 20th ed.', 1966, 2lst ed.', 1972, 22nd ed.', 1976, 23rd ed.', 1982, 24th ed.', 1990, 25th ed.', 1995, 26th ed.
`
`
`
`Co yright © by Lippincott Williams & Wilkins: 2000, 27th ed.
`
`All rights reserved. This book and software are protected by copyright. No part of this book or software may be reproduced or transmitted in any form
`or y any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without
`written permission from the copyright owner.
`
`Stedman's, STEDMAN'S is a registered trademark of Lippincott Williams & Wilkins.
`Disclaimer
`The publisher is not responsible (as a matter of product liability, negligence or otherwise) for any injury resulting from any material contained herein.
`This publication contains information relating to general principles of medical care which should not be construed as specific instructions for individual
`patients. Manufacturers' product information and package inserts should be reviewed for current information, including contraindications, dosages and
`precautions.
`
`Library of Congress Cataloging-in—Publication Data
`Stedrnan, Thomas Lathrop, 1853-1938.
`Stedman's medical dictionary. i28th ed.
`p.
`',cm.
`Includes bibliographical references and index.
`ISBN-13: 978-0-7817-3390-8
`ISBN-10: 0-7817-3390-9
`1. Medicine--Dictionaries. I. Title. 11. Title: Medical dictionary.
`[DNLM: 1. Medicine--Dictionary--English. W 13 S812m 2006]
`R121.S8 2006
`610'.3--dc22
`
`2005021544
`
`ISBN-13: 978-0-7817-3390-8
`ISBN-10: 0-7817-3390-9
`
`Preface
`
`Welcome to the 28th edition of Stedman’sMedical Dictionary. This edition continues the long-standing tradition of a quality medical terminology
`reference that you have come to expect from Stedman's.
`
`v
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`Dictionary -- STATlRef Online Medical Database
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`smiliiiiiiii's
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`WMIMMMJ
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`l9 Results
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`STEDMAN'S MEDICAL DI" - (tret) To manage a disease by medicinal, surgical, or other measures; to care for
`Front Matter
`a patient medically or surgically. [Fr Waiter, fr. L. tracto, to drag, handle, perform]
`Title Page
`Copyright Page
`, Preface
`New in This Edition
`
`Copyright © 2006 Wolters Kluwer Health, Lippincott, Williams & Wilkins. All rights
`reserved.
`
`(+/—) Show / Hide Bibliography
`
`C°”“””i”9 Feature
`Acknowledgements
`Your Medical Word
`Consultants
`, How to Use This Dict
`
`Organization of the
`Alphabetization
`Exceptions
`Subentries
`
`Spelling
`Subentries
`Cross- References
`
`Eponyms
`Abbreviations and 1
`Conventions
`
`Pronunciation Key
`Organization
`Prefixes and SuffiXi
`
`\—lU7?UrO'UOZZ'_7?‘—'HICDT||T|UOUJJ>
`
`/ e, e — talalgia
`, talar — tastant
`, taste — tel-
`
`, tel- — tenascin
`i
`i-nnrlnr — i-nrhiiim (Tl
`)
`
`v
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`(
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`Dictionary -- STATlRef Online Medical Database
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`sutnmm's
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`moo-imam.-
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`Search: damage
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`l9 Results
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`a
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`STEDMAN'S MEDICAL DI" - (dam’ij) Harm, diminutiom or destruction of an organ, body part, system, or
`Fr°_nt Matter
`function. [M.E., fr. O.Fr., fr. L. damnum, loss, harm]
`T't'e Page
`diffuse alveolar damage. SYN: adult respiratory distress syndrome.
`Copyright Page
`‘ Preface
`New in This Edition
`
`Copyright © 2006 Wolters Kluwer Health, Lippincott, Williams & Wilkins. All rights
`reserved.
`
`
`(+/—) Show / Hide Bibliography
`
`Continuing Feature
`
`ACknow'edgementS
`Your Medical Word
`Consultants
`‘ How to Use This Dict
`
`Organization of the
`Alphabetization
`Exceptions
`Subentries
`
`Spelling
`Subentries
`Cross- References
`
`Eponyms
`Abbreviations and 1
`Conventions
`
`Pronunciation Key
`Organization
`Prefixes and SuffiXI
`
`0003}
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`\ '
`
`\'\
`
`‘ A — Darkschewitsch
`
`Da
`
`dA, dAdo
`da
`Daae
`DAB
`
`dacry-
`dacryadenitis
`dacryo-, dacry-
`dacryoadenitis
`dacryoblennorrhea
`dacryocele
`darn/nr‘vcf
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`v
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`fiSTEDMAN'S
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`mmrmmumw,-
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`3‘ Results
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`STEDMAN'S MEDICAL DI" - (in’jur-e) 1. The damage or wound of trauma. 2. Lesion (q.v.). [L. injuria, fr.
`Front Matter
`in- neg. +jus mm), right]
`blast injury. tearing of lung tissue or mpture of any tissue or organ without external
`injury, as by the force of an explosion.
`brachial plexus injury. in obstetrics, damage to the brachial plexus related to delivery;
`associated with excessive lateral stretching of the head, typically in cases of shoulder
`dystocia or breech deliveries. SEE ALSO: brachial birth palsy.
`closed head injury. a head injury in which continuity of the scalp and mucous membranes
`is maintained.
`.
`~
`~
`.
`contrecoup injury of brain. an injury occurring beneath the skull opposrte to the area of
`impact. _
`_
`.
`.
`.
`.
`-
`coup injury of brain. an injury occurring directly beneath the skull at the area of impact.
`degloving injury. an injury most commonly to an extremity or digit in which the skin and
`subcutaneous tissue are separated from the deeper tissue layers thereby depleting its blood
`.
`.
`.
`.
`.
`supply and increasmg the risk of tissue necros1s.
`egg-white injury. SYN: egg-white syndrome.
`flexion-extension injury. forceful sequential application of a forward and backward
`movement of the unsupported head that may produce an injury to the cervical spine or the
`brain.
`
`Title Page
`Copyright Page
`Preface
`New in This Edition
`Continuing Feature
`Acknowledgements
`Your Medical Word
`Consultants
`How to Use This Dict
`Organization of the
`Alphabetization
`Exceptions
`_
`SUbe_ntr'eS
`Spelling
`SUbentries
`Cross- References
`
`hyperextension-hyperflexion injury. violence to the body causing the unsupported head
`to move rapidly backward and forward, resulting in hyperextension and hyperflexion of
`the neck; does not imply any specific resultant trauma or pathology.
`injury of intervertebral disc. SEE traumatic cervical discopathy.
`open head injury. a head injury in which there is a loss of continuity of scalp or mucous
`membranes; the term is sometimes used to indicate a communication between the exterior
`and the intracranial cavity. SEE ALSO: penetrating wound.
`pneumatic tire injury. separation of the skin and subcutaneous tissue from the underlying
`fascia, classically occurring when an extremity is cmshed and rolled over by the tire of a
`vehicle; however, it may be incurred through other mechanisms that produce shear forces;
`similar to a degloving injury, except that the skin and subcutaneous tissue layers remain in
`continuity.
`reperfu sion injury. myocardial impairment, usually with arrhythmia, following the
`opening of arterial blockage and considered to be due to oxygen-derived free radicals.
`steering wheel injury. trauma to the anterior chest wall caused by impact with the steering
`wheel during an automobile accident; may include fractured sternum and ribs, cardiac
`contusion, tear of the aorta or other great vessels, as well as lung injuries.
`transfusion-related acute lung injury. adult respiratory distress syndrome (ARDS)
`occurring within 4 hours of transfusion. The estimated frequency is 1 in 5000 transfusions
`and the mechanism remains poorly understood. The prognosis is much better than with
`most other cases of ARDS. SEE ALSO: adult respiratory distress syndrome.
`whiplash injury. popular term for flexion—extension injury.
`
`Copyright © 2006 Wolters Kluwer Health, Lippincott, Williams & Wilkins. All rights
`reserved.
`
`(+/-) Show / Hide Bibliography
`
`Eponyms
`Abbreviations and 1
`Conventions
`Pronunciation Key
`Organization
`Prefixes and Suffix,
`
`0003}
`
`_
`A — Darkschewntsch
`
`A
`D
`2:4'D
`d
`d-
`D-
`-d
`DA
`D a
`dA, dAdo
`da
`
`Daae
`DAB
`dacry-
`dacryadenitis
`dacryo-, dacry-
`dacryoadenitis
`dacryoblennorrhea
`dacryocele
`darn/nr‘vcf
`
`v
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`Dictionary -- STATlRef Online Medical Database
`
`Page 1 of 1
`
`9 STEDMAN'S
`
`mmrminnmw,-
`
`STEDMAN'S MEDICAL DIA
`Front Matter
`
`Title Page
`Copyright Page
`Preface
`New in This Edition
`
`Continuing Feature
`Acknowledgements
`Your Medical Word
`Consultants
`How to Use This Dict
`
`Organization of the
`Alphabetization
`Exceptions
`Subentries
`
`Spelling
`Subentries
`Cross- References
`
`Eponyms
`Abbreviations and 1
`Conventions
`
`Pronunciation Key
`Organization
`Prefixes and SuffiXI
`
`A — Darkschewitsch
`
`Darling — decapsulai
`decarbonization — dc
`
`degenerate — democ
`demography — deox
`2-deoxycoformycin —
`dermatofibrosarcome
`desmoid — dextrad
`
`dextral — dialysate
`dialysis — dicentric
`dicephalous — diffra<
`diffusate — di|| oil
`
`diluent — diphtheric
`diphtheroid — disflue
`diphtheroid
`diphtherotoxin
`diphyllobothriasis
`Diphy/lobothrium
`diphyodont
`diplacusis
`rlinlnnia
`
`)
`
`0003}
`
`Search: disease
`
`3‘ Results
`
`- (di-zéz’) 1. An interruption, cessation, or disorder of a body, system, or
`organ structure or function. SYN: illness, morbus, sickness. 2. A morbid entity
`ordinarily characterized by two or more of the following criteria: recognized etiologic
`agent(s), identifiable group of signs and symptoms, or consistent anatomic alterations.
`SEE ALSO: syndrome. [Eng dis— priv. + ease]
`aaa disease. endemic anemia of ancient Egypt, ascribed in the Papyms Ebers to
`intestinal infestation with ancylostoma; now called ancylostomiasis.
`ABO hemolytic disease of the newborn. erythroblastosis fetalis resulting from
`matemal-fetal incompatibility with respect to an antigen of the ABO blood group; the
`fetus possesses A or B antigen (or both), that is lacking in the mother, and the mother
`produces immune antibody, that causes hemolysis of fetal erythrocytes.
`accumulation disease. a disease characterized by abnormal accumulation of a metabolic
`product in certain cells and tissues; examples include the mucopolysaccharidoses and
`lipoidoses.
`Acosta disease. (ah-kos’ta) SYN: altitude sickness.
`Adams-Stokes disease. (a’damz-stdks) SYN: Adams-Stokes syndrome.
`adaptation diseases. diseases falling theoretically into the Selye concept of the general-
`adaptation syndrome. The courses of these diseases lay within the organism's excessive
`and prolonged or deficient (i.e., maladaptive) responses to stressors. SEE ALSO:
`adaptation syndrome of Selye.
`Addison disease. (ad’i-son) SYN: chronic adrenocortical insufficiency.
`Addison-Biermer disease. (ad’i-son bEr’mér) SYN: pernicious anemia.
`akamushi disease. SYN: tsutsugamushi disease.
`Albers-Schonberg disease. (ahl’berz shém’bérg) SYN: osteopetrosis.
`Albright disease. (al’bth) SYN: McCune-Albright syndrome.
`Alexander disease [MIM*203450]. (al-ek-zan’dér) a rare, fatal degenerative disease of
`the central nervous system of infants, characterized by psychomotor retardation,
`seizures, and paralysis; megaloencephaly is associated with widespread leukodystrophic
`changes, especially in the frontal lobes.
`Almeida disease. (ahl-ma’da) SYN: paracoccidioidomycosis.
`Alpers disease. (al’pérz) SYN: poliodystrophia cerebri progressiva infantilis.
`alpha chain disease. a heavy chain disease that has monoclonal serum-urine
`immunoglobulin component that contains only Oi chain fragments but no light chain.
`May occur in a spectrum of plasmacytoses ranging from plasma cell hyperplasia to
`plasma cell myeloma.
`altitude disease. SYN: altitude sickness.
`
`Alzheimer disease (AD) flVHM’l‘104300]. (awlts’hi—mér) a progressive degenerative
`disease of the brain that causes impairment of memory and dementia manifested by
`confusion, visual-spatial disorientation, impairment of language function progressing
`from anomia to fluent aphasia, inability to calculate, and deterioration ofjudgment;
`delusions and hallucinations may occur. The most common degenerative brain disorder,
`AD makes up 70% of all cases of dementia. Onset is usually in late middle life, and
`death typically ensues in 5-10 years. SYN: Alzheimer dementia, presenile dementia (2),
`dementia presenilis, primary senile dementia.
`
`In 1906 the German neurologist Alois Alzheimer reported a case of presenile dementia
`in a 51-year-old woman whose brain showed distinctive changes at autopsy, but the high
`prevalence of this disorder went unrecognized until the later decades of the 20th century.
`Alzheimer disease (AD) currently ranks fourth as a cause of death in the US. Its
`estimated prevalence in this country is 2.5-4 million, with 360,000 new cases yearly, and
`its annual cost to the national economy is $7 5-100 billion. The lifetime risk of
`',,11 ~,,J,
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`developing AD is about 9%. Women are 1.5 times as likely as men to be affected. Onset V
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