throbber
Case 3:14-cv-05499-PGS-LHG Document 42-1 Filed 07/07/15 Page 1 of 5 PageID: 582
`
`Stephen M. Orlofsky
`David C. Kistler
`New Jersey Resident Partners
`BLANK ROME LLP
`301 Carnegie Center, 3d Floor
`Princeton, NJ 08540
`Telephone: (609) 750-7700
`
`William C. Jackson
`BOIES, SCHILLER & FLEXNER LLP
`5301 Wisconsin Ave, NW
`Washington, DC 20015
`
`Douglas Carsten
`WILSON SONSINI GOODRICH & ROSATI
`12235 El Camino Real
`Suite 200
`San Diego, CA 92130
`
`
`IN THE UNITED STATES DISTRICT COURT
`FOR THE DISTRICT OF NEW JERSEY
`
`
`
`Civil Action No. 3:14-cv-5499
`(PGS)(LHG)
`
`
`
`DECLARATION OF ROBERT
`DELAFIELD IN SUPPORT OF
`PLAINTIFF’S OPENING CLAIM
`CONSTRUCTION BRIEF
`
`
`
`
`
`UNITED THERAPEUTICS
`CORPORATION,
`
`Plaintiff,
`
`
`
`
`v.
`
`
`
`SANDOZ, INC.,
`
`Defendant.
`
`
`
`
`
`
`
`
`
`
`
`

`
`Case 3:14-cv-05499-PGS-LHG Document 42-1 Filed 07/07/15 Page 2 of 5 PageID: 583
`
`I, Robert A. Delafield II, declare the following:
`
`1.
`
`I am an attorney at Wilson Sonsini Goodrich & Rosati, counsel to Plaintiff United
`
`Therapeutics Corporation (“United Therapeutics”). I submit this Declaration in support of United
`
`Therapeutics’ Opening Claim Construction Brief.
`
`2.
`
`Attached hereto as Exhibit 1 is a true and correct copy of U.S. Patent No. 8,497,393,
`
`bearing Bates numbers UTC_REM_II_000003353 – UTC_REM_II_000003369.
`
`3.
`
`Attached hereto as Exhibit 2 is a true and correct copy of an excerpt from Zumdahl,
`
`Chemistry, p. A26 (1986), bearing Bates numbers UTC_REM_II_000001645 –
`
`UTC_REM_II_000001647.
`
`4.
`
`Attached hereto as Exhibit 3 is a true and correct copy of an excerpt from Aulton,
`
`Aulton’s Pharmaceutics: The Design and Manufacture of Medicines, pp. 338-341 (3rd ed. 2007),
`
`bearing Bates numbers UTC_REM_II_000001755 – UTC_REM_II_000001758.
`
`5.
`
`Attached hereto as Exhibit 4 is a true and correct copy of an excerpt from Richet, The
`
`Physical Basis of Thermodynamics with Application to Chemistry, pp. 285-286 (2001), bearing
`
`Bates numbers UTC_REM_II_000005495 – UTC_REM_II_000005498.
`
`6.
`
`Attached hereto as Exhibit 5 is a true and correct copy of an excerpt from Brown, et
`
`al., Chemistry: The Central Science, p. G-1 (9th ed. 2003), bearing Bates numbers
`
`UTC_REM_II_000001584 – UTC_REM_II_000001586.
`
`7.
`
`Attached hereto as Exhibit 6 is a true and correct copy of an excerpt from March, et
`
`al., March’s Advanced Organic Chemistry, pp. 327-332 (5th ed. 2001), bearing Bates numbers
`
`UTC_REM_II_000001587 – UTC_REM_II_000001594.
`
`
`
`-2-
`
`

`
`Case 3:14-cv-05499-PGS-LHG Document 42-1 Filed 07/07/15 Page 3 of 5 PageID: 584
`
`8.
`
`Attached hereto as Exhibit 7 is a true and correct copy of an excerpt from Rayner-
`
`Canham, et al., Descriptive Inorganic Chemistry, pp. 121-134 (2nd ed. 1996), bearing Bates
`
`numbers UTC_REM_II_000001595 – UTC_REM_II_000001610.
`
`9.
`
`Attached hereto as Exhibit 8 is a true and correct copy of an excerpt from Loudon, et
`
`al., Organic Chemistry, pp. 87-112 (3rd ed. 1995), bearing Bates numbers
`
`UTC_REM_II_000001611 – UTC_REM_II_000001638.
`
`10.
`
`Attached hereto as Exhibit 9 is a true and correct copy of an excerpt from Bettelheim,
`
`et al., Introduction to General, Organic & Biochemistry, p. G-2 (6th ed. 2001), bearing Bates
`
`numbers UTC_REM_II_000001639 – UTC_REM_II_000001641.
`
`11.
`
`Attached hereto as Exhibit 10 is a true and correct copy of an excerpt from Suchocki,
`
`et al., Conceptual Chemistry, p. G-1 (2001), bearing Bates numbers UTC_REM_II_000001642 –
`
`UTC_REM_II_000001644.
`
`12.
`
`Attached hereto as Exhibit 11 is a true and correct copy of file history for U.S. Patent
`
`No. 8,497,393, bearing Bates numbers UTC_REM_II_000003371 – UTC_REM_II_000003575.
`
`13.
`
`Attached hereto as Exhibit 12 is a true and correct copy of an excerpt from Zumdahl,
`
`Chemistry, pp. A25, A36 (1986), bearing Bates numbers UTC_REM_II_000001763 –
`
`UTC_REM_II_000001766.
`
`14.
`
`Attached hereto as Exhibit 13 is a true and correct copy of an excerpt from Brown, et
`
`al., Chemistry: The Central Science, pp. G-2, G-10 (9th ed. 2003), bearing Bates numbers
`
`UTC_REM_II_000001759 – UTC_REM_II_000001762.
`
`15.
`
`Attached hereto as Exhibit 14 is a true and correct copy of an excerpt from Webster’s
`
`New Collegiate Dictionary, pp. 29, 901, 910-911 (Springfield, MA, G. & C. Merriam Co. 1981),
`
`bearing Bates numbers UTC_REM_II_000001782 – UTC_REM_II_000001787.
`
`
`
`-3-
`
`

`
`Case 3:14-cv-05499-PGS-LHG Document 42-1 Filed 07/07/15 Page 4 of 5 PageID: 585
`
`16.
`
`Attached hereto as Exhibit 15 is a true and correct copy of an excerpt from Suchocki,
`
`et al., Conceptual Chemistry, p. G-6 (2001), bearing Bates numbers UTC_REM_II_000001767 –
`
`UTC_REM_II_000001769.
`
`17.
`
`Attached hereto as Exhibit 16 is a true and correct copy of Williams, et.al.,
`
`“Asymmetric, Stereocontrolled Total Synthesis of Paraherquamide A,” J. Am. Chem. Soc.,
`
`125:12172-178 (2003), bearing Bates numbers UTC_REM_II_000001741 –
`
`UTC_REM_II_000001747.
`
`18.
`
`Attached hereto as Exhibit 17 is a true and correct copy of Williams, et.al.,
`
`“Stereocontrolled Total Synthesis of (+)-Paraherquamide B”, J. Am. Chem. Soc., 118:557-579
`
`(1996), bearing Bates numbers UTC_REM_II_000001718 – UTC_REM_II_000001740.
`
`19.
`
`Attached hereto as Exhibit 18 is a true and correct copy of Williams, et.al., “Synthetic
`
`Studies on Et-743. Assembly of the Pentacyclic Core and a Formal Total Synthesis,” J. Org.
`
`Chem., 73(24):9594-9600 (2008), bearing Bates numbers UTC_REM_II_000001748 –
`
`UTC_REM_II_000001754.
`
`20.
`
`Attached hereto as Exhibit 19 is a true and correct copy of Heathcock, et.al., “Further
`
`Studies of the Daphniphyllum Alkaloid Polycyclization Cascade,” J. Org. Chem., 66:450-454
`
`(2001), bearing Bates numbers UTC_REM_II_000001670 – UTC_REM_II_000001689.
`
`21.
`
`Attached hereto as Exhibit 20 is a true and correct copy of Heathcock, et.al.,
`
`“Daphniphyllum Alkaloids. 12. A Proposed Biosynthesis of the Pentacyclic Skeleton. Proto-
`
`Daphniphylline,” J. Org. Chem., 57:2554-2566 (1992), bearing Bates numbers
`
`UTC_REM_II_000001657 – UTC_REM_II_000001669.
`
`
`
`-4-
`
`

`
`Case 3:14-cv-05499-PGS-LHG Document 42-1 Filed 07/07/15 Page 5 of 5 PageID: 586
`
`22.
`
`Attached hereto as Exhibit 21 is a true and correct copy of Buchwald, et.al., “An Air-
`
`Stable Catalyst System for the Conversion of Esters to Alcohols,” J. Org. Chem., 57:3753-3755
`
`(1992), bearing Bates numbers UTC_REM_II_000001648 – UTC_REM_II_000001650.
`
`23.
`
`Attached hereto as Exhibit 22 is a true and correct copy of Buchwald, et.al., “A
`
`Practical Titanium-Catalyzed Synthesis of Bicyclic Cyclopentenones and Allylic Amines,” J.
`
`Org. Chem., 61:2713-2718 (1996), bearing Bates numbers UTC_REM_II_000001651 –
`
`UTC_REM_II_000001656.
`
`24.
`
`Attached hereto as Exhibit 23 is a true and correct copy of an excerpt from Hawley’s
`
`Condensed Chemical Dictionary, pp. 34, 221 (14th ed. 2001), bearing Bates numbers
`
`UTC_REM_II_000001770 – UTC_REM_II_000001774.
`
`25.
`
`Attached hereto as Exhibit 24 is a true and correct copy of an excerpt from Loudon, et
`
`al., Organic Chemistry, pp. 454-455 (3rd ed. 1995), bearing Bates numbers
`
`UTC_REM_II_000001700 – UTC_REM_II_000001703.
`
`I declare under penalty of perjury under the laws of the United States of America that the
`
`foregoing is true and correct.
`
`Executed this 7th day of July, in Austin, Texas.
`
`
`
`
`
`
` Robert A. Delafield II
`
`
`
`-5-

This document is available on Docket Alarm but you must sign up to view it.


Or .

Accessing this document will incur an additional charge of $.

After purchase, you can access this document again without charge.

Accept $ Charge
throbber

Still Working On It

This document is taking longer than usual to download. This can happen if we need to contact the court directly to obtain the document and their servers are running slowly.

Give it another minute or two to complete, and then try the refresh button.

throbber

A few More Minutes ... Still Working

It can take up to 5 minutes for us to download a document if the court servers are running slowly.

Thank you for your continued patience.

This document could not be displayed.

We could not find this document within its docket. Please go back to the docket page and check the link. If that does not work, go back to the docket and refresh it to pull the newest information.

Your account does not support viewing this document.

You need a Paid Account to view this document. Click here to change your account type.

Your account does not support viewing this document.

Set your membership status to view this document.

With a Docket Alarm membership, you'll get a whole lot more, including:

  • Up-to-date information for this case.
  • Email alerts whenever there is an update.
  • Full text search for other cases.
  • Get email alerts whenever a new case matches your search.

Become a Member

One Moment Please

The filing “” is large (MB) and is being downloaded.

Please refresh this page in a few minutes to see if the filing has been downloaded. The filing will also be emailed to you when the download completes.

Your document is on its way!

If you do not receive the document in five minutes, contact support at support@docketalarm.com.

Sealed Document

We are unable to display this document, it may be under a court ordered seal.

If you have proper credentials to access the file, you may proceed directly to the court's system using your government issued username and password.


Access Government Site

We are redirecting you
to a mobile optimized page.





Document Unreadable or Corrupt

Refresh this Document
Go to the Docket

We are unable to display this document.

Refresh this Document
Go to the Docket