Case: 1:16-cv-00651 Document #: 106-5 Filed: 05/08/18 Page 1 of 3 PageID #:3223
`Case: 1:16—cv—00651 Document #: 106-5 Filed: 05/08/18 Page 1 of 3 PageID #:3223
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`Case: 1:16—cv—00651 Document #: 106-5 Filed: 05/08/18 Page 1 of 3 PageID #:3223
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`EXHIBIT E
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`ABBOTT LICENSES NEW ANESTHESIA DRUG FROM ORION CORP. - Free Online Library
`Case: 1:16-cv-00651 Document #: 106-5 Filed: 05/08/18 Page 2 of 3 PageID #:3224
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`The Free Library > Business and Industry > Business > PR Newswire > October 26, 1994
`The Free Library > Communications > News, opinion and commentary > PR Newswire > October 26, 1994
`The Free Library > Date > 1994 > October > 26 > PR Newswire
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`ABBOTT LICENSES NEW ANESTHESIA DRUG FROM
`ORION CORP.
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` ABBOTT PARK, Ill., Oct. 26 /PRNewswire/ -- Abbott Laboratories (NYSE: ABT)
`has signed a licensing agreement with Orion Corp. (Espoo, Finland) for the
`rights to develop and market dexmedetomidine, an alpha- 2 agonist discovered
`by Orion. Alpha-2 agonists are a new class of drugs under investigation for
`the purpose of relieving physiological stress during and after surgery.
` Abbott has been granted exclusive worldwide rights for dexmedetomidine,
`with the exception of Scandinavia, where Orion retains exclusive rights.
`Both companies will manufacture finished product.
` Dexmedetomidine has been investigated by Orion Pharma, the pharmaceutical
`division of Orion Corp., as an anesthetic adjunct in clinical trials.
`Results of these studies indicate that dexmedetomidine may have unique
`characteristics which may benefit patients during and after surgery. It has
`been shown to stabilize hemodynamic responses to stressful stimuli during
`anesthesia and surgery. Dexmedetomidine also has been shown to decrease the
`amount of anesthetic and analgesic drugs needed during and after surgery.
`Preliminary studies also indicate that dexmedetomidine may reduce the
`incidence and severity of perioperative myocardial ischemia caused by
`surgical stress.
` "Dexmedetomidine will broaden Abbott's market-leading anesthesia product
`offering," said Irene Hrusovsky, M.D., worldwide venture head, Abbott
`Laboratories. "The drug's potential for control of the stress responses
`during and after surgery may reduce post-operative side effects and
`complications. We believe these attributes may ultimately reduce costs and
`improve patient outcomes."
` Abbott plans to conduct worldwide clinical trials which, if successful,
`would lead to regulatory filings beginning in late 1997.
` Orion Pharma is Finland's leading health care company. The company
`develops, manufactures and markets finished pharmaceutical products and bulk
`drugs. It has devoted research to anesthesia, neurology, cancer, cardiac
`insufficiency, asthma and treatment of post-menopausal symptoms.
` Abbott Laboratories is a world leader in anesthesia products. The company
`manufactures and markets a broad line of anesthesia drugs, drug delivery
`systems, pain management technologies and value-added disposables.
` Abbott Laboratories is a worldwide manufacturer of health care products,
`employing 50,000 people. In 1993, the company's sales and net earnings were
`$8.4 billion and $1.4 billion, respectively, with earnings per share of
`$1.69.
` -0- 10/26/94
` /CONTACT: Regina Lemke, Abbott Laboratories, 708-937-0822/
` (ABT)
`
`CO: Abbott Laboratories; Orion Corp. ST: Illinois IN: MTC SU:
`
`BN -- AT005 -- 1735 10/26/94 10:34 EDT
`
`COPYRIGHT 1994 PR Newswire Association LLC
`No portion of this article can be reproduced without the express written permission from the copyright holder.
`Copyright 1994 Gale, Cengage Learning. All rights reserved.
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`Publication: PR Newswire
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`Date: Oct 26, 1994
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`Words: 376
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`The Free Library > Business and Industry > Business > PR Newswire > October 26, 1994
`The Free Library > Communications > News, opinion and commentary > PR Newswire > October 26, 1994
`The Free Library > Date > 1994 > October > 26 > PR Newswire
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`ABBOTT LICENSES NEW ANESTHESIA DRUG FROM ORION CORP. - Free Online Library
`Case: 1:16-cv-00651 Document #: 106-5 Filed: 05/08/18 Page 3 of 3 PageID #:3225
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