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`NOTEBOOK NO,__/0 5.23
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`Page 12
`Page 12
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`
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`TITLE_~UDLtptttimmny 94 / 2 Q4%4 Book No. 4
`
`
`
`
`
`
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`Project No.
`*
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`Sami!
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`From Page No.__
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`Project No.___
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`Ee
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`Ca Dttnee,Matibed
`
`1fbj.test
`2.50
`
`0.35
`77
`70 PHE
`ALA
`0.55
`78
`71 THR
`SER
`0.44
`79
`72 LEU
`LEU
`0.64
`80
`73 THR
`ALA
`(2b. 2)
`74 TE 81
`The
`0.21
`75 SER
`82
`SER
`0.72
`76 SER
`83
`GLY
`0.73
`77 VAL
`84
`LEU
`0.74
`78 GLN
`865
`GLU
`0.88
`79 ALA
`86
`ALA
`0.80
`80 GLU
`87
`GLU
`0.85
`81 ASP
`88
`ASP
`1.15
`82 LEU
`69
`GLU
`0.70
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`90
`SER
`0.37
`84 VAL
`91
`ASP
`85 TYR
`92 0.38
`TYR
`86 TYR
`93
`0.28
`TYR
`87 CYS
`94
`0.37
`cyS
`88 GLN
`95
`0.80
`ALA
`89 ASN
`96
`1.48
`SER
`90 HIS
`98
`1.73
`TRP
`96 TYR 100
`1.26
`SER
`96 PRO 101
`2.29
`SER
`97 LEU 102
`1.35
`TYR
`998 THR 103
`1.51
`VAL
`99 PHE 104
`0.82
`PRE
`GLY 100 GLY 105
`1.38
`THR 101 GLY 105
`2.48
`THR 101 ALA 106
`1.56
`GLY 102 GLY 107
`0.81
`THR 103 THR 108
`0.66
`L¥S 104 LYS 109
`0.59
`VAL 105 LEU 110
`0.74
`THR 106 GLU 111
`0.92
`VAL 107 ILE 112
`1.26
`LEV 106 LYS1131.82
`
`.
`
`j
`
`t
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`From PDB files: 1fb4.test
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`112
`111
`anap . coat
`From PDB files: 1fb4.test
`1fb4
`1fbj
`2.50
`Maximum distance cutoff for CA-CA was
`Res
`NUMRES molecules 162
`112
`118
`Res Dist
`
`1fb4=2mep 0; Law 1 1.9
`Res
`Res Dist
`LEU 4 LEU
`4
`1.23
`SER
`64 SER
`64
`0.33
`GLU
`1 ASP
`L
`2.34
`THR’
`5 THR
`5
`0.93
`LYS
`65 GLY
`65 0.90
`VAL
`3 VAL
`3
`2.46
`GLN
`6 GLN
`6
`0.457
`SER
`66 SER
`66
`2.13
`LEU
`4 MET
`4
`0.30
`PRO
`7 SER
`7
`1.28
`THR
`68 THR
`68 0.85
`TH St
`5
`8.63
`PRO
`7 PRO
`8
`2.34
`SER
`69 SER
`69 0.96
`GLN
`6 GLN
`6
`0.74
`PRO
`8 ATA
`9
`0.68
`ALA
`70 TYR
`70 0.31
`PRO
`7 S8BR
`7
`1.80
`Gre
`9 ILE
`10
`1.37
`SER
`71 SER
`71 0.45
`PRO
`7 PRO
`86
`2.49
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`72 LEU
`72
`0.25
`PRO
`8 SER
`9
`0.93
`ae i a a ALA
`73 THR
`73
`0.45
`SER
`9 SER
`10
`1.08
`Sty
`iz MLA
`13
`0 Bb a os MOL
`ALA
`10 LEU
`11
`1.91
`THR
`13 SER
`14
`0.44
`SER
`75 ASN
`75
`1.03
`SER
`11 SER
`12
`2.48
`PRO.
`14 LEU
`15
`0.62
`GLY
`76 THR
`76
`0.52
`Gi¥
`i2 VAL
`13
`1.89
`GLY
`15 GLY
`16
`0.17
`LEU
`77 MET
`77
`0.69
`THR
`13 SER
`14
`1.68
`GIN;
`16 GIN 17
`0.30
`@w 78 cw 78
`0.75
`PRO
`14 ALA
`15
`1.05
`ARG: 17 LYS
`18
`0.25
`ALA
`79 ALA
`79 0.95
`Gly
`15 GLY
`le
`1.06
`VAL
`18 VAL
`19
`0.68
`GLU
`80 GLU
`80 0.61
`GLN
`16 GLU
`17
`1.12
`THR
`19 THR
`20
`0.85
`ASP
`81 ASP
`81
`1.24
`ARG
`17 ARG
`18
`0.91
`IZE'! 20 ILE
`21
`0.12
`GLU
`82 ALA
`82
`1.40
`VAL
`18 VAL
`19
`0.40
`SER!‘ 21 THR
`22
`0.46
`SER
`83 ALA
`83
`0.35
`THR
`|19 THR
`20
`0.47
`CySh 22 cys
`23
`0.28
`ASP
`84 ILE 84
`0.16
`TLE
`20 HEY
`21
`6.40
`THR’ 23 SER
`24
`0.99
`re OS TYR
`65
`0.23
`SER
`21 SER
`22
`0.18
`GLY
`24 ALA
`25
`0.37
`TYR
`86 TYR
`86
`0.54
`cra
`22 CYs
`323
`4.353
`THR
`25 SER
`26
`1.95
`cis
`87 CYS
`87
`0.56
`TER
`23 LYS
`24
`1.21
`THR
`25 SER
`27
`2.33
`ALA
`88 GLN
`68
`0.48
`GLY
`24 SER
`25
`0.64
`Gon
`26 SER
`27
`1.77
`SER
`89 GLN
`89
`0.53
`THR
`25 SER
`26
`2.16
`SER
`27 SER
`28
`2.44
`TRP
`90 TRP
`90
`1.58
`THR
`25 GIN 27
`2.49
`ILE
`30 SER
`30
`1.00
`AGN
`695 PRO
`93
`2.10
`GLY
`23 SER
`28
`1.67
`THR
`31 SER
`31
`1.47
`SER
`96 LEU
`94
`1.57
`THR
`31 ASN
`37
`2.18
`VAL
`32 LEU
`32
`1.00
`Tre:
`97 ILE 95
`0.62
`THR
`31 PHE
`38
`2.28
`ASN
`33 HIS
`33
`0.26
`VAL
`98 THR
`96
`0.70
`VAL
`32 LEU
`39
`1.41
`TRP
`34 TRP
`34
`0.47
`PHE
`99 PHE
`97
`0.64
`ASN
`33 ALA
`40
`0.73
`Wie
`35 Tn 35
`«0.59
`GLY 100 GLY
`98
`0.77
`PF 3 TRP
`41
`«0.37
`GLN
`36 GLN
`36
`0.38
`THR 101 ALA
`99
`1.18
`TYR
`35 TYR
`42
`0.30
`GLN
`37 GLN
`37
`0.41
`GLY 102 GLY 100
`0.67
`GLN
`36 GLN
`43
`0.35
`LEU
`38 LYS
`38
`2.15
`THR 103 THR 101
`0.23
`GLN
`37 GLN
`44
`0.31
`LEU
`38 SER
`39
`2.13
`LYS 104 LYS 102
`0.36
`ALA
`42 PRO 49
`0.56
`MET
`,41 THR
`41
`2.21
`VAL 105 LEU 103
`0.67
`FRO
`47 PRO
`59
`0.33
`BLA’ 42 SER
`42
`0.50
`THR 106 GLU 104
`1.08
`LYS
`44 LY8
`S51
`0.24
`PRO, 43 PRO
`43
`0.96
`VAL 107 LEU 105
`0.65
`LEU
`45 LEU
`52
`0.48
`LYS! 44 LYS
`44
`0.63
`LEU 108 LYS 106
`0.65
`LEU
`46 LEU
`53
`0.76
`LEU 45 PRO
`45
`0.83
`GLY 109 ARG 107
`2.30
`TLe
`47 Te $4
`0.56
`LEU 46 TRP
`46
`0.75
`TYR
`48 TYR
`55
`0.67
`De
`47 ILE 47.
`6.14
`Hl
`ARG
`49 GLY
`56
`0.79
`TYR
`48 TYR
`48
`06.51
`ASP
`50 ALA
`57
`0.67
`ARG
`49 GLU
`49
`1.61
`ALA
`51 SER
`58
`0.57
`Bee
`50 TLE
`50
`1.23
`Mer
`52 THR
`59 ©.59
`ALA
`51 SER
`51
`0.40
`ARG
`53 ARG
`60
`1.25
`MET
`52 LYS
`52
`0,74
`PRO
`54 GLU
`61
`1.43
`ARG
`53 LEU 53
`1.02
`eek
`3S See 62.7
`PRO
`54 ALA
`54
`2.21
`GLY
`56 GLY
`63
`1.01
`PRO
`54 SER
`55
`2.33
`iT ee
`SER
`55 SER
`55
`2.19
`PRO
`58 PRO
`65
`0.19
`Gly
`56 GLY
`56
`1.26
`THR
`59 ASP
`66
`0.24
`VAL
`57 VAL
`57
`1.16
`ARG
`60 ARG
`67
`0.48
`PRO
`58 PRO
`58
`0.92
`PHE
`61 PHE
`68
`0.22
`THR
`59 ALA
`59
`0.52
`SER
`62 THR
`69
`0.28
`ARG
`60 ARG
`60
`0.59
`GLY
`63 GLY
`70
`0.51
`PHE
`61 PHE
`61
`0.56
`BER
`64 SER
`71
`0.49
`SER 62 SER
`62
`0.33
`[YS
`65 GLY
`72 L.is
`é
`2 cS THR
`75
`1.01
`= oar
`4.5
`SER
`69 ASP
`76
`0.65
`:
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`77
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`ang HATCA prrgtem
`
`om ~
`
`Witnessed & Understood by me,
`
`Date
`
`Invented by
`
`Date
`
`Page 14
`Page 14
`
`To Page aad
`
`
`
`Recorded by
`
`
`
`Project No.
` Book No... 3
`
`
`TITLE
`
`From Page No.“
`
`1REI MOLECULE A
`2.50
`
`FODORPHOORPOPPrPOOODOOSOPHEHERPHEOOGOODOOOOSG
`
`SER
`
`1REI MOLECULE B
`2.50
`
`PRO
`
`GLU
`LEU
`THR
`GLN
`
`From PDB files: 1FB4. TEST
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`112
`107
`1FB4
`LREI
`Res
`Res Dist
`ASP
`.28
`MET
`81
`THR
`GLN
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`From PDB files: 1FB4.TEST
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`112
`107
`1FB4
`1LREI
`Res
`Res Dist
`ASP
`48
`MET
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`SOONSCSCSCOOSCOOCOPFPHOOOHOOOCOCOOOOOOOHRPNNKFOOODOOCOOHOPBENHONEKFOOOW
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`
`Witnessed & Understood by me,
`
`Page 15
`
`Invented by
`
`
`
`4
`
`rs
`
`Project No.
`Book No. ————srITLE
`
`
`
`rom Page No.= |
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`SERE PEST
`From PDB files: 1FB4.TEST
`2rhe.newrot
`From PDB files: 1fb4¢.test
`7 be
`ine
`2.50
`Maximum distance cutoff for CA-CA was
`shi
`2.50
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`112
`108
`NUMRES molecules 162
`112
`114
`
`
`
`lfb4 1FB4=3FAB 2rhe '
`Res
`Res Dist
`a
`Res
`Res Dist
`+
`—
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`oo eeaee a ie - aoae ce
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`
`
`me STR 5 0866@tlU 2 Oe — tsa. 5 oa SER 75 THR 75 0.94
`
`
`
`
`
`_ GIN
`6 GLN
`6
`0.14
`SER
`64 SER
`66
`0.34
`int
`Lee
`eo oe
`GLY
`76 GLY
`76
`1.39
`PRO
`7 PRO
`7
`0.31
`LYS
`65 LYS
`67
`0.16
`_— oo 7} a LEU
`77 LEU 77
`1.14
`= fo 68
`lB SER
`66 SER
`68
`0.36
`ee Gu 7a GIN 78
`0.36
`os
`
`= Jo fF OM—gr a7 GY 6S 0.15 a oe SF Bae ALA 79 ALA 79 0.43
`
`
`
`
`
`ALA
`10 ALA
`10
`0.74
`THR
`68 THR
`70
`0.19
`et oe ae Bae
`GLU
`80 GLU
`80
`0.69
`ee aaa oe |
`ALA
`“go
`4—
`«ASP
`681 ASP
`81
`(0.52
`wh
`GLX
`12 GLY
`12
`0.36
`MLA
`JO ALA
`7a
`0.14
`een
`11 Sen
`1)
`0.4
`GLU
`‘62 Gt
`82
`0.48
`a uS SS 6 oe ion 1) 6
`Sie | te
`SER
`83 ALA
`83
`0.25
`mm if PRO
`14 0.
`Lm 72 Lau
`74
`0.26 —
`mr 3 A 1) OE
`ASP
`84 ASP
`84
`0.39
`GLY
`15 GLY
`15
`0.64
`mA 73 ALA
`73
`0.31
`ig ac TYR
`85 TYR
`85
`0.18
`et
`GLN
`16 GLN
`16
`0.34
`os 4 ae we Bib
`GLY
`15 GLY
`15 1.12 GyR
`86 TYR
`86
`0.18
`ARG
`17 ARG
`17
`0.60
`SER
`75 SER
`77
`0.51
`po a age
`CYS
`87 CYS
`87
`0.30
`VAL
`18 VAL
`18
`0.52
`@x
`76 GLY
`7a
`1.01 i i,
`ee Le ee657
`THR
`19 THR
`19
`0.54
`LEU
`77 LEU 79
`0.65
`VEoe SER
`89 SER
`89
`0.64
`TLE
`20 ILE
`20
`0.07
`GLU
`78 GLU
`80
`0.46
`THR
`19 THR
`19
`0.79
`TRE
`90 TYR
`90
`0.95
`Sie 2 he
`BA ome Ol
`0.41
`ST fa tO OMe
`91 MP
`91
`0.59
`C¥S
`22
`CYS
`22
`0.
`GLU
`80 GLU
`82
`0.54
`@s 22s 2 0 a
`SER
`92 ARG
`92
`1.93
`=a eee oe ASP
`81 ASP
`83
`0.45
`ox io 2 on
`SER
`96 LEU
`94
`0.94
`1
`_ at co a oa
`GLU
`82 GLU
`84
`0.32
`ae as cee
`on ee |OUR O97 ARG
`95
`(0.38
`a SER
`83 ALA
`85
`0.25
`os ea as Oe
`VAL
`98 VAL
`98
`0.71
`
`
`
`
`
`
`-_— oe ASP ok ae|PME84 ASP 86 0.23 = is 3G cen 99 PR O99 (0.87
`
`an eae 36 TR 85 TYR
`87
`0.27
`oe 2] aim 27 ae
`GLY 100 GLy 100
`0.25
`2 2 oe
`TYR
`86 TYR
`88
`0.28
`eel
`fl feEe THR 101 GLY 101
`2.24
`‘
`CYS
`87 CYS
`89
`0.33
`'
`GLY 102 Giy 102
`1.65
`|
`GLY
`28 GLY
`30
`0.40 ae ILE,
`27BILE
`27B 0.62
`fn iii: sed jon eee
`2a fe
`SER
`89 ALA
`91
`0.20
`1 af
`oe 3 Se rc Oe «(RMS Los Lys 104
`0.41
`toe a5 ote
`TRE
`90 TRP
`92
`0.33
`ILE 30 ASN
`30
`0.59 |
`VAL 105 LEU 105
`0.37
`oe sean sa Gan
`ASN
`91 ASN
`93
`0.80
`= Ge iitxe f2
`0.@e [.
`THE LOS TER 106
`0.33
`a fue 2 @ER
`92 ASP
`94
`1.37
`i, sae Sh oe
`VAL 107 VAL 107
`0.30
`-— aes Se
`ASP
`94 SER
`95
`1.86
`ios 3 a fs
`fae ||108 Lay ise
`oo. 83
`‘
`ASP
`94 LEU
`96
`2.340
`5
`GLY 109 ARG 109
`2
`TYR
`35 TYR
`37
`0.49
`TRe
`34 TRE
`34
`0.79 [~
`+46
`ASN
`95 ASP
`97
`0.76
`oe Geek aa oe
`GLN110 GLN 110
`2.46
`|
`GLN
`36 GLN
`38
`0.68
`—_.—
`r
`SER
`96 GLU
`98
`1.74
`——
`—
`TYR
`97 PRO
`99
`0.50 a et
`GIN 36 GIN 36
`0.89 +—i— wenn
`GLN
`37 GLN
`39
`1.29
`LEU
`38 VAL
`40
`2.15
`VAL
`98 GLY 100
`0.56
`i
`37 GIN 37 0.|
`CLN
`
`
`
`
`
`
`
`GLY eeMB k= (ChaBRfe a LEU 38 LEU 1.82 Dad|ei tt40 PRO 41 1,91 38 ‘
`MET
`41 LYS
`43
`2.34
`pe Hn
`MET
`41 THR
`41
`1.88
`4
`f
`ALA
`42 LYS
`43
`2.35
`THR 101 GLY 103
`0.96
`as 42 MA te 1.
`ALA
`42 ALA
`44
`1.96
`GLY 102 GLY 104
`0.89 3-9 po an ee ee fr
`| a
`PRO
`43 PRO
`45
`1.31 EteeBe
`LYS
`44 LYS
`44 0.0 |
`|
`|
`LYS 44 LYS
`46
`0.89
`Fea S04 Lea the 60a
`ee Leo
`45 1 45 0.Ld
`eB
`LEU 45 LEU
`47
`0.77
`TA, 105 LM if? 0:30
`lev 46 LEU
`46
`1.0% |
`|
`|
`LEU 46 LEU
`48
`0.37 i 360 wen Soe
`a a4
`ARG
`53 PHE
`48
`2.02
`—~ Tr
`47 1s 49
`OL Re
`eM. 307 YA 109
`0093 aieee eee
`ited a
`TYR
`48 TYR
`50
`0.07
`:
`ARG
`60 ARG
`53
`0.20
`|
`LEU 108 LEU 110
`1.45
`
`
`mc 40Trm 51 04 1 aSSa PRE 61 PHE 61 0.17 |
`
`
`
`
`0.18 |
`1
`ASP
`50 ASN
`52
`0.52
`SER
`62 SER
`62
`ALA
`51 ASP
`53
`0.44 |
`GLY
`63 °VAL
`63
`0.lep.
`|
`MET
`52 LEU
`54
`0.46
`17.1) 0) CUT SER
`64 SER
`64
`0.83 —t—7——}-—_+—+—__+_++_++__+-_
`ARG
`53 LEU
`55
`0.64
`LYS
`65 LYS
`65
`0.73
`|
`|
`PRO
`54 PRO
`56
`0.79
`a et ee SER
`66 SER
`66
`0.93 — a ae I
`SER
`55 SER
`57
`1.05
`GLY
`67 GLY
`67
`0.78
`|
`F
`GLY
`56 GLY
`58
`0.69
`THR
`68 SER
`68
`0.59
`
`VAL oh oe es Oe oh SamahSadSe Sank57 VAL 59 0.50 : See
`
`
`
`
`PRO
`S8 SER
`60
`0.33
`ALA
`7O ALA
`70
`0.29 |
`|
`THR
`59 ASP
`61
`0.29
`~ — aero SER
`71 THR
`71
`0.35 ete nena cia
`ARG
`60 ARG
`62
`0.40
`LU 7220 72
`0.37
`en eea ees eelellillian i
`|
`.
`=
`—- —-
`is annipe at ——naareeeein rt re re _ olsen icicle en Lee+. far
`
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`
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`Hh smh
`lineal + = 4
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`i A pee ae Ti ta ba tliatiieres pn fener Famed 4 cr
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`|
`i
`_ —— oS —-}- pe fp tt ih eee
`Page 16
`Page16 |
`|
`To Page No.
`
`
`
`Witnessed & Understood by me,
`
`Date
`
`Date
`
`Recorded by
`
`
`
`lfb4.test
`From PDB files:
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`112
`110
`1fb4
`2hfl
`Res
`Res Dist
`LEU
`LEU
`0,
`Q.
`THR
`THR
`oO,
`GLN
`GLN
`ae
`PRO
`SER
`a.
`PRO
`PRO
`0,
`PRO
`i.
`SER
`ALA 1
`2.
`Li
`SER
`1;
`GLY
`Oo.
`THR
`0.
`PRO
`QO.
`GLY
`0.
`GLN
`Oo,
`oO.
`0.
`QO.
`0.
`QO.
`0.
`QO.
`
`Recorded by
`
`Project No.
`Book No.
`
`
`
`
`
`:ai
`
`.
`1.
`0.
`QO.
`0.
`Oo.
`9.
`oO.
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`als
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`0.
`Q.
`Qo.
`|
`
`TITLE
`
`From Page Mo.
`
`ILE
`
`2hfl.test
`2.50
`
`SER
`LEU
`ALA
`ILE
`SER
`GLY
`LEU
`GLU
`ALA
`GLU
`ASP
`GLU
`SER
`ASP
`TYR
`TYR
`cys
`ALA
`SER
`TRP
`TRP
`ASN
`SER
`TYR
`VAL
`GLY
`THR
`GLY
`THR
`Lys
`VAL
`
`VAL
`LEU
`
`4
`
`jFPOoOrPrPSOOOODCOCOCONNNOCOOCOOOOCOCCOCOCOCCCSCoO
`
`Witnessed & Understood by me,
`
`Page 17
`
`iia Mecca
`
`To Page No.___.
`
`
`
`Project No.
`Book No.___
`
`Ce
`
`eee
`
`
`6 F
`
`rom Page No.~%
`
`From PDS files:
`1lfbj.test
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`111
`118
`ifbj
`2mcpRes
`Dist
`Res
`GLU
`ASP
`1.87
`(
`ILE
`ILE
`VAL
`VAL
`MET
`i
`THR
`- Ti
`GLN
`GLN
`SER
`R°o
`PRO
`SER
`SER
`LEU
`SER
`VAL
`SER
`ALA
`GLY
`GLU
`ARG
`VAL
`THR
`MET
`SER
`CYa
`LYS
`SER
`SER
`GLN
`SER
`LEU
`PHE
`LEU
`ALA
`TRP
`TYR
`GLN
`GLN
`LYS
`PRO
`GLY
`GLN
`PRO
`PRO
`LYS
`LEU
`LEU
`ILE
`TYR
`GLY
`ALA
`SER
`THR
`ARG
`GLU
`SER
`GLY
`VAL
`PRO
`ASP
`ARG
`PHE
`THR
`
`iP
`
`gEEHEE
`SaRUSERE
`
`PQUCRRSEESESESSERERERESSERESEREES
`
`Baas
`
`2mcp.test
`2.50
`
`2hfl. test
`2.50
`
`WOAAMNSWHE
`
`GLY
`SER
`GLY
`
`63 GLY
`64 SER
`65 GLY
`
`67 GLY
`GLY
`68 THR
`THR
`.69 ASP
`SER
`70 PHE
`TYR
`71 THR
`SER
`73 THR
`THR
`ILE 74 ILE
`
`Wicca
`
`
`
`UPPHORCOOPRHEHEHUHHOODCOCORPOFPHHEOFOSODOOODOO0CS
`
`.
`
`+—
`
`.
`
`ok
`
`+—+—
`
`+
`
`~
`
`=
`
`r—
`
`+
`
`7
`
`-—
`
`|
`
`From PDB files: 1fbj.test
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`112
`110
`lfbj
` 2hfl
`Res
`Res Dist
`0.64
`63
`63 GLY
`GLY
`= - ae
`: ap
`0.26
`64
`64 SER
`SER
`“™L
`svn oso:
`«(UD as
`0.27
`65
`65 GLY
`GLY
`a ttm 4 os
`0.36
`66
`66 SER
`SER
`THR
`oS THR
`S
`0.81
`0.69
`67
`67 GLY
`GLY
`GIN
`6GLN
`6
`0.20
`0.34
`68
`68 THR
`THR
`SER
`7SER
`7
`0.93
`0.40
`69
`69 SER
`SER
`PRO
`8 PRO
`8
`0.48
`0.07
`70
`70 TYR
`TYR
`MLA
`9 ALA
`9
`0.19
`0.43
`71
`71 SER
`SER
`ILE 10 ILE 10
`0.88
`0.37
`72 LEU 72
`LEU
`THR
`11 MET
`11
`0.41
`0.05
`73 THR
`73
`THR
`ALA
`12 SER
`12
`0.48
`Te WE 4 «b.2¢
`ALA
`13 ALA
`13
`0.65
`SER
`14 SER
`14
`0.74 ae
`LEU
`18 PRO
`15
`1.17
`THR
`76 SER
`76
`0.19
`GLY
`16 GLY
`16
`0.52
`=~ ae 7 fe
`GLN
`17 GLU
`17
`0193
`GLU
`78 GLU
`78
`0.26
`LYS
`18 LYS
`18
`0.55 oe ae re oe
`[. 19 WAL
`is ow
`GLU
`80 GLU
`BO
`0.47
`THR
`20 THR
`20
`0.25 oo oS
`TLE
`21 MET
`21
`0.48
`ALA
`82 ALA
`82
`0.78
`THR
`22 THR
`22
`0.55 ee oe: ee
`CYS
`23 CYS
`23
`0.12
`ILE
`84 GLU
`84
`0.33
`SER
`24 SER
`24
`0.88
`TYR
`85 TYR
`85
`0.15
`ALA
`25 ALA
`25
`0.40
`TYR
`86 TYR
`86
`0.52
`SER
`26 SER
`26
`0.72
`Cre
`87 cya
`87
`8.43
`SER
`27 SER
`27
`0.85
`GLN
`88 GLN
`88
`0.28
`SER
`28 SER
`28
`2.20
`GLN
`89 GLN
`89
`0.19
`VAL
`29 VAL
`29
`1.20
`TRP
`90 TRP
`90
`1.00
`@@ 32 Tre
`31
`2.08
`THR
`91 GLY
`91
`1.97
`LEU
`32 MET
`32
`0.74
`TYR
`92 ARG
`92
`2.33
`HIS
`33 TYR
`33
`0.26
`PRO
`53 ARG
`92
`1.84
`TRP
`34 TRP
`34
`0.19
`LeU 94 ASN
`93
`1.23
`TYR
`35 TYR
`35
`0.30
`TLE
`95 PRO
`94
`0.45
`GIN 36 GEN
`36
`0.08
`THR
`96 THR
`95
`0.26
`GLN
`37 GLN
`37
`0.49
`PHE
`97 PHE
`96
`0.33
`LYS
`38 LYS
`38
`0.49 ,.
`GLY
`98 GLY
`97
`0.62
`SER
`39 SER
`39
`1.20
`ALA
`99 GLY
`98
`0.72
`GLY
`40 GLY
`40
`0.97
`GLY 100 GLY
`99
`0.16
`THR
`41 THR
`41
`0.59
`THR 101 THR 100 0.38
`SER
`42 SER
`42
`0.37
`LYS 102 LYS 101
`0.43
`MRO
`43 PRO 43
`b.gg
`LED 103 Le 102
`0.39
`LYS
`44 LYS
`44
`0.34
`GLU 104 GLU 103
`0.46
`PRO 45 ARG
`45
`0.50
`LEU 105 ILE 104
`0.97
`TRP
`46 TRP
`46
`0.54
`LYS 106 LYS 105
`0.66
`Ike
`47 TLE
`47
`0.38
`ARG 107 ARG106 1.59
`YR 49 TYR
`46
`6.08
`~
`mesg
`GLU
`49 ASP
`49
`1.48
`TLE
`50 THR
`50
`1.38
`SER
`51 SER
`51
`0.55
`LES
`52 LYS
`52 ©. 80
`MO 53 LeU S32
`0.7%
`ALA
`54 ALA
`54
`0.78
`BER
`55 SER
`55 0.0
`@eyY
`56 GLY
`56
`1.25
`VAL
`57 VAL
`57
`6.48
`PRO
`58 PRO
`58
`0.19
`ALA
`59 VAL
`59
`0.74
`ARG
`60 ARG
`60
`0.51
`PHE
`61 PHE
`61
`0.14
`Mm 62 6mR
`62
`0.97
`
`—7—-
`
`—
`
`~*~
`
`—}.
`
`—+
`
`a
`
`os
`
`|
`
`wah
`
`Witnessed & Understood by me,
`
`Date
`
`Page 18
`Page 18
`Invented by
`
`Recorded by
`
`To Page No.
`
`Date
`
`
`
`TITLE
`
`From Page No.
`
`
`
`Project No.
`Book No.
`
`7
`
`
`
`
`
`heDOSCOFPEHFFrOrFOOODOCOOOOFPORPNNENEOOOODCOOCGCOOCOOe
`
`From PDB files: lfbj.test
`teff for CA-CA was
`eecreeen es Sid
`ane
`1fbj
`lrei
`Res
`Res Dist
`ASP
`29
`ILE
`44
`GLN
`64
`MET
`-68
`THR
`-48
`GLN
`«lS
`O.
`QO.
`QO.
`0.
`1.
`ds
`ae
`a.
`Q.
`Q.
`QO.
`Qo,
`Qo.
`QO.
`0.
`oO,
`QO.
`QO.
`a,
`oO.
`aa
`0.
`gq.
`QO.
`Oe
`@.
`Ox
`Qo.
`O.,
`
`me
`ioe
`cuPRO
`Recorded by
`
`SOCCEREENEEEHOSOOPHOSCORDDOODOOOONHOOODCOCOOCOGCHHEHHOOOOOOOCOCOON
`
`irei.
`2.50
`
`lirei.testa
`2.50
`
`PRPROOCORPFERrPHEFRPONFOOCOOCOCOOCOFORPFNRFOOCOOOCOOCOCOCOCOOCOCSS
`
`103
`104
`105
`106
`THR 107 0,97
`i
`
`From PDB files: 1fbj.test
`Maximum distance cutoff for CA-CA was
`NUMRES molecules 162
`111
`107
`1lfbj
`lrei
`Res
`Res
`GLU
`ASP
`ILE
`ILE
`VAL
`GLN
`MET
`THRGLN
`
`woOrwtnwnrwwe
`
`WOndaurWN
`
`SERSER
`
`LEU
`SER
`SER
`VAL
`eer
`ASP
`=
`TLE
`THR
`crsGLN
`ALA
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`Witnessed & Understood by me,
`
`Page 19
`
`To Page No.___.
`
`
`
`8
`
`From Page No.__
`
` Project No.___— Cody
`
`
`BookNo..___———SsTITLE ferdueyFh Cuerage
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`
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`SPSS RASA SSS TAAL AAT TASTES TATA eee eT
`FPB4L, 3FAB and RHE are lambda-type REI, MCPL, FBJL AND 2HFL are kappa-type
`Re KH RR KK RR TRIO TK RITTER KHIR RAT KK IR REE REE KAKA
`a) residues between parentheses are included in beta-sheet based on backbone
`dihedral angles and hydrogen-bonding patterns
`b) letter repeats above sequences correspond to beta-sheet strands
`c) Ll, L2, L3 correspond to hypervariable loops
`da) @ first residue is PCA = pyroglutamyl
`@) small letter in sequence = Ca-Ca distance between proteins > 1.0 A
`SESES TTT A
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`
`Is
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`
`Page 20
`
`To Page No.
`
`
`
`59
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`Witnessed & Understood by me,
`
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`
`a)
`
`‘
`
`Project No.__
`
`From Page No.__
`
`SSFP SSAA SAA SSS SST SSeS T ATA THATSToe
`FB4L,
`3FAB and RHE are lambda-type
`eRe ee RR TeI TI ROK RIK RIT KTR KR RAR RR IK RR RIK RRR REE TE
`a) residues between parentheses are included in beta-sheet based on backbone
`Gihedral angles and hydrogen-bonding patterns
`b) letter repeats above sequences correspond to beta-sheet strands
`¢) Ll, L2, L3 correspond to hypervariable loops
`@) @ first residue is PCA = pyroglutamyl
`e) small letter in sequence = Ca-Ca distance between proteins > 1.0 A
`RR RK TTR RR KR RRR RRR IRR REE RR EEE RER EERE
`A'A'A'A'A'A'
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`a) residues between parentheses are included in beta-sheet based on backbone
`dihedral angles and hydrogen-bonding patterns
`b) letter repeats above sequences correspond to beta-sheet strands
`¢) Ll, L2, L3 correspond to hypervariable loops
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`
`
`Page 21
`LT) ottTT TCT Paseo)
`
`
`
`10
`
`From Page No._#
`
`Project No.
`Book No. .—s-—s
`
`TITLE
`
`Bond Lengths & Angles for KAPPA variable light
`N-Ca Ca-C
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`C-N-Ca N-Ca-C Ca-C=0 Ca-C-N O=C-N N-Ca-Cb Cb-Ca-
`1.459 1.515 1.208 1.288 1.508
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`Bong Lengths & Angles for LAMBDA variable light
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`Bond Lengths & Angles for KAPPA & LAMBDA variable light
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`1.452 1.510 1.190 1.288 1.510 1.3 FD.7 10.8 117.9
`131.9
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`62
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`60
`
`Witnessed & Understood by me,
`
`Page 22
`
`To Page No.
`
`
`
`*
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`Page 23
`
`TITLE
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`‘a J
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`From Page No.__
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`Project No.______
`Book No...
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`11
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`PORK KKK KR RI KK IT I KK RK RIK RIK KIKI TOT KK KK KKK RR KER EK KK RK EK EK KKK KK ERE KKK ERE RKER
`FB4L,
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`hll = human lambda light
`hkl = human kappa light
`Fe I ORR ROR TOI ROR TOR RIT OR ROOK ROR TOI IR ITOK ROR TTI RR TOR IIR I IK FOR TOK RFK IK KK KK RIK RK KHIR IKK
`a) residues between parentheses are included in beta-sheet based on backbone
`dihedral angles and hydrogen-bonding patterns
`b) letter repeats above sequences correspond to beta-sheet strands
`c) Ll, L2, L3 correspond to hypervariable loops
`d) @ first residue is PCA = pyroglutamyl
`e) small letter in sequence = Ca-Ca distance between proteins > 1.0 A
`SOR ITO RO IIR ICR I I IOI III IOI IIR FOI IIR IA ITOK IIR IK KK KIRK IK ERE KIRKE EERE
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`II
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`Witnessed & Understood by me,
`
`Date
`
`Date
`
`Recorded by
`
`Page 24
`
`12
`
`Project No.
` Book No.
`
`FaGsBauGosTasBonsGeyFayfxg
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`Witnessed & Understood by me,
`
`Date
`
`Page 25
`Invented by
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`14
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`Project No.___
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`Book No.
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`TITLE
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`‘
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`
`Date
`
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`Page 26
`Page 26
`Invented by
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`15
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`OCtatFuate,
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`18
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`Project No.
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`Book No...
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`From Page No.__
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`————s—sésT'ITLE Luclbdin
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`«sequence of HuLys, unpublished, Foote and Winter>
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`<90 matches in an overlap of 108: 83.33 percent similarity
`““gaps in first sequence: 0, gaps in second sequence:
`0
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